Sunday, 13 October 2019

The 54 Health Benefits of Tomato and Counting, According to Scientific Studies

By Kyle J. Norton

Tomato is red, edible fruit, genus Solanum, belonging to family Solanaceae, native to South America. Because of its health benefits, tomato is grown worldwide for commercial purposes often in the greenhouse.
1. How to Maintain A Healthy Skin, Naturally and Permanently, PubMed Studies Find
2. Tomatoes EnhanceYour Immunity Naturally, US National Library of Medicine Studies Suggest
3. How to Have a Perfect Breath and Optimal Oral Health Naturally
4. Tomatoes, The Vegetables Which Normalize the Blood Pressure in Hypertensive Patients
5. The Easy Way to Prevent Osteoporosis That No One Wants to Tell --Eat Your Tomato, Scientists Say
6. Tomato Improves Sleep Quality by Enhancing Levels of Melatonin
7. Tomato, the Anti Hyperlipidemia Functional Food for Type 2 Diabetics
8. Whole Food Tomatoes, Protects the Aging Vision Against Age-related Macular Degeneration (AMD)
9. Whole Food Tomato Protects the Lung Against Pulmonary Oxidative Stress
10. Whole Food Tomato Protects Diabetics Against Complications Caused by Oxidative Stress
11. Cooked Tomatoes, Protect the Blood Vessels Against the Onset of stroke
12. Whole Food Tomato and Its Bioactive Compound Lycopene Protect the Obese Patients Against Complications
13. Tomatoes Normalize the Blood Glucose Against Hyperglycemia on Diabetes
14. Whole Food Tomatoes, the Natural Treatment of Hypercholesterolemia
15. Whole Food Tomatoes Protect Your Stomach Against Gastric Cancer in Human Studies
16. Whole Food Tomatoes, the Best to Prevent and Treat Metabolic Syndrome, According to Human Studies
17. Whole Food Tomato, The Potent Inhibitor Against Platelet Aggregation in Vitro and Vivo.
18. Whole Food Tomato Modulates Hormone Angiotensin Against the Onset of Heart Disease
19. Tomato the Potent Anti Digestive-Tract Cancer Functional Food, Human Studies Show
20. Whole Food Tomato Inhibits Gene and Factors Associated with Obesity Complications in Vivo
21. Tomatoes Protect the Liver Against Non-alcoholic Steatohepatitis in Vivo
22. Healthy Food Tomatoes' Lycopene Inhibits Primary Lung Cancer
23. Whole Food Tomato Promotes the Lung Function in Human Trials
24. Whole Food Tomato Protects Your Heart Against Cardiovascular Diseases
25. Whole Food Tomato Improves Glucose Tolerance in Diabetics in Vivo
26. Whole Food Tomato Suppresses the Onset of Pulmonary Diseases
27. Whole Food Tomato Normalizes Hepatic Markers Against Liver Damage and Injury
29. Healthy Food Tomato, A Potential, and Natural Prevention and Treatment of Cancer
30. Whole Food Tomato Protects the Tissues of Stomach Against Gastric Injury
31. Whole Food Tomato, the Best Anti-Inflammatory Remedy with No Side Effects
32. Tomato Inhibits the Onset of Non-alcoholic Steatohepatitis
33. Herbal Tomato Promotes Immunomodulatory Activity Against the Onset of Colitis In Vivo
34. Whole Food Tomato Promote the Ratio of Gut Microbiota For Optimal Health
35. Healthy Food Tomato Inhibits Hepatic Steatosis in Vivo
36. Whole Food Tomato Protects the Obese Against Obesity-Related Co-Morbidities
37. Whole Food Tomato Balances the Ratio of Intestinal Microbiomes in the Gut
38. Whole Food Tomatoes prostate (PC3) Protects The Cells of Prostate Gland Against Prostate Cancer, Studies Show
39. Healthy Food Tomato Protects The Integrity of Neurons Against Neurological Disorders in Vivo
40. Whole Food Tomato Modulates Immune Function to the Body Needs
41 Healthy Food Tomato Induces Cytotoxicity Against Cancer Cells
42. Whole Food Tomatoes, the Best Antioxidant Functional Food
43. Tomato Protects the Ovary Against Cell DNA Alternation
44. Broccoli and Tomato Inhibits Elevated Hormone Resistin Associated with Insulin Resistance
45. Whole Food Tomato, the Anti-Insulin Resistance Natural Remedy
46. Whole Food Tomato Apoptoses Liver Cancer Better Than of Doxorubicin and Camptothecin in Vitro
47. Cooked Tomato's Lycopene Protects Protein, Lipid and Cell Damage Against Oxidative Stress in Human Studies
48. Healthy Food Tomato, the Natural and Potential Anti-Inflammatory Remedy
49. Tomato's Phytochemical Carotenoids Block the Onset of Colorectal Cancer in Patients with DICER1 rs3742330 Genotypeancer
50. Tomatoes Kill Bacterial Staphylococcus Aureus Against the Onset of Pneumonia
51. Tomato/Lycopene the Anti Cancers Functional Food
52. Whole Food Tomato Inhibits Colorectal Cancer in Vitro and Vivo
53. Whole Food Tomatoes, Kill Breast Cancer in Vitro
54. Tomato Inhibits the Onset and Progression of Non-Alcoholic Fatty Liver Disease (NAFLD)
55. Healthy Food Tomatoes inhibits the Growth and Progression of Liver Cancer in Vivo
and Counting

