Wednesday, 8 August 2018

* Male + Smoking + High Caffeinated Coffee Consumption = ↑ Risk of Lung Cancer, Scientists Found


Kyle J. Norton, Master of Nutrition

Recent study suggested that regular high amounts of caffeinated coffee consumption may be associated to increase risk of lung cancer.

Lung cancer is a medical condition characterized by abnormal growth of the cells in the lung's tissue.

At the advance stage, the cancerous cells can travel a distance away from the lung to infect other healthy tissue and organs

Most common form of primary lung cancers are derived from epithelial cells. 

In US, lung cancer is the leading cause of cancer death. Approximately, 88,329 men and 70,354 women died from the disease, according to 2007 statistic.

Non-small cell lung cancer is the most common type of lung cancer, developed in the squamous-cells of the lung. 

Although the exact causes of lung cancer are debatable, some researchers suggested that smoking, second hand smoke, exposure to certain chemicals, lung disease, family history,..... and excessive alcohol drinking are associated to substantially increased risk of the disease.

Most common symptoms are coughing up blood.and shortness of breath, however, some patients may also experience symptoms of chest pain, lung fluid retention, wheezing and hoarseness,..... and bone pain.

If you suffer from some of the above symptoms, please see your doctor to rule out the disease possibility

Coffee, a popular and social beverage all over the world, particular in the West, is a drink made from roast bean from the Coffea plant, native to tropical Africa and Madagascar.

In the clarified risk of coffee in induced lung cancer, the Shanghai Institute of Pharmaceutical Industry conducted a search in the data base of PubMed and Embase, from 1966 to January 2009. In 5 prospective studies and 8 case-control studies involving 5347 lung cancer cases and 104,911 non-cases selected, researchers found that
* Coffee high amount intake is associated to a significant positive lung cancer risk.

*. Risk of lung cancer is increased by 14% for additional 2 cups consumed daily.

Dr. Wang Y, the lead author said, "a linear dose-response relationship exists between (caffeinated) coffee consumption and risk of lung cancer".

Interestingly, prospective studies conducted in America and Japan showed a significantly associated with increased risk of lung cancer in highest coffee consumption, but borderline significantly associated with decreased risk of lung cancer in non-smokers in compared to studies conducted from other countries.

And people drinking decaffeinate coffee showed a decreased risk of lung cancer in all studies.

Other, in the review of seventeen studies (5 cohort and 12 case-control studies) involving 12 276 cases and 102 516 controls met the predetermined inclusion criterion, extracted from data base of literature, the total risk of caffeinated coffee intake and lung cancer incidence was 1.17 in compared to non drinkers.

 Also in compared to non drinkers, the relative risk of lung cancer was associated to numbers of cup per day consumed,
* 1.10 (95% CI: 0.92-1.31) for ⩽1 cup per day,

* 1.10 (95% CI: 0.93-1.30) for 2-3 cups per day,
 and
* 1.20 (95% CI: 1.02-1.39) for ⩾3 cups per day.


More importantly, Dr. Xie Y, the lead author said, " Significant associations for high coffee intake with increased risk of lung cancer were observed in men (OR=1.41 95% CI: 1.21-1.63), but not in women (OR=1.16, 95% CI: 0.86-1.56), ..... but not in nonsmokers (OR=0.85, 95% CI: 0.64-1.11)".


Taking altogether, there is no doubt that regular coffee intakes of large amounts is associated linearly in increased risk of lung cancer in men and smokers.

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Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Coffee and tea consumption and risk of lung cancer: a dose-response analysis of observational studies by Wang Y, Yu X, Wu Y, Zhang D.(PubMed)
(2) Coffee consumption and risk of lung cancer: a meta-analysis by Tang N1, Wu Y, Ma J, Wang B, Yu R.(PubMed)
(3) Lung cancer by Kyle J. Norton