Wound healing is the natural process of repair of skin damage and injury.
The process of skin healing in humans is gone through several stages. First, the immune system after sensing the skin wound activates the immune first-line defense stimulating the constriction of the blood vessel to reduce blood flow, activate platelets, and many different clotting factors to cover the wound area.
Then, the white blood cells also up-regulate the proteins associated with the production of proinflammatory cytokines to the site of infection to kill off all the invasive organisms.
In most cases, due to the overproduction of proinflammatory cytokines, patients may experience symptoms of fever, and localized pain, redness, and swelling.
The process of skin healing in humans is gone through several stages. First, the immune system after sensing the skin wound activates the immune first-line defense stimulating the constriction of the blood vessel to reduce blood flow, activate platelets, and many different clotting factors to cover the wound area.
Then, the white blood cells also up-regulate the proteins associated with the production of proinflammatory cytokines to the site of infection to kill off all the invasive organisms.
In most cases, due to the overproduction of proinflammatory cytokines, patients may experience symptoms of fever, and localized pain, redness, and swelling.
* The first phase of wound healing is cover up the wound. In this phase, the immune first line of defense white blood cells stimulates the emergency repair system in the production of blood clotting to block the drainage.
* In phase 2, the white blood cells activates the proteins associated with the inflammatory cytokines to destroy the pathogens before they can enter the body through the wound.
* In phase 3, new blood vessels and tissues are formed in the damage and injury area.
* The recovery phase.
However, the healing process is easier said than done, the complex process in many cases can be interrupted by local and systemic factors, including moisture, infection, age, and nutritional status, leading to the formation of scar
Selected animals in the study were divided into four groups of six each (n = 6) as follow,
* The experimental group 1 and 2 animals were treated topically with the grape and cranberry oil (100 mg/kg body weight), respectively.
* The controls were treated with petroleum jelly.
* The standard group of animals was treated with mupirocin ointment (100 mg/kg body weight).
According to the healing process assays,
* On day 13, animals treated with cranberry oil showed a better reduction in the wound area of 88.1% compared with grape-oil treated of 84.6%, 74.1% in control and 78.4% in standard group animals.
Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.
On finding a potential compound for the promotion of skin healing, researchers compared the pharmacological properties of the phytochemical constituents present in oils of cranberry on wound healing.
On finding a potential compound for the promotion of skin healing, researchers compared the pharmacological properties of the phytochemical constituents present in oils of cranberry on wound healing.
* The experimental group 1 and 2 animals were treated topically with the grape and cranberry oil (100 mg/kg body weight), respectively.
* The controls were treated with petroleum jelly.
* The standard group of animals was treated with mupirocin ointment (100 mg/kg body weight).
* On day 13, animals treated with cranberry oil showed a better reduction in the wound area of 88.1% compared with grape-oil treated of 84.6%, 74.1% in control and 78.4% in standard group animals.
* Furthermore, the hydroxyproline content of the granulation tissue was significantly higher in the animals treated with cranberry and the grape-oil compared to control and standard groups.
In other words, cranberry oil exerted the strongest effects in the promotion of wound healing compared to other experimental groups.
Collectively, researchers wrote, "Comparative investigation of the curative properties of the oils of V. vinifera and V. macrocarpon revealed a significant result which suggests their wound-healing potential".
Sources
(1) Wound-healing properties of the oils of Vitis vinifera and Vaccinium macrocarpon by Shivananda Nayak B1, Dan Ramdath D, Marshall JR, Isitor G, Xue S, Shi J. (PubMed)
Taken altogether, cranberry oil may be considered a topical remedy for speeding up wound healing, pending to the confirmation of the larger sample size and multicenter human study.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
(1) Wound-healing properties of the oils of Vitis vinifera and Vaccinium macrocarpon by Shivananda Nayak B1, Dan Ramdath D, Marshall JR, Isitor G, Xue S, Shi J. (PubMed)
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