People with light complexion and lots of sun exposure over the years are found to associate with higher prevalent risk.
Age spot may also be caused by hormone imbalance in induction of increased production of melanin, which is responsible for darkening the skin.
Green tea, is a precious drink processed numbers of health benefit and known to almost everyone in Asia and Western world.
In the investigation of Epigallocatechin gallate (EGCG), used as a constituent of cosmetic products, researchers found that applicationg EGCG exerts a significant effect as an antioxidant in exhibited anti-pigmentation properties.
Through measuring hyaluronic acid synthase (HAS) and hyaluronidase (HYAL) gene expression, EGCG also promoted skin hydration, through increased the expression of natural moisturizing factor-related gene, including Hyaluronan synthase (HAS)-1, and (HAS)-2.
HA synthase enzymes (HAS) amolescule with function of synthesized hyaluronan (HA) plays an essential role in protected skin fibroblasts against apoptosis, due to environment stress exposure.
Melanin produced in melanocytes, under exposure UVB irradiation with an aim to protect skin cells aganist UVB radiation damage.
HaCaT widely used in scientific research of epidermis, is a spontaneously immortalized human keratinocyte cell line isolated from adult human skin.
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Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
(1) Skin Protective Effect of Epigallocatechin Gallate by Kim E1, Hwang K2, Lee J3, Han SY4, Kim EM5, Park J6, Cho JY7.(PubMed)
(2) Green Tea Makes Polyphenol Nanoparticles with Radical-Scavenging Activities by Xiang S1, Yang P1, Guo H2, Zhang S1, Zhang X1, Zhu F1, Li Y1.(PubMed)
(3) Melanogenesis Inhibitory and Antioxidant Effects of Camellia oleifera Seed Oil by Chaikul P1,2, Sripisut T1,2, Chanpirom S1,2, Sathirachawan K1, Ditthawuthikul N1,2.(PubMed)