Scientists may have found a natural alternative for the treatment fo depression according to studies.
Depression is a common and serious psychological illness, affecting physical and mental functions of patients, including the ways patients feel, think and act.
Honey is the miraculous product made by bees using nectar from flowers.
The rich golden liquid is considered one of healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.
Scientists on searching an alternative remedy for the treatment of depression with no side effects examined the effects of honey on several studies through searching the database of online medical literature.
8 studies satisfied the standard criteria and guidelines were chosen, including 2 RCTs of human subjects and 6 animal studies.
The randomized studies suggested that depressed elderly treated with a mix of honey and barely exhibited a significant decrease in depression, stress, and mood disturbances scores compared to the control group.
In menopause women, treatment with honey or a mix of honey and pollens exerted a significant activity in the improvement of the three subscales of the Menopause Rating Scale (MRS) by 68.3% and 70.9%, respectively.
The results also suggested that posttreatment demonstrates a better effect compared to the pretreatment when the mixture of honey was applied.
Furthermore, the application showed similar effects on the serum levels of cholesterol, such as total, HDL, or LDL cholesterol), triglycerides or oestradiol in both groups.
According to the survey returned, participants reported that they observed improvements 3-4 days after the initiation of treatment. On a 10-point taste scale, (1 = very good and 10 = very bad) honey received an average score of 2.3, whereas a honey and pollen mix received an average score of 6.0.
Interestingly, the side effects of exhaustion and edema of lower extremities were reported by some participants and 2 participants were withdrawn from the study due to the taste of the mix of honey with bare powder.
In animal studies, all experiments displayed a positive effect of honey on depression. Some studies also found that honey improves depressive-like behaviors, cognitive function, and symptoms of anhedonia.
Futhermore, honey injection also showed a reduction of anxiety symptoms and improvement of spatial memory.
Moreover, honey alone or a combination of honey and other bee products inhibited MAO enzyme activity in the liver of treated mice.
Where monoamine oxidase A (MAO-A), an enzyme which metabolizes monoamines was elevated in depressed patients.
And, the anti-depressive effects were correlated to the volume of honey intake. In other words, greater improvements were associated with the increased administration of high doses of honey.
In order to reveal more information about honey depression activity, researchers examined
Tualang and Acacia honey in patients with the stress-depression disorder.
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Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
(1) Bee Honey as a Potentially Effective Treatment for Depression: A Review of Clinical and Preclinical Findings by Amira Mohammed Ali1* and Amin Omar Hendawy. (JOJ Nursing and Health Care)
(2) Potential used of Tualang and Acacia Honey in Ameliorating Stress-Depression Disorder: A Preliminary Study by Qamarul Hafiz Zainol Abidin, Nurul Hanani Mohd. Rujhan, Wan Iryani Wan Ismail. (Researcher Gate)
(3) Life stress as potential risk factor for depression and burnout by Author links open overlay panelT.PliegeraM.MelchersaC.MontagbR.MeermanncM.Reuterad. (Science Direct)