Kyle J. Norton
Ecchymosis is a discoloration of the skin caused by the bleeding underneath the skin, typically in bruising. Most cases of ecchymosis are results in which the blood vessels near the surface of the skin burst, particularly in the impact of an injury.
In other words, ecchymosis is associated with blood vessel leaks, and the blood accumulates under the skin.
The discoloring of the skin is also involved in the clotting factors, that stop the bleeding so that the tissue starts healing.
The progression of ecchymosis is through a certain stage from red or purple to black or blue
to brown and to yellow.
Certain medications have been found to induce ecchymosis including:
* Blood thinners, such as aspirin or warfarin
*Antibiotics such as cephalexin, cefaclor, and cefuroxime-axetil can cause ecchymosis by inducing low platelet count
* Corticosteroids
According to the study from the University College Hospital, easy bruising tended to be older (61 vs. 52 yrs), on higher daily dosages (1,388 vs. 1,067 micrograms), particularly in the long-term inhaled corticosteroids users.
Most cases of ecchymosis usually heal on their own within two to three weeks. The most common medications used for the treatment of ecchymosis are pain relievers.
Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
With an aim to find a potential compound for the treatment of ecchymosis, researchers examined the effects of bromelain on ecchymosis postprocedure unwanted effects.
The reconfirm the effect of bromelain used internationally by physicians on limited ecchymosis secondary to cosmetic, laser, and surgical skin procedures, researchers reviewed the published literature and provided evidence-based recommendations on bromelain for prevention and treatment of postprocedure ecchymosis.
The search on the computerized bibliographic databases Medline, EMBASE, Scopus, and CINAHL on March 23, 2015, identified 7 clinical trials that study the effect of oral bromelain in the prevention and/or treatment of postprocedure ecchymosis compared to no studies that use topical bromelain for the treatment of ecchymosis.
Based on the results, 5 out of 7 randomized controlled trials reported improvement in postprocedure ecchymosis in the bromelain-treated group.
Taken together, bromelain may be considered a remedy for the treatment of postprocedure ecchymosis, pending the confirmation of the larger sample size and multicenter human study.
Intake of bromelain in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Is There a Role for Arnica and Bromelain in the Prevention of Post-procedure Ecchymosis or Edema? A Systematic Review of the Literature by Ho D1, Jagdeo J, Waldorf HA. (PubMed)
(2) Easy bruising as a side-effect of inhaled corticosteroids by Mak VH1, Melchor R, Spiro SG. (PubMed)
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