Kyle J. Norton
Stroke is a medical condition caused by reduced blood flow to the brain resulting in cell death due to a blocked artery (ischemic stroke) or the leaking or bursting of a blood vessel (hemorrhagic stroke).
In other words, stroke can be caused by either ischemia, due to lack of blood flow, or hemorrhagic, due to bleeding.
A stroke is a medical emergency. Early intervention in most cases can minimize brain damage and potential complications.
Sadly, stroke is one of the most common causes of death worldwide.
In the US, according to statistics, approximately 800,000 people suffer a stroke of which 600,000 of these are first attacks, and 185,000 are recurrent attacks. Nearly three-quarters of all strokes occur in people over the age of 65.
There is a general belief that stroke is an accumulation over a long period of an unhealthy diet with red meat and processed meats in the induction of artery-clogging.
Atherosclerosis associated with the hardening of the arteries caused by the buildup of fatty substances in the arteries can lead to stroke.
In other words, if the blood vessel that feeds the brain is blocked, a stroke occurs.
Some researchers suggested that increased intake of fruits and vegetables such as carrots accompanied with good fats such as salmon, tuna, and mackerel may have a substantial effect in reduced inflammation in the arteries, improved blood flow, and decreased the chance of blood clots.
Not all strokes can lead to permanent brain damage. Some people with a temporary disruption of blood flow to the brain do not result in permanent damage.
Besides aging, smoking, medical conditions such as unmanaged high blood pressure and cholesterol and diabetes, obesity, and physical inactivity are some of the prevalent factors found in stroke patients.
Cruciferous vegetables are a group of vegetables, belongings to the family Brassicaceae (also called Cruciferae) with many genera, and species, and cultivated all over the world in suitable climates for commercial profits, including cauliflower, cabbage, kale, garden cress, bok choy, broccoli, Brussels sprouts, and green leafy vegetables.
In finding a potential remedy for reducing the mortality rate of cardiovascular diseases, researchers examined the therapeutic potential and protective effect of D3T found in cruciferous vegetables for the treatment of ischemic stroke.
The study included selected mice subjected to transient middle cerebral artery occlusion/reperfusion (tMCAO/R) who were administered with vehicle or D3T to evaluate the effect of D3T in cerebral brain injury.
Based on the results of the experiment,
* D3T reduced infarct size, decreased brain edema, lessened blood-brain barrier disruption, and ameliorated neurological deficits.
* D3T suppressed microglia (MG) activation induced by stroke and inhibited peripheral inflammatory immune cell infiltration of CNS in the ischemic brain.
* D3T also exerted a protective effect on ischemic stroke against the induction of oxidative stress by mediating the improved expression of the antioxidant enzyme Nrf2.
Based on the results, researchers said, "D3T confers protection against ischemic stroke, which is mediated through suppression of MG activation and inhibition of CNS peripheral cell infiltration, and that the protective effect of D3T in ischemic stroke is dependent on the activation of Nrf2".
Taken altogether, cruciferous vegetables may be considered functional remedies for protection in ischemic strokes, pending the confirmation of the larger sample size and multicenter human study.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) 3H-1,2-Dithiole-3-thione as a novel therapeutic agent for the treatment of ischemic stroke through Nrf2 defense pathway by Kuo PC1, Yu IC2, Scofield BA1, Brown DA3, Curfman ET2, Paraiso HC4, Chang FL5, Yen JH. (PubMed)
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