Tuesday, 20 January 2015

(Preview)Most common diseases of 50 plus - Diseases of Central Nervous system(CNS): Dementia Treatments: Herbal Lavender

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By Kyle J. Norton Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

         Diseases of Central Nervous system


About 5-8% of all people over the age of 65 have some form of dementia, and this number doubles every five years above that age. Dementia is the loss of mental ability, severe enough to interfere with people's every life and Alzheimer's disease is the most common type of dementia in aging people.

V. Treatments
B. In herbal medicine perspective
Lavender is a flower plant of the genus Lavandula, belonging to the family Lamiaceae, native to Asia. The herb has been used in traditional medicine as antimicrobial, anti-inflammatory and mood alleviating(618), and burns and insect bites effects(623), as well as depression, stress and mild anxiety(621)  probably through its phytochemicals(constituents (-)-linalool, (+)-α-pinene and (+)-limonene ) in modulation of the immune and neuroendocrine system by interfering with metabolism of tryptophan(618).
a. Spatial performance
Lavender extract (LE, in AD animal model  showed effectively in improvement of spatial performance, through atentuation of Aβ production in histopathology of hippocampus(619) which involved in memory forming, organizing, and storing. Its aqueous extract of lavender (Lavandula angustifolia), also significantly improved the performance of control and reverse spatial learning amd memory deficits(621) in AD rats(620). Inhaled lavender oil, oxidative stress induced rat, exhibited neuroprotective effects through its potent antioxidant and antiapoptotic activities(622).

b. Behavioural symptoms 
Lavender aromatherapy, according to Kongju National University, is effective on emotions and aggressive behavior of elderly with dementia of the Alzheimer's type(624)and reduced disruptive behaviour in people with dementia(625). In agitated behaviour in severe dementia, 2% lavender oil aromatherapy stream administered on the ward for a two hour period, showed a modest effects in compared with placebo(626). The effectiveness of the herb in reduced behaviours in individuals with dementia potentially provide a safer intervention rather than reliance on pharmacology alone. The study's findings will translate easily to other countries and cultures(627).

c. Cognitive performance and Mood disorders
Aromatherapy applied to  28 elderly people with dementia, 17 of whom had Alzheimer's disease (AD), showed significant improvement in personal orientation related to cognitive function on both the Gottfries, Brane, Steen scale (GBSS-J)and Touch Panel-type Dementia Assessment Scale (TDAS), according to Tottori University(628) and emotions and aggressive behavior of elderly with dementia, according to Kongju National University(629). In emotional parameters,  lavender essential oil also significantly enhance mood responses, including anxiety(631)(633) and depression(632)(634) probably through its relaxing effect(630).

d. Etc.
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(618) http://www.ncbi.nlm.nih.gov/pubmed/25515049
(619) http://www.ncbi.nlm.nih.gov/pubmed/25561935
(620) http://www.ncbi.nlm.nih.gov/pubmed/21441971
(621) http://www.ncbi.nlm.nih.gov/pubmed/22402245
(622) http://www.ncbi.nlm.nih.gov/pubmed/23351960
(623) http://www.ncbi.nlm.nih.gov/pubmed/?term=lavender+burns+and+insect+bites+effects
(624) http://www.ncbi.nlm.nih.gov/pubmed/15860944
(625) http://www.ncbi.nlm.nih.gov/pubmed/23837414
(626) http://www.ncbi.nlm.nih.gov/pubmed/11994882
(627) http://www.ncbi.nlm.nih.gov/pubmed/20649945
(628) http://www.ncbi.nlm.nih.gov/pubmed/20377818
(629) http://www.ncbi.nlm.nih.gov/pubmed/15860944
(630) http://www.ncbi.nlm.nih.gov/pubmed/22612017
(631) http://www.ncbi.nlm.nih.gov/pubmed/19968674
(632) http://www.ncbi.nlm.nih.gov/pubmed/24559818
(633) http://www.ncbi.nlm.nih.gov/pubmed/19258850
(634) http://www.ncbi.nlm.nih.gov/pubmed/16520572

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