Kyle J. Norton
Hypoxia is an urgent medical emergency of deficiency in the amount of oxygen reaching the tissues.
In other words, if your body does not get enough oxygen, you might get hypoxia. The condition has been found to induce brain, liver, and other organs damaged just minutes after symptoms start.
The most common symptoms of hypoxia are associated with a lack of oxygen that reaches the organs and tissues, including changes in the color of the skin, ranging from blue to cherry red, confusion, cough, increased heart rate, rapid breathing, and shortness of breath.
The most common risk factors associated with the onset of hypoxia are damage to the lung due to trauma, medical conditions such as an asthma attack, lung diseases such as chronic obstructive pulmonary disease (COPD), emphysema, bronchitis, pneumonia, pulmonary edema, intake of certain medications that hold back breathing and people with severe anemia.
The most common treatment for hypoxia is to withdraw medications that cause the condition and give additional oxygen to the patient quickly. Almost all patients respond to additional oxygen supplied by a nasal cannula.
Tibetan turnip (Brassica rapa L.), native to the Tibet region, is a medical plant used in Tibet as a “tonic and anti-hypoxia” “heat-clearing and detoxification” and “alleviating fatigue” herbal medications.
In finding a potential compound for the treatment of hypoxia, researchers conducted a joint study led by Zhejiang University on an animal model.
Selected male ICR mice included in the study were assigned to the normoxia group and several hypoxia groups, given sterile water, p-coumaric acid (CA), or dexamethasone orally, once daily for four consecutive days.
Based on the results of the analysis in a hypoxic environment of 9.5% O2,, mice treated with 100 mg/kg body wt CA showed a significantly lower lung water content (LWC), and the protein content of bronchoalveolar lavage fluid (BALF) content than mice in the hypoxia vehicle group.
Where lower lung water content (LWC), and the protein content of bronchoalveolar lavage fluid (BALF)content are the symptoms of the deficient amount of oxygen in the lung.
Moreover, mice treated with CA also protect the lung functioning by showing an intact lung blood gas barrier, increased levels of plasma total NO,
Additionally, levels of preproendothelin-1 (PPET1), associated with vasoconstriction also decreased in the CA treatment group.
More importantly, CA induced the production of occludin, a tight junction protein in maintaining the integrity of the lung epithelial barrier against hypoxia.
Taken together, turnip may be considered herbal medicine for the prevention and treatment of hypoxia, pending the confirmation of the larger sample size and multicenter human study.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) p-Coumaric acid as a prophylactic measure against normobaric hypoxia-induced pulmonary edema in mice by Li Y1, Han J1, Chen Y1, Chen C1, Chu B2, Zhang Y. (PubMed)
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