Primary glioblastoma is one of the most aggressive cancers that begins within the brain. Cancer may arise as a Grade IV tumor with no evidence.
According to the statistic, the median survival time of primary glioblastoma is approximately 3 months without medical treatment. Glioblastomas represent about 15% of all primary brain tumors.
Conventionally, radiation and chemotherapy are the most common forms of treatment for patients with glioblastoma particularly, in a tumor that cannot be removed with surgery.
The causes of glioblastoma are not identified. However, the increased in age and genetic preposition are the 2 most common risk factors found in patients with the disease.
And, "These germline abnormalities are manifested as either gene polymorphisms or hemizygous mutations of key regulatory genes that are involved either in DNA repair or in apoptosis".
Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belongings to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean.
The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.
On finding a potential compound for the treatment of gliomas, the type of primary brain tumor in adults, researchers examined the effects of Withania somnifera (ashwagandha) on neuronal cell lines.
Taken altogether, Ashwagandha may be considered a functional herb for the prevention and treatment of glioblastoma, pending to the confirmation of larger sample size and multicenter human study.
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Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
(1) Withaferin A and its potential role in glioblastoma (GBM) by Dhami J1, Chang E2, Gambhir SS. (PubMed)
(2) Withania somnifera Suppresses Tumor Growth of Intracranial Allograft of Glioma Cells by Kataria H1,2, Kumar S1, Chaudhary H1,2, Kaur G. (PubMed)
(3) Chapter 8Epidemiology and Outcome of Glioblastoma by Ahmad Faleh Tamimi and Malik Juweid (NCBI)
(4) Inherited predisposition to glioma by Athanassios P. Kyritsis, Melissa L. Bondy, Jasti S. Rao, and Chrissa Sioka. (PMC)