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Monday, 14 December 2015

Most Common Diseases of elder: The Clinical Trials and Studies of Musculo-Skeletal disorders: Osteoporosis: The miracle of Salmon according herbal and TCM medicine specialist

Kyle J. Norton (Scholar)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. According to a community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home, musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder(2)

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                Osteoporosis

Osteoporosis is defined as a condition of thinning of bone and bone tissues as a result of the loss of bone density over a long period of time. It is a widespread degenerative disease of skeletal joints and often associated with senescence in vertebrates due to excessive or abnormal mechanical loading of weight-bearing joints, arising from heavy long-term use or specific injuries(6).


                               The Treatment

B. In herbal  and traditional Chinese medicine perspective
2. The miracle of Salmon
Salmon is the common name for Salmonidae. They are anadromous, born in fresh water, migrate to the ocean, then travel thousands of miles in the deep sea cold water throughout their life cycle and within to five years returning to the exacted location where they were born to reproduce and die.

Nutrients
1. Protein
2. Omega-3 fatty acids
3. B vitamins
4. Vitamin D
5. Astaxanthin
is a potent antioxidant that stimulates the development of healthy fish nervous systems and enhances the fish's fertility and growth rate.
6. Selenium
7. Tryptophan
8. Magnesium
9. Phosphorus
10. Etc.

Intake of salmon calcitonin, a hormone produced by the thyroid gland of salmon or a synthetic polypeptide of the same sequence found in salmon(360,415) has shown to reduce vertebral crush fractures and bone pain and considered for prevention and treatment of postmenopausal osteoporosis(416). In a randomized trial of  men with idiopathic osteoporosis, nasal spray salmon calcitonin exhibited a significantly pronounced suppression of bone resorption markers by increasing lumbar BMD and reducing bone turnover in men with idiopathic osteoporosis(417) and affecting serum and synovial fluid bone formation and resorption markers in osteoporosis patients(418). Dr Dexue L and Dr. Yueyue Z. said" salmon calcitonin of 50 IU each time, subcutaneous injection 1 time every 3 days, for 3 months is a reasonable solution may be effective for treatment of elderly women with type 2 diabetes and osteoporosis"(419).
Further more, in a randomized, placebo-controlled trial, treatment with salmon calcitonin increased lumbar spine BMD and improved low bone mass and reduced fracture risk in postmenopausal women(420).
The high amount of Omega 3 fatty acid also make salmon of the dietary nutrients for skeleton health including prevention reduced risk of progression of osteoporosis(421).

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies


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References
(1) Prevalence of rheumatic symptoms, rheumatoid arthritis, ankylosing spondylitis, and gout in Shanghai, China: a COPCORD study by Dai SM1, Han XH, Zhao DB, Shi YQ, Liu Y, Meng JM.(PubMed)
(2) Musculoskeletal Disorders in the Elderly by Ramon Gheno, Juan M. Cepparo, Cristina E. Rosca,1 and Anne Cotten(PMC)
(3) Osteoporosis(Life extension)
(4) Hormone and bone by Francisco Bandeira1, Marise Lazaretti-Castro2, John P. Bilezikian3
(5) Growth hormone and bone by Ohlsson C1, Bengtsson BA, Isaksson OG, Andreassen TT, Slootweg MC.(PubMed)
(6) GH and bone--experimental and clinical studies by Isaksson OG1, Ohlsson C, Bengtsson BA, Johannsson G.(PubMed)

(360)
(416) Salmon calcitonin (Miacalcic) nasal spray in prevention and treatment of osteoporosis by Gennari C1.(PubMed)
(417) A randomized trial of nasal spray salmon calcitonin in men with idiopathic osteoporosis: effects on bone mineral density and bone markers by Trovas GP1, Lyritis GP, Galanos A, Raptou P, Constantelou E.(PubMed)
(418) Effects of salmon calcitonin treatment on serum and synovial fluid bone formation and resorption markers inosteoporosis patients by Atbinici H1, Sipahioğlu S2, Aksoy N3, Baykara İ2, Işıkan UE2.(PubMed)
(419) Salmon calcitonin in the treatment of elderly women with type 2 diabetes complicated with osteoporosis by Dexue L1, Yueyue Z2.(PubMed)
(420) Efficacy and safety of oral recombinant calcitonin tablets in postmenopausal women with low bone mass and increased fracture risk: a randomized, placebo-controlled trial by Binkley N1, Bone H, Gilligan JP, Krause DS.(PubMed)
(421) A systematic review of omega-3 fatty acids and osteoporosis by Tonya S. Orchard,1 Xueliang Pan,2 Fern Cheek,3 Steven W. Ing,4 and Rebecca D. Jackson4(PMC)