Tuesday, 12 November 2019

Lycopene Processes Anti OverGrowth of Candida Albicans

By Kyle J. Norton

Fungal infectious disease occur mostly in patients with a weakened immune system characterized by the disease caused by overexpression of specific fungal.

Most common mild fungal skin diseases can induce symptoms of a rash that may go away if the fungal infection is cured.
Candida is a class of yeasts that cause fungal infections worldwide. Under normal conditions, candida does not cause any health issue if they live outside of the body including on the surface of the skin. However, Candida can cause a significant health problem if they grow out of control in the deeper parts of the body, leading to candidiasis.

Candida albicans is a member of a large group of an organism whose cells contain complex structures enclosed within the membranes, including yeast and mold that live among the gut flora in the human mouth and gastrointestinal tract.

Oral candidiasis is an oral condition infected by the fungal C. albicans found mostly in people with a weakened immune system including patients who are taking the immune-suppressive medicine.

Biofilms are microbial communities in which cells stick to each other and often also to a surface.

Symptoms of oral Candida overgrowth include worse in the damp day, persistence drowsiness, lack of coordination, headaches, mood swing, loss of balance, rashes, bad breath, dry mouth, and postnasal drip.

If you experience some of the aforementioned symptoms, please make sure you check with your doctor for early treatment.

There are many risk factors associated with Candida overgrowth including medical conditions that cause weakened immune system, inhalant medicine, low level of stomach acids, and pregnancy.

Some researchers suggested aging due to a weaken the immune system may be one of the major risk factors that cause Candida overgrowth

Dr. Aikaterini Flevari, the lead scientists said, "Candida species remain the most important cause of opportunistic infections worldwide, affecting predominantly patients over 65 years old, while they are considered to be the fourth most common cause of nosocomial bloodstream infections".

And, "The rapidly growing elderly population has specific physiological characteristics, which makes it susceptible to colonization and subsequent infection due to Candida species".

Lycopene is a phytochemical found in tomato in the class of carotenoid, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,

Tomatoes provide about 80% of the lycopene in the world diet. In plants, lycopene protects the host against excessive photodamage and performs various functions in photosynthesis.

On finding a potential compound for the treatment of fungal infection, researchers examined the role of lycopene on C. albicans.

In fungal infection, lycopene exerted potent antifungal effects on pathogenic fungi, including C. albicans in an energy-independent manner.

In Candida albicans induced by fetal bovine serum (FBS) inhibited C, albicans by causing significant membrane damage and blocking the normal budding process.

In other words, the injection of lycopene induced C. albicans apoptosis by the destruction of membrane integrity.

Based on the findings, researchers said, "indicates that lycopene has considerable antifungal activity, deserving further investigation for clinical applications".

Taken altogether, lycopene found in tomato may be considered supplements for the prevention and treatment of C. albicans infection, pending on the confirmation of the larger sample size and multicenter human study.

Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

(1) Damage to the cytoplasmic membrane and cell death caused by lycopene in Candida albicans by Sung WS1, Lee IS, Lee DG. (PubMed)

Treatment of invasive candidiasis in the elderly: a review by Aikaterini Flevari,1 Maria Theodorakopoulou,1 Aristea Velegraki,2 Apostolos Armaganidis,1 and George Dimopoulos. (PMC)

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