Tuesday, 5 September 2023

#Healthyfood #Tomatoes Protect the Tissues of Stomach Against Gastric Injury-Induced by Excessive Alcohol Consumption

Kyle J. Norton

Gastrointestinal injury is an injury associated with the stomach, small bowel, colon, or rectum.
In other words, any damage to the organs of the digestive system caused by blunt or penetrating trauma is considered a gastrointestinal injury.

Gastrointestinal injury caused by blunt trauma in children is uncommon, accounting for less than 1% of all gastrointestinal injuries.

Believe it or not, in children, the most common causes of gastrointestinal injury are caused by a discrete point of energy transfer such as a seatbelt (19%), a handlebar (13%), or a blow from abuse (19%), or other blows and is unique to this population, according to the Children's Hospital.


Depending on the organ damage, patients may experience different symptoms.

In small intestinal injury, patients may have symptoms of pain close to the injured bowel segment, abdominal distension, and diarrhea, ileus, diffuse abdominal pain, nausea, and vomiting.

In large intestinal injuries, patients may have symptoms of persistent focal pain in a trocar site with abdominal distention, diarrhea, and leukopenia.

In gastric/stomach injury, patients May first experience symptoms of nausea, vomiting, blood in the urine, and fever, followed by abdominal pain, tenderness, distension, or rigidity.

In rectal injury, patients may have symptoms of rectal itching, pain, and rectal bleeding.


Tomato is a red, edible fruit, genus Solanum, belonging to the family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.

In finding a potential ingredient for the prevention and treatment of gastrointestinal injury, researchers investigated the transgenic mini-tomato and protection against alcohol-induced gastrointestinal injury.

By examining the function of the epidermal growth factor (EGF) in maintaining the physiological function of the mucosa of the digestive tract, and promoting the healing of the gastric and duodenal ulcers, researchers chemically synthesized a tomato codon preference hEGF gene by Agrobacterium-mediated transformation.

Epidermal growth factor (EGF) has been found to play an essential role in wound healing by stimulating epidermal and dermal regeneration.

According to the radioimmunoassay (RIA),15 days of intragastric gavage (ig) administration of the rhEGF-containing juice of the transgenic tomato could significantly protect mice against alcohol-induced ulceration.

The Ulcer index expressed as a degree of the stomach lesion, also decreased from 42.20 +/- 18.13 to 16.25 +/- 9.57.

In other words, the transgenic tomato protects the integrity of the stomach cell against the insults of excessive alcohol consumption that damage the stomach lining tissues and speeds up ulcer healing

Taken together, tomatoes with rhEGF may be considered a dietary supplement for the prevention and treatment of gastrointestinal injury, pending a large sample size and multicenter human study.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before It's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Transgenic mini-tomato and protection against alcohol-induced gastric injury by Zhi Q1, Wang S, Chai M, Zhang F, Li Q, Li S, Sun M. (PubMed)
(2) Injuries of the gastrointestinal tract from blunt trauma in children: a 12-year experience at a designated pediatric trauma center by Canty TG Sr1, Canty TG Jr, Brown C. (PubMed)

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