Xian He Cao is also known as Hairyvein
Agrimonia Herb. The acrid, bitter and neutral herb has been used in TCM
to stop bleeding, inhibits Gram-Positive Bacteria, rids of tape worm,
etc., as it promotes hemostasis, stops bleeding, treats dysentery,
eliminates parasites, etc. by enhancing the functions of spleen, lung
and liver channels.
Ingredients
1. Agrimophol
2. Agrimonolide
3. Luteoloside
4. Agrimonin A,B,C
5. Agrimol A～E
6. Tannin acid
7. Sterol
8. Saponin
9. Etc.
Health Benefits
1. Anti anti inflammatory effects
In the study of the effects of Agrimoniae Herba on lipopolysaccharide-induced nitric oxide and proinflammatory cytokine production in BV2 microglial cells by nitric oxide assay, enzyme-linked immunosorbent assay and western blotting, showed that agrimoniae Herba had no cytotoxicity and suppressed lipopolysaccharide-induced nitric oxide production in BV2 microglial cells. Agrimoniae Herba also suppressed lipopolysaccharide-induced production of proinflammatory cytokines such as tumor necrosis factor, interleukin 1 beta and interleukin 6 in a dose-dependent manner. Agrimoniae Herba inhibited the expression of inducible nitric oxide synthase(1).
2. Anti-mite activities
In the study to explore traditional Chinese medicines (TCMs) with anti-mite activities for Dernodex folliculorum in vitro, researchers at the Anhui University of Science and Technology, Huainan, found that Cortex Phellodendri, Herba Taraxac and Herba Agrimoniae et al. had remarkable anti-mite activities to Demodex folliculorum(2).
3. Antinociception
Agrimonia pilosa Ledeb extract shows an antinociceptive property in various pain models. Furthermore, this antinociceptive effect of Agrimonia pilosa Ledeb extract may be mediated by α(2)-adrenergic receptor, but not opioidergic and serotonergic receptors, according to the Hallym University(3).
4. Anti-inflammatory and anti-allergic effects
In the study of the anti-inflammatory and anti-allergic effects of Agrimonia pilosa Ledeb (AP) extract in in vitro cell lines and in vivo mouse model of inflammation and the molecular mechanisms, researchers at the Konkuk University, showed that AP attenuated the activation of macrophages, basophils, and inhibited the OVA-induced airway inflammation. The molecular mechanisms leading to AP’s potent anti-inflammatory and anti-allergic effects might be through regulation of TRIF-dependent and Syk-PLCγ/AKT signaling pathways, suggesting that AP may provide a valuable therapeutic strategy in treating various inflammatory diseases including asthma(4).
5. Antioxidant activities
In the study of Antioxidant activities of aqueous extract from Agrimonia pilosa Ledeb and its fractions indicated that AE shows a moderate antioxidant activity to scavenge DPPH*, O2(-)* and *OH and inhibit beta-carotene bleaching with IC(50) values of 13.0, 33.2, 351, and 11.9 microg/ml, respectively, while its AcOEt-soluble fraction (ESF) and BuOH soluble fraction (BSF) exhibit remarkable efficiencies. The ESF’s IC(50) values of scavenging DPPH*, O2(-)*, and *OH, and inhibiting beta-carotene bleaching are 5.6, 5.8, 171, and 7.6 mircog/ml, respectively(5).
6. Etc.
Side Effects
1. Xian He Cao may cause allergic effect, including nausea and vomiting
2. Etc.
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/20034446
(2) http://www.ncbi.nlm.nih.gov/pubmed/17326398
(3) http://www.ncbi.nlm.nih.gov/pubmed/22563257
(4) http://www.ncbi.nlm.nih.gov/pubmed/22289347
(5) http://www.ncbi.nlm.nih.gov/pubmed/19842137
Ingredients
1. Agrimophol
2. Agrimonolide
3. Luteoloside
4. Agrimonin A,B,C
5. Agrimol A～E
6. Tannin acid
7. Sterol
8. Saponin
9. Etc.
Health Benefits
1. Anti anti inflammatory effects
In the study of the effects of Agrimoniae Herba on lipopolysaccharide-induced nitric oxide and proinflammatory cytokine production in BV2 microglial cells by nitric oxide assay, enzyme-linked immunosorbent assay and western blotting, showed that agrimoniae Herba had no cytotoxicity and suppressed lipopolysaccharide-induced nitric oxide production in BV2 microglial cells. Agrimoniae Herba also suppressed lipopolysaccharide-induced production of proinflammatory cytokines such as tumor necrosis factor, interleukin 1 beta and interleukin 6 in a dose-dependent manner. Agrimoniae Herba inhibited the expression of inducible nitric oxide synthase(1).
2. Anti-mite activities
In the study to explore traditional Chinese medicines (TCMs) with anti-mite activities for Dernodex folliculorum in vitro, researchers at the Anhui University of Science and Technology, Huainan, found that Cortex Phellodendri, Herba Taraxac and Herba Agrimoniae et al. had remarkable anti-mite activities to Demodex folliculorum(2).
3. Antinociception
Agrimonia pilosa Ledeb extract shows an antinociceptive property in various pain models. Furthermore, this antinociceptive effect of Agrimonia pilosa Ledeb extract may be mediated by α(2)-adrenergic receptor, but not opioidergic and serotonergic receptors, according to the Hallym University(3).
4. Anti-inflammatory and anti-allergic effects
In the study of the anti-inflammatory and anti-allergic effects of Agrimonia pilosa Ledeb (AP) extract in in vitro cell lines and in vivo mouse model of inflammation and the molecular mechanisms, researchers at the Konkuk University, showed that AP attenuated the activation of macrophages, basophils, and inhibited the OVA-induced airway inflammation. The molecular mechanisms leading to AP’s potent anti-inflammatory and anti-allergic effects might be through regulation of TRIF-dependent and Syk-PLCγ/AKT signaling pathways, suggesting that AP may provide a valuable therapeutic strategy in treating various inflammatory diseases including asthma(4).
5. Antioxidant activities
In the study of Antioxidant activities of aqueous extract from Agrimonia pilosa Ledeb and its fractions indicated that AE shows a moderate antioxidant activity to scavenge DPPH*, O2(-)* and *OH and inhibit beta-carotene bleaching with IC(50) values of 13.0, 33.2, 351, and 11.9 microg/ml, respectively, while its AcOEt-soluble fraction (ESF) and BuOH soluble fraction (BSF) exhibit remarkable efficiencies. The ESF’s IC(50) values of scavenging DPPH*, O2(-)*, and *OH, and inhibiting beta-carotene bleaching are 5.6, 5.8, 171, and 7.6 mircog/ml, respectively(5).
6. Etc.
Side Effects
1. Xian He Cao may cause allergic effect, including nausea and vomiting
2. Etc.
Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Back to Popular Chinese Herbs http://kylejnorton.blogspot.ca/p/chinese-herbs.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Back to Popular Chinese Herbs http://kylejnorton.blogspot.ca/p/chinese-herbs.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/20034446
(2) http://www.ncbi.nlm.nih.gov/pubmed/17326398
(3) http://www.ncbi.nlm.nih.gov/pubmed/22563257
(4) http://www.ncbi.nlm.nih.gov/pubmed/22289347
(5) http://www.ncbi.nlm.nih.gov/pubmed/19842137
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