Strawberries may process strong neuroprotective effects by protecting the brain cell integrity and viability against the onset of neurological diseases, some scientists suggested.
A neuroprotective effect is an event that protects the central nervous system (CNS) by relatively preserving of neuronal structure and/or function.
Neurological diseases are the medical conditions of brain disorder. Anything that involves the structural, biochemical or electrical abnormalities in the brain, spinal cord or other nerves, including brain damage are considered as neuro diseases.
Most common neurodegenerative diseases in the elderly are dementia. Depending on the brain regions that are damaged or dysfunction, dementia can be Parkinson's, Alzheimer's, and Huntington's disease.
Strawberries are a genius of Fragaria × ananassa belongs to the family Roseaceae.
The fruits have been grown all over the world in a suitable climate for commercial profits and health benefits.
The major chemical compounds include anthocyanin and ellagitannins and p-Hydroxybenzoic acid, p-coumaric acid, ellagic acid, cyanidin-3-glucoside, pelargonidin-3-glucoside, kaempferol, quercetin, and myricetin.
In the assessment of the neuroprotective effects of a unique class of nutraceutical antioxidants, anthocyanins, against the MOS-induced death of cultured cerebellar granule neurons (CGNs), researchers at the University of Denver conducted a study to evaluate the effect of callistephin and kuromanin, the anthocyanins derived from strawberries.
Additionally, in the reassessment the mechanisms involved in the repair or elimination of damaged neurons, Dr. Winter AN, the team leader scientist at joint study led by the University of Denver, launched an evaluate to compare the ability of same derivatives of anthocyanins, callistephin (pelargonidin-3-O-glucoside) and kuromanin (cyanidin-3-O-glucoside) in the protection of cerebellar granule neurons from damage induced by either oxidative or nitrosative stress.
These results suggested that anthocyanins may be used for treating neurodegenerative diseases, even kuromanin and compounds that share similar chemical characteristics may be more effective than the therapeutic agents forthan callistephin and related (non-catechol) compounds.
Taken all together, intake of strawberry daily and regularly may have a profound effect in the protection the brain neurons against the onset of neurological diseases.
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Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
(1) The strawberry: composition, nutritional quality, and impact on human health. by Giampieri F, Tulipani S, Alvarez-Suarez JM, Quiles JL, Mezzetti B, Battino M.(PubMed)
(2) Phenolic Composition of Strawberry Genotypes at Different Maturation Stages(ACS Publication)
(3) The Promise of Neuroprotective Agents in Parkinson’s Disease by Stacey E. Seidl and Judith A. Potashkin(Frontiers in Neurology)
(4) Neuroprotective effects of anthocyanins on apoptosis induced by mitochondrial oxidative stress. by Kelsey N, Hulick W, Winter A, Ross E, Linseman D.(PubMed)
(5) Chemical basis for the disparate neuroprotective effects of the anthocyanins, callistephin, and kuromanin, against nitrosative stress by Winter AN1, Ross EK1, Khatter S1, Miller K2, Linseman DA. (PubMed)
(6) Berry fruit supplementation and the aging brain. by Shukitt-Hale B, Lau FC, Joseph JA.(PubMed)
(7) Nutrition and Lifestyle Intervention on Mood and Neurological Disorders by Null G1, Pennesi L2, Feldman M. (PubMed)