Tuesday, 6 November 2018

Herbal Chickweed, The Natural and Potential Remedy Which Protects Our Liver Against Hepatitis

By Kyle J. Norton, Master of Nutrition

Scientists may have found a single whole herb which processes a significant effect in reducing risk and treatment of hepatitis with no side effects, some studies suggested.

Hepatitis is a group of infectious disease characterized by the inflammation of the liver.

Most cases of hepatitis are caused by viral infection, such as hepatitis A, B, and C. However, the disease also can be induced by excessive alcohol drinking and long-term intake of certain medication such as the popular Nonsteroidal anti-inflammatory drugs (NSAIDs).

Genetic preposition such as gene and certain medical conditions such as Cryoglobulinemia, a disease with an abnormality of the antibody and B-cell non-Hodgkin's lymphoma are also found to elevate the risk of the disease onset.

Dr. Zheng Zeng in the study "Human genes involved in hepatitis B virus infection", wrote, " There is an approximate 90% risk of becoming a persistent carrier following perinatal infection in infants born to e antigen positive carrier mothers and a 30% risk in pre-school children. Only 5%-10% of adults become persistent carriers following infection".

Hepatitis is a very contagious disease. people who eat food or drink beverages contaminated with the feces of an infected person are easily infected by the virus. 

Fishes and selfish that grow in the polluted water are also found to infected people with hepatitis virus.

Other risk factors associated with liver inflammation also include liver disease, cirrhosis, and liver toxicity.

According to the investigation of hepatitis infection among 563 adult Swedish expatriates suggested, "The most frequently reported recognised risk factors for the acquisition of viral hepatitis (as reported in a self-administered questionnaire) were having received an inoculation during medical or dental treatment, reported by 45% of all subjects, and having had sexual contact with the indigenous population, reported by 35%" and "the prevalences of hepatitis A virus (HAV) and hepatitis C virus (HCV) markers in these expatriates were of the same magnitude as previously reported in the general Swedish population, 8% and 0.3%, respectively, the prevalence of markers for a past or present HBV infection was about twice as high (5%)".

Chickweed is a cool-season annual plant often eaten by chickens., genus S. media, belonging to the family Caryophyllaceae, native to Europe.

The herb has been used in herbal medicine to treat skin conditions, indigestion, eczema, cough, rashes, etc. and as astringent, carminative, demulcent, diuretic, expectorant, laxative, refrigerant, vulnerary agent.

In the study to reaffirm the use of Chickweed in traditional Chinese medicine for treatment of viral infection, researchers at the Jiangsu Provincial Academy of Chinese Medicine conducted an evaluation to examine anti-hepatitis virus of a fresh juice made from the herbal medicine.

All the fresh chickweed juices were prepared by the macroporous resin and ultrafiltration technology.

In vitro, the human HBV-transfected liver cell line HepG2.2.15. after treatment with fresh chickweed juices for 6 or 9 days, with the injection of 30 μg/mL SM-3 effectively suppressed the secretion of HBsAg and HBeAg with inhibition rates of 27.92% and 25.35% after 6 days of treatment of HepG2.2.15 cells, respectively.

Application of SM-3 reduced the level of HBV DNA in a dose-dependent manner.

Furthermore, the SM-3 also exerted a potential effect in the reduction in HBV antigens.

Moreover, in the examine the characterization and quantitation of the chemical composition of SM-3, researchers discovered that the efficacy of SM-3 in the inhibition of the human HBV-transfected liver cell line HepG2.2.15 was results of antiviral activities of the presence of flavonoid C-glycosides, polysaccharides, and protein found in the herb.

These results strongly suggested that herbal Chickweed possesses potential anti-HBV activity in vitro.

Additionally, in the examine the anti-hepatoma activity on five human liver-cancer cell lines, i.e. HepG2/C3A, SK-HEP-1, HA22T/VGH, Hep3B and PLC/PRF/5. of 15 15 herbal medicines used as folk medicine in Canada were evaluated by the McGill University.

Chickweed was found to exert a significant effect in the protection of the liver against the growth of all five cell lines, HepG2/C3A, SK-HEP-1, HA22T/VGH, Hep3B and PLC/PRF/5.

Taken altogether, Chickweed may be considered a function herbal medicine for the prevention and treatment of hepatitis.

However, due to the limitation of the above studies, additional data collection large example size and multi-centers studies performed with human consumption of the whole food or its bioactive compounds during the course of the disease will be necessary to complete the picture of Chickweed anti-hepatitis possibilities.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

(1) In vitro anti-hepatoma activity of fifteen natural medicines from Canada by Lin LT1, Liu LT, Chiang LC, Lin CC. (PubMed)(2) Bioactive constituents from Chinese natural medicines. XIV. New glycosides of beta-carboline-type alkaloid, neolignan, and phenylpropanoid from Stellaria dichotoma L. var. lanceolata and their antiallergic activities by Morikawa T1, Sun B, Matsuda H, Wu LJ, Harima S, Yoshikawa M.(PubMed
(3) Anti-hepatitis B virus activity of chickweed [Stellaria media (L.) Vill.] extracts in HepG2.2.15 cells by Ma L1, Song J, Shi Y, Wang C, Chen B, Xie D, Jia X.(PubMed)
(4) Evaluation of hepatoprotective activity of water-soluble polysaccharide fraction of Stellaria media L. by Gorina YV1, Saprykina EV, Gereng EA, Perevozchikova TV, Krasnov EA, Ivanova EV, Fait EA, Baranova OV. (PubMed)
(5) In vitro anti-hepatoma activity of fifteen natural medicines from Canada by Lin LT1, Liu LT, Chiang LC, Lin CC. (PubMed)

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