Herbal Cascara sagrada processed a bioactive compound emodin may have a potential and profound effect on reducing the risk and treatment of bacterial infection, according to studies.
According to the statistic, infectious diseases caused the death of 9.2 million deaths in 2013 worldwide, represented 17% of all deaths.
Bacterial infection is a result of the battle of the immune system against the multiplication of bacteria in some selected tissue or organ by the pathogens after scaping the assault of white blood cell in the first line of immune defense.
Bacterial infection can be caused by the spread through infected person coughing and sneezing and contact with infected people or contaminated surfaces, food, and water.
Cascara sagrada is a species of buckthorn, genus Rhamnus, belonging to the family Rhamnaceae, native to western North America. The herbal bark has been used in traditional medicine for gastrointestinal support. and it is thought to have a laxative and natural cleansing, etc.
The chemical constituents of Cascara Sagrada include Aloe-emodin, Anthrquinone glycosides (Barbaloin Cascarosides A, B, C and D ChrysaloinFrangul), Chrysophanol, Emodin, Heterodianthrones palmidin A, B, and C, dianthrones, Oxanthrone, Rhein, Tannins, etc.
Researchers on finding a natural ingredient to treat bacterial infection examined the effects of emodin against Methicillin-resistant Staphylococcus aureus (MRSA), a substantial contributor to morbidity and mortality.
In 17 different strains of the bacterium selected to the study, the combined activity of EM and two antimicrobial agents (AM, OX) against all strains resulted in a fractional inhibitory concentrations index (FICI) ranging from 0.37-0.5 and from 0.37-0.75, respectively.
The effect of EM with AM and OX was found to be synergistic or partially synergistic.
The antibacterial activity of Aloe was attributed to the concentration of anthraquinone, aloin in a dose-dependent manner.
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Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, best before it's news, the karate GB daily, etc.,.
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References(1) Synergistic effect of emodin in combination with ampicillin or oxacillin against methicillin-resistant Staphylococcus aureus.by Lee YS, Kang OH, Choi JG, Oh YC, Keum JH, Kim SB, Jeong GS, Kim YC, Shin DW, Kwon DY.(PubMed)
(2) [Relationship between antibacterial activity of aloe and its anthaquinone compounds].[Article in Chinese] by Tian B, Hua YJ, Ma XQ, Wang GL.(PubMed)