Green Bean Protects the Liver Against Hepato-Toxicity

By Kyle J. Norton

The liver is the largest internal organ located in the upper right portion of the abdomen, beneath your diaphragm and above your stomach.

The liver not only plays a critical role to filter the blood coming from the intestine before passing them to other parts of the body but also protects our body against toxin by detoxifying chemicals and metabolizes drugs.

Additionally, the liver also inhibits oxidative stress by producing the antioxidant enzyme that counters the expression of free radicals in the body.

The hepatoprotective effect is the action of the prevention of the liver against liver damage or toxicity.

There is no single cause of liver diseases. Researchers suggested that virus such as hepatitis A, B, C, long-term excessive alcohol drinking and genetic mutation inherited from the parents is the major risk factors associated with the early onset of the diseases.

Some researchers suggested overweight and obesity and congenital diseases such as Hemochromatosis and Wilson’s disease also are the prevalent risk factors of liver damage and diseases.

Liver damage and disease can also be caused by long-term intake of certain medications, such as paracetamol and Illegal drugs such as cocaine.

Hepatotoxicity is a condition caused by the accumulation of toxin in the liver, leading to liver dysfunction or reduced liver function.

Acute liver toxicity is caused by short-term exposure to toxic chemicals such as an overdose of medication.

Chronic liver toxicity is due to long-term exposure to toxic substances including excessive alcohol drinking and long term use of certain medicines.

Green bean is a genus of Phaseolus Sensu Stricto, containing 55 difference species, belongings to the family Fabaceae and native to the New World tropics and grown in Europe for its attractive flowers and fleshy immature pods.

The veggie can be classified into two major groups, bush beans, and pole beans.

On finding potential mixture with liver protective activity, researchers compared the herbal extract mixture and yogurt added to the herbal extract mixture including alder tree, labiate herb, milk thistle green bean-rice bran fermentation, and turnip were tested for their protective and therapeutic effects on ethanol-induced liver injury.

Based on the results of the experiment, the herbal extract mixture, yogurt, and commercial drugs for two weeks treatment prior to administering a single oral dose of ethanol (3 g/kg body weight), the herbal extract mixture plus yogurt added, exerted significant protection against ethanol-induced toxicity comparable to the commercial drug.

More importantly, herbal extract mixture co-treatment with yogurt showed a strong activity to protects the liver against a triple oral dose of ethanol (2 g/kg body weight, over one week) ethanol toxicity.

Based on results the long term treatment, scientists said, "When compared to the positive control, further treatment with both the herbal extract and yogurt significantly reduced liver injury and resulted in a lower grade of lipid deposition".

Taken altogether, green bean in the combination of with other herbal medicine may be considered functional food for the prevention and treatment of liver diseases, pending to the confirmation of the larger sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Protective and therapeutic effects of an extract mixture of alder tree, labiate herb, milk thistle green bean-rice bran fermentation, and turnip against ethanol-induced toxicity in the rat by Baek MW1, Seok SH, Lee HY, Kim DJ, Lee BH, Ahn YT, Lim KS, Huh CS, Park JH. (PubMed)