Sunday, 13 September 2020

Ashwagandha, the Promising Nootropic, Scientists Find

By Kyle J. Norton

Nootropics are medications that process cognitive-enhancing property.
In other words, Nootropics, including supplements, herbal remedies, and others improve cognitive function, such as executive functions, memory, creativity, or motivation.

A neuron or nerve cell made of a cell body (also called soma), dendrites and an axon, is a cell in the nervous system that carries electrical impulses.

Neurons are core components of the brain, spinal cord and peripheral nerves that play an essential role to process and transmit information.

Neuron dysfunction has been found to induce neurodegenerative diseases.

A neuroprotective effect is an event that protects the central nervous system (CNS) by relatively preserving the neuronal structure and/or function.

Neurological diseases are the medical conditions of brain disorder. Anything that involves the structural, biochemical or electrical abnormalities in the brain, spinal cord or other nerves, including brain damage are considered neuro diseases.

The most common neurodegenerative diseases in the elderly are dementia. Depending on the brain regions that are damaged or dysfunction, dementia can be Parkinson's, Alzheimer's, and Huntington's disease.

Genetic mutation inherited from parents such as the NOTCH3 gene is the most common autosomal dominant inherited cause of stroke and vascular dementia. 

On finding a potent compound that processes the neuroprotective effect, researchers examined the effects of withanamides in W.somnifera Nootropics for enhancing and maintaining brain health and function.

Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean.

The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.

According to differentiation, Ashwagandha extracts and active principles not only processed the anticancer, anti-stress and remedial potential for aging but also protected the brain neurons against neurodegenerative pathologies.

Additionally, Ashwagandha leaf extracts showed a multidimensional ranking potential from the differentiation of neuroblastoma and glioma cells.
Moreover, the leaf extracts also reversed the Alzheimer's and Parkinson's pathologies and protected the brain cells' integrity against environmental neurotoxins and enhancement of memory.

Taken altogether, Ashwagandha may be considered a functional herb as nootropics including Parkinson's disease, Alzheimer's disease, pending to the result of larger sample size and multicenter study

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Nootropic potential of Ashwagandha leaves: Beyond traditional root extracts by Wadhwa R1, Konar A1, Kaul SC. (PubMed)

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