Jiang Huang or Mao Jiang Huang or Bao Ding Xiang is also known as Tumeric. The acrid, bitter, aromatic and warm herb has been used in TCM as anti coagulation of platelets, anti inflammatory, anti oxidation, antibiotic, antivirus agent and to treat shoulder pain, mood fluctuations, schizophrenia, fever, dizziness, nose bleeding, blood in urine, bleeding not during menses, jaundice, lower back pain, chest and abdomen pain, etc., as it breaks up the Blood Stasis, moves Qi, benefits menstruation, calms pain, etc., by enhancing the functions of stomach, liver and spleen channels.
Ingredients
1. Tumerone
2. Dihydroturmerone
3. Curcuminoids: curcumin
4. Demethoxycurcumin
5. Bisdemethoxycurcumin
6. Borneol
7. Zingberene
8. Arabic gum
9. Glucose
10 Fructose
11. Curcumol
12. Zingiberen
13. Phellandrene
14. Etc.
Health Benefits
1. Diabetes is an inflammatory disease
In the review of TCM hypoglycaemic effects, for example Radix Astragali, Radix Rehmanniae, Radix Trichosanthis, Panax Ginseng, Fructus Schisandrae, Radix Ophiopogonis, Rhizoma Anemarrhenae, Radix Puerariae, Fructus Lycii, Poria, Rhizoma Coptidis, Rhizoma Dioscoreae, Rhizoma Polygonati, Radix Salviae Miltiorrhizae, Radix Glycyrrhizae, Semen Trigonellae, Momordica charantia, Allium sativum, Opuntia stricta, Aloe vera, Cortex Cinnamomi, Rhizoma Curcumae Longae, and so on, have nearly independent anti-inflammatory action, found that TCM might exert hypoglycaemic effects that are partly mediated by the anti-inflammatory mechanisms. However, small amounts of TCM with potent anti-inflammatory action does not have any hypoglycaemic effect. This indirectly indicates that diabetes may be a low-grade inflammatory disease and potent regulation of inflammatory mediators may not be required, according to “Diabetes is an inflammatory disease: evidence from traditional Chinese medicines” by Xie W, Du L.(1)
2. Anti-inflammatory and analgesic effects
In the evaluation of the anti-inflammatory and anti-nociceptive effects and the molecular mechanisms of JCICM-6, a purified extract derived from an anti-arthritic Chinese herbal formula composed of Caulis Sinomenii, Aconiti laterralis Preparata, Rhizoma Curcumae longae, Radix Paeoniae albae, and Cortex Moutan, showed that the positive reference drug, indomethacin at a dosage of 10mg/kg, demonstrated inhibitory potency in both rat models, but it could not augment the production of IL-4, indicating JCICM-6 and indomethacin might possess different pharmacological properties and molecular mechanisms although both have anti-inflammatory and analgesic effects in rats.
These results suggest that JCICM-6 would be a valuable candidate for further investigation as a new anti-arthritic drug, according to “Anti-inflammatory and analgesic effects and molecular mechanisms of JCICM-6, a purified extract derived from an anti-arthritic Chinese herbal formula” by Wong YF, Zhou H, Wang JR, Xie Y, Xu HX, Liu L.(2)
3. Suppressive effects
In the examination of JCICM-6, the extract of an anti-arthritic herbal formula composed of medicinal herbs of Sinomenium acutum, Aconitum carmichaeli DEBX., Curcuma Longa L., Paeonia lactiflora PALL., and Paeonia suffruticosa ANDR., for its mechanism in reducing experimentally-induced inflammation and nociception using nine animal models, found that CICM-6 orally administered in a range of dosages from 0.438 g to 1.75 g/kg significantly and dose-dependently suppressed the paw edema of rats induced by carrageenan or various pro-inflammatory mediators and the ear edema of mice induced by arachidonic acid or TPA, according to “Suppressive effects of JCICM-6, the extract of an anti-arthritic herbal formula, on the experimental inflammatory and nociceptive models in rodents“by Zhou H, Wong YF, Cai X, Liu ZQ, Jiang ZH, Bian ZX, Xu HX, Liu L.(3)
4. Dyspepsia
In the examination of the Curcuma domestica Val. is a medicinal plant, claimed to be effective for dyspepsia, found that 87 per cent of patients receiving Curcuma domestica Val. responded to the treatment. The differences in efficacy between placebo and active drugs were statistically significant and clinically important. Mild and self-limited side effects were observed at similar frequency in the three groups. About 50 per cent of the patients in each group were satisfied with the treatment they received, according to “Randomized double blind study of Curcuma domestica Val. for dyspepsia’ by Thamlikitkul V, Bunyapraphatsara N, Dechatiwongse T, Theerapong S, Chantrakul C, Thanaveerasuwan T, Nimitnon S, Boonroj P, Punkrut W, Gingsungneon V, et al.(4)
5. Etc.
Side Effects
1. Prolonged period of use may increase the risk of stomach ulcer
2. Do not Jiang Huang in case of blood deficiency without qi deficiency and blood stagnation or stasis
3. Do not use the herb in newborn, children or if you are pregnant or breast feeding without consulting first with the related field specialist
4. Etc.
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Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/21205111
(2) http://www.ncbi.nlm.nih.gov/pubmed/18424100
(3) http://www.ncbi.nlm.nih.gov/pubmed/16462027
(4) http://www.ncbi.nlm.nih.gov/pubmed/2699615
Talatisamine is extracted from roots of Aconitum carmichaeli Debx. It inhibited the enhanced I(K) caused by Aβ40 oligomers, attenuated cytotoxicity of Aβ oligomers by restoring cell viability and suppressing K(+) loss related apoptotic response. talatisamine
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