Tuesday, 4 August 2020

Herbal Angelica Inhibits Lipid Oxidation in Vivo

By Kyle J. Norton

Lipids are insoluble substances or chemicals,. Lipids are the main constituents of plant and animal cells.

Lipid oxidation is a condition of oxidative lipid generation.

In other words, the molecule in the lipid has an unpaired electron in the outer ring.

Free radicals are unstable atoms that have an unpaired electron in the outer most ring. In order to become stable, they must donate or intercept an electron from other stable atoms, leading to a chain reaction that can not be stopped until all electrons in the outer ring are paired or inhibited by antioxidants.

Overexpression of free radicals caused by depletion of antioxidant enzymes produced by the host body has been found epidemiologically inducing protein and lipid damage and alternation of cell DNA in facilitating the risk of chronic diseases.

Cholesterol and triglycerides are lipids.

Triglyceride is fat in the blood that comes from the outside source used by the body to convert to energy.

Triglyceride is stored in the fat cells used to produced energy between meals and in the case when food is scarce.

Compared to cholesterol, triglycerides at high levels are also associated with the risk of heart disease, particularly in people with high levels of LDL and low levels of HDL.

Evolutionally, fat accumulation is considered a defense mechanism in the human body where excess fat is stored when food is plentiful and release to produce energy when food is scarce.

Cholesterol is a waxy substance that is produced either by the liver or injected from animal food sources.

Cholesterol found in our body is needed for our body to build cell walls, hormones, and vitamin D, and create bile salts that aid digestion. However, too much of them, in most cases due to the intake of animal protein can cause plaques built up on the arterial wall, the major cause of heart disease and stroke.

Diseases associated with lipid oxidation are atherosclerosis, ischemia-reperfusion, heart failure, Alzheimer's disease, rheumatic arthritis, cancer, and other immunological disorders

Angelica or Dang Qui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.

The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.

On findings a potential compound for the treatment of oxidative stress, researchers examined the effect of the extracts of Angelica Sinensis (EAs) on lipid oxidation in fish feeds compared with ethoxyquin (EQ).

The study included fish fed respectively added with EQ, and ethyl ether extract, ethyl acetate extract (EAE), acetone extract, ethanol extract (EE) and aqueous extract (AQE) of Angelica Sinensis, except for the control.

According to the tested analysis, EAs and EQ showed an inhibition of the levels of lipid oxidation in fish feeds.

However, compared to all extracts in EAs, the EAE showed the strongest protective effects against lipid oxidation.

Furthermore, EAE at high concentrations showed a stronger effect on lipid oxidation compared with EQ.

Taken altogether, Herbal Angelica processes anti- lipid-oxidation activity, pending to larger sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Effects of Angelica sinensis extracts on lipid oxidation in fish feeds and growth performance of juvenile Jian carp (Cyprinus carpio var. Jian) by Li H1,2, Yang D2, Li Z2, He M2, Li F2, Jiang J3, Tang S2, Peng P2, Du W2, Ma Y2, Liu Y. (PubMed)

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