Osteoporosis – The Causes

Osteoarthritis (OA), a form of arthritis, is defined as a condition of
as a result of aging causes of wear and tear on a joint, affecting over 25 million people in the United States in alone.
A. Causes
1. Process of wear and repair
Osteoarthritis (OA) is a widespread degenerative disease of skeletal joints and is often associated with senescence in vertebrates. OA commonly results from excessive or abnormal mechanical loading of weight-bearing joints (‘wear-and-tear’), arising from heavy long-term use or specific injuries; yet, in the absence of injury, the aetiology of OA remains obscure(6)
Improper repair process of injure of joints can result of symptoms of Osteoarthritis (OA) in old age, according to TCM.
2. Nutrient deficiency
Poor nutritional conditions experienced by moose (Alces alces) early in life are linked to greater prevalence of OA during senescence as well as reduced life expectancy(7).
3. Cartilage
Cartilage is a flexible connective tissue which cushions the ends of bones in your joints and allows the joints to move smoothly. If the cartilage becomes rough  or wears down due to aging or damage, it can causes pain as a result of  bone in the joint rubbing against another bone.
The above causes of Osteoarthritis (OA) are the result of injure, overuse, Rheumatoid Arthritis, etc.
4. Etc.
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Sources
(7) http://www.ncbi.nlm.nih.gov/pubmed/20618843