Dementia is a neuropsychiatric disorder as a result of cognitive impairment and behavioral disturbances. The behavioral and psychological symptoms of dementia (BPSD) are common, contributing to caregiver burden and premature institutionalization.
About 5-8% of all people over the age of 65 have some forms of dementia, and this number doubles every five years above that age.
Alzheimer's disease worsens over time and it is fatal.
American typical diet contains a high amount of saturated and trans fat, artificial ingredients with fewer fruits and vegetable which can lead to dementia and other kinds of diseases.
As the disease progression, the brain tissue of the patient with AD has fewer and fewer nerve cells and connections.
In the elderly, age-related to the changes in the brain include atrophy (shrinking) of certain parts of the brain, inflammation associated with overexpression of free radicals in the induction of neuro cytotoxicity that affects the energy production within cells and long-term accumulated of plaques in the neurons caused by unhealthy diet are many prevalent risk factors that elevate the early onset and progression of the disease.
According to the experimental results, researchers suggested that CBE showed a strong anti-AD activity by inhibiting the level of Aβ toxicity and promoting memory health, the two major pathological parameters in AD.
Based on the findings, researchers said, "CBE prominently showed the preventive efficacy, providing a basis for further investigation of these effects in mammals".
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Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
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Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
(1) Cranberry extract supplementation exerts preventive effects through alleviating Aβ toxicity in Caenorhabditis elegans model of Alzheimer's disease by Guo H1, Dong YQ2, Ye BP. (PubMed)