Chronic allergic airways disease (AAD) is a group of the disease characterized by airway inflammation and airway hyperresponsiveness (AHR).
With an aim to discover a potential compound for the treatment of diseases associated with chronic inflammation, researchers examined the ability of bromelain in reducing the inflammation of preexisting asthma via ovalbumin (OVA)-induced murine model of allergic airway disease (AAD).
Furthermore, bromelain also significantly reduced bronchoalveolar lavage (BAL) CD4+ associated and CD8+ T cells d with the T helper 2 (TH2) cells in the promotion of allergic inflammation process without affecting cell numbers in the spleen or hilar lymph node.
In other words, bromelain protects asthma patient against allergic airway inflammation through its strong anti-inflammatory property.
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Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
(1) Bromelain limits airway inflammation in an ovalbumin-induced murine model of established asthma by Secor ER Jr1, Shah SJ, Guernsey LA, Schramm CM, Thrall RS. (PubMed)
(2) Bromelain exerts anti-inflammatory effects in an ovalbumin-induced murine model of allergic airway disease by Secor ER Jr1, Carson WF 4th, Cloutier MM, Guernsey LA, Schramm CM, Wu CA, Thrall RS. (PubMed)
(3) Allergic Airway Disease: More than Meets the IgE? by Jill R. Johnson, Ph.D. and James A. Harker, Ph.D