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Turmeric Protects the Heart Muscles Against Cardiotoxicity in Vivo

By Kyle J. Norton

Cardiac toxicity is a condition in which the heart has been damage to some extent caused by harmful chemicals, including toxins induced by the treatment of chemotherapy.

Cardiac toxicity reduced heart muscle function to pump blood and is a leading cause of heart failure.

Long term intake of certain medication and people who are under treatment of chemotherapy have been found in most cases of cardiotoxicity.

Dr. Danúbia Silva dos Santo and colleagues in the examination of doxorubicin (DOX) in the risk of cardiotoxicity wrote, "Doxorubicin (DOX) is among the most effective anticancer agents ever developed. DOX has been used mainly for the treatment of breast cancer, solid tumors in children, soft tissue sarcomas, and aggressive lymphomas".

However, researchers continued, "the use of DOX may have dose-dependent cardiotoxic effects that generate changes in myocardial structure, which can develop into severe and irreversible cardiomyopathy".

Additionally, human immunodeficiency virus (HIV) infection, genetic preposition, a malignant disease associated with the amyloid deposited on the heart or other organs, high blood pressure, untreated hyperthyroidism, and vitamin b2 deficiency are some of the most prevalent factors found in patients with cardiotoxicity.

Depending on the cells of the areas of the heart that have been damaged, cardiac toxicity includes cardiomyopathy, myocarditis, pericarditis, acute coronary syndromes, and congestive heart failure.

Most common symptoms of cardiotoxicity are associated with not enough blood circulation in the body such as tiredness and fatigue, a long-term (chronic) cough, shortness of breath, floating due to the enlarged heart muscle, abnormal heart or lung sounds and swelling in your hands, feet, or unusual weight gain.

Conventionally, treatment of cardiotoxicity is totally depending on the types of the disease including
Beta-blockers, ACE inhibitors induce (widen) the arterial dilation and improvement of the blood flow and diuretics.

Turmeric is a perennial plant in the genus Curcuma, belongings to the family Zingiberaceae, native to tropical South Asia.


The herb has been used in traditional medicine as an anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.

On findings a potential compound for the treatment of heart disease associated with chemical toxicity, researchers examined the effect of nanomicelle curcumin on BPA-induced subchronic cardiotoxicity in rats.

The selected rat was randomly divided into 6 groups including control, nanomicelle curcumin (50 mg/kg, gavage), BPA (50 mg/kg, gavage), nanomicelle curcumin (10, 25, and 50 mg/kg) plus BPA for 4 weeks.

Based on the results of assays, BPA significantly induced cardiac injuries including focal lymphatic inflammation, nuclear degenerative changes, and cytoplasmic vacuolation associated with inflammation.

Compared to the control, BPA  caused the increased body weight, systolic and diastolic blood pressures, and cardiac stress observed by the increased levels of malondialdehyde and myocardial cell wall injury observed by the creatine phosphokinase-MB level.


Furthermore, levels of antioxidant enzymes in the rat also such as glutathione content was also decreased by the BPA injection.

The cardiac injury in BPA also observed by the electrocardiographic graph, RR, QT, and PQ intervals.

BPA also found to induce increased expression of genes associated with cardiac cell apoptosis and inhibited genes expression of cardiac cell survival.

However, nanomicelle curcumin (50 mg/kg) administration significantly reduced the BPA toxic effects induced the aforementioned parameters in rat heart tissue.

Based on the findings, researchers said, "The results provide evidence that nanomicelle curcumin showed preventive effects on subchronic exposure to BPA induced toxicity in the heart tissue in rats".

Taken altogether, turmeric processed abundantly bioactive compound curcumin may be considered supplements for the prevention and treatment of cardiotoxicity, pending to the confirmation of the larger sample size and multicenter human study.

Intake of turmeric in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) The protective activity of nanomicelle curcumin in bisphenol A-induced cardiotoxicity following subacute exposure in rats by Valokola MG1, Karimi G1,2, Razavi BM1,3, Kianfar M1, Jafarian AH4, Jaafari MR5, Imenshahidi M. (PubMed)
(2) Doxorubicin-Induced Cardiotoxicity: From Mechanisms to Development of Efficient Therapy By Danúbia Silva dos Santos and Regina Coeli dos Santos Goldenberg

Cabbage Preserves the Mitochondