Friday, 11 September 2020

Omega-3 Fatty Acids Processes Anti-Inflammatory Effects

By Kyle J. Norton

Inflammation is a process of the immune system that responds to harmful pathogens.

Inflammation can be acute or chronic. In the acute phase of infection, the immune system after receiving information from the neurons, macrophages, the largest white blood cells in the first line of defense stimulate the production of blood palette to cover the wound and the production of inflammatory cytokines to kill off micro-organisms, leading to symptoms of fever, redness, and swelling.

However, in some cases, the overproduction of proinflammatory cytokines may damage nearby healthy cells and tissues, causing the formation of scars.

In severe cases, a protein with duo functions in the production of pro and anti-inflammatory cytokines which produce anti-inflammatory cytokines under normal condition also switch to produce pro-inflammatory cytokines.

Most cases of acute inflammatory are resolved within a few days without causing damage to the wound tissues.

Chronic inflammatory diseases are the class of conditions involved in low-grade inflammation to the affect tissue or organ.

Some researchers suggested that the immune system has evolved over thousands of years to kill off the foreign invasive pathogens within a period of time, normally between 3 to 8 weeks. If the immune fails to do so, it will adapt to the new change, leading to chronic inflammation.

There are several factors that cause the onset of the conditions. Some scientists indicated untreated acute inflammation, such as an infection or injury and an autoimmune disorder involved immune system mistakenly attacking healthy tissue are the most causes of chronic inflammatory diseases.

Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.

The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

On finding a potential phytochemical for the treatment of chronic inflammatory diseases, researchers examined the effect of Omega 3 fatty acids on the development of atherosclerosis and increase the risk of cardiovascular diseases (CVDs).

According to the results of studies, polyunsaturated fatty acids (PUFAs) and its eicosapentaenoic acid and docosahexaenoic acid (omega 3), and arachidonic acid (omega 6) exerted strong anti-inflammatory properties.

Omega-3 fatty acids supplementation showed an inverse association with the risk, inflammation, obesity, and CVDs.

Furthermore, Omega-3 PUFAs also decreased the production of inflammatory mediators and had a positive effect on obesity and diabetes mellitus type-2.

Taken altogether, Omega-3 fatty acids may be considered an anti-inflammatory remedy, pending to the confirmation of the larger sample size and multicenter human study.

Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Anti-inflammatory effects of omega 3 and omega 6 polyunsaturated fatty acids in cardiovascular disease and metabolic syndrome by Tortosa-Caparrós E1, Navas-Carrillo D2, Marín F1, Orenes-Piñero E. (PubMed)

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