Types of Musculo-Skeletal disorders in elder(2)
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
7. Low back pain
Epidemiological studiesin human and animal have insisted of pro-inflammatory cytokines as primary mediators of the accelerated bone loss at menopause in which interfering the activation of osteoclasts and stimulators of osteoclastic bone resorption(391).
1. 1. Garlic
Garlic, one of the top food with property on modulation of the pro-inflammatory cytokines associated to postmenopausal bone loss(394) due to aging in reduced production of estrogen. The recent study by the Presidency College, suggested that oil extract of garlic promotes and preserve skeletal health in attenuate bone loss by expression of estrogenic effects through reduced oxidative stress of peritoneal macrophages, lymphocytes and serum interleukins(395) and enhanced intestinal transference of calcium(396).
In ovariectomized rat model, garlic oil in comparison with lovastatin exhibited anti bone loss its reflected onhigher bone densities and higher bone mineral contents(397) as well as induced positively in suppressing ovariectomy-bone resorption(398)..
Turmeric with the similar property as garlic in enhancing immune system fighting against inflammation caused by either free radicals and foreign invasion(399)(400). Used in tradition medicine to relieve menopausal symptoms, the antioxidant also promoted production of bone structural genes, increased the osteoprotegerin to RANKL ratio and supported mineralization more efficiently, according to the Mahidol University(401), as well as reduced trabecular bone loss and prevented deterioration of bone microarchitecture by suppressing the rate of bone turnover(402) probably due to its phytoestrogenic effects(401). DR. Shishodia S and the research team at the The University of Texas M. D. Anderson Cancer Center said " The efficacy, pharmacologic safety, and cost effectiveness of curcuminoids prompt us to "get back to our roots.""(403) due to its effects for treatment of several diseases(403).
1.3. Green tea
Green tea, a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years, is considered as one the top antioxidants and anti inflammatory agent (404)(405). Epidemiological studies suggested that green tea benefited body composition and improved bone microstructure and strength(406), exhibited osteogenic differentiation(407) and reduced risk of osteoporosis(408).
1.4. Shiitake mushrooms
Shiitake mushroom is an edible mushroom with anti inflammatory activity through activated the immune effects and enhance cell resistance to bacterial infections(409).