Thursday, 21 April 2016

Most Common Disease of 50+: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs)- Gout - Diseases associated with Gout - Psoriasis

Kyle J. Norton (Scholar and Master of Nutrients, all right reserved)Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. According to a community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home, musculoskeletal pain was reported by 57% of those interviewed(*).

Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia


Gout mostly effected one joint is an acute and recurrent condition of arthritis as a result of uric acid building up in blood, inducing joint inflammation.

                   Diseases associated with  Gout

According to the UK Gout Society,  diseases associated to gout may include

12. Psoriasis  
Psoriasis is an autoimmune diseases induced abnormal skin path with expression of redness, itchy, and scaly. According to the joint study led by the University of Trieste, the increased incidence of a large number of diseases which share an inflammatory origin probably due to the pro-inflammatory cytokine spillover from active psoriatic lesions leading to a large inflammation on distant tissues(95).
Methotrexate, a conventional medicine may be an effective therapy for extensive and severe forms of psoriasis if patients are selected carefully and monitored regularly in the dose of <15-20 mg/week(96) Dr. Haustein UF and Dr. Rytter M. insisted(96).
According to the joint study led by the Brigham and Women's Hospital and Harvard Medical School, Boston, individuals with psoriasis have increased blood levels of uric acid. In the documented 2217 incident cases of gout during follow-up. Psoriasis was associated with an increased risk of subsequent gout with a multivariate HR of 1.71(97).
Dr. Lai YC and Dr.Yew YW said, " A raised serum uric acid level may be a consequence of metabolic syndrome, which in turn is associated with psoriasis"(98).

Recent studies by some renowned institutions suggested that green tea(99) and grape(100) may be the next generation of ingredient extracted from natural sources for reduced risk and treatment of psoriasis.
If you need more information of the above smoothie, please visits, The Unbelievable Smoothie Green Tea and Grape for reduced risk and Treatment of Psoriasis(101).

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(95) Increased airway inflammation in patients with psoriasis by Damiani G1, Radaeli A2, Olivini A2, Calvara-Pinton P3, Malerba M2.(PubMed)
(96) Methotrexate in psoriasis: 26 years' experience with low-dose long-term treatment by Haustein UF1, Rytter M.(PubMed)
(97) Psoriasis, psoriatic arthritis and risk of gout in US men and women by Merola JF1, Wu S2, Han J3, Choi HK4, Qureshi AA5.(PubMed)
(98) Psoriasis and uric acid: a population-based cross-sectional study by Lai YC1, Yew YW2.(PubMed)
(99) Green tea protects against psoralen plus ultraviolet A-induced photochemical damage to skin by Zhao JF1, Zhang YJ, Jin XH, Athar M, Santella RM, Bickers DR, Wang ZY.(PubMed)
(100) Resveratrol ameliorates imiquimod-induced psoriasis-like skin inflammation in mice by Kjær TN1, Thorsen K2, Jessen N2, Stenderup K3, Pedersen SB1.(PubMed)
(101) The Unbelievable Smoothie Green Tea and Grape for reduced risk and Treatment of Psoriasis by Kyle J. Norton

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