Thursday, 10 May 2018

How to Improve Your Digestive Functioning Naturally, MEDLINE Studies Suggest

Kyle J. Norton

Fennel may have a therapeutic and enhanced effect in improve digestive system in absorbed nutrients and fluids from foods intake, some scientists suggested.

The result of this efficacy was published online by several respectable institutes, including the University of Illinois at Chicago and Afyon Kocatepe University.

Fennel (Foeniculum vulgare) is a plant species of genus, belongings to Apiaceae (Umbelliferae), native to the Mediterranean, used in traditional and herbal medicine as warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS,...

1. Carbohydrates
2. Fiber
3. Protein
4. Thiamine (Vitamin B1)
5. Riboflavin (Vitamin B2)
6. Niacin (Vitamin B3)
7. Pantothenic acid (B5)
8. Vitamin B6
9. Folate (Vitamin B9)
10. Vitamin C
11. Calcium
12. Copper
13. Iron
14. Magnesium
15. Molybdenum
16. Phosphorus
17. Potassium
18. Zinc
19. Etc.

According to the study, researchers set out a criteria and guideline to investigate the effect of fennel in gram-negative bacterium Helicobacter pylori (HP), the microorganisms has been associated with the development of gastritis and peptic ulcer disease to confirm the theory of used in traditional medicine fennel to treat a wide range of ailments, including gastrointestinal (GI) disorders such as dyspepsia, gastritis and peptic ulcer disease (PUD), application of methanol extracts of botanicals with a MIC of 50 microg/mL included Achillea millefolium, Foeniculum vulgare (seed), exerted a significantly inhibitory effect against all susceptibility of 15 HP strains.

These results suggested that injection of fennel displays a potential effect in balanced the ratio of micro organisms in the gastrointestinal tract, thus improving the function in absorbed and distributed nutrients to the body.

These properties reassured the herbal medicine used in practice for treatment of numbers symptoms of digestive disorder.

Furthermore, in animal model with rat induced gastric lesions induced by injection of ethanol, application of aqueous extracts of Foeniculum vulgare (FVE) showed a strong activity in inhibited the ulcerogenic expression through its antioxidant activities..

In observation of the efficacy of 60 minutes pre administration of the doses of fennel extracts at 75, 150 and 300 mg/kg, with famotidine, histamine H₂ receptor antagonist with function to inhibit stomach acid production at the dose of 20 mg/kg, before injection of ethanol, researchers found that
* Pre treatment of all doses exert significant gastric protective effects in reduced injure and damage caused by injection of ethanol.

* Fennel extract demonstrates a theurateutic activity linearly in compared to other doses and control at dose of 300 mg/kg 

* These activities was associated to reduce the malondialdehyde (MDA) levels, a marker in expression of severe levels of oxiadive stress.

Additional analysis, also suggested that fennel stimulated gastro-protect effect through its antioxidants and facilitated production of antioxidants in the body tissues in inhibited the over expression of free radicals, thus maintaining the ratio of micro organisms in the digestive tract and its functioning.

After, taking into account of other co and con founders, researchers also suggested that the results in part may also be attributed to antioxidant in ameliorated lipid peroxidation.

The above differentiation were supported by the joint report lead by the Joint Keio University, in the investigation of fennel properties in associated to functional dyspepsia (FD), a functional gastrointestinal disorder characterized by persistent or recurrent postprandial upper abdominal discomfort and epigastric pain.

Truly, delayed gastric emptying and impaired gastric accommodation was found to play important roles in the development of FD. 

Anethole (1-methoxy-4-((E)-propenyl)-benzene), a major component of fennel essential oil, in rodents exerted a huge effect in improved clonidine-induced delayed gastric emptying, orally.

Also, application of fennel oil plus Anchu-san (a Japanese herbal medicine containing anethole)  demonstrated an important activity in reduced risk of functional dyspepsia (FD) through restoring the delayed gastric emptying.

In other words,  anethole processes a gastro protective efficacy through stimulating gastric accommodation. 

Taken together, whole fennel, fennel essential oil and its bioactive compound anethole may be used as secondary application in reduced risk and treatment of digestive disorder.

Adding a portion of fennel in your diet may improve the digestive function in absorption nutrients and fluids from the food intake.

However, intake of supplement should be taken with extreme care as overdose may cause acute liver toxicity.

Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

(1) In vitro susceptibility of Helicobacter pylori to botanical extracts used traditionally for the treatment of gastrointestinal disorders by Mahady GB1, Pendland SL, Stoia A, Hamill FA, Fabricant D, Dietz BM, Chadwick LR.(PubMed)
(2) Beneficial effects of Foeniculum vulgare on ethanol-induced acute gastric mucosal injury in rats by Birdane FM1, Cemek M, Birdane YO, Gülçin I, Büyükokuroğlu ME.(PubMed)
(3) Anethole restores delayed gastric emptying and impaired gastric accommodation in rodents by Asano T1, Aida S2, Suemasu S2, Mizushima T3.(PubMed)

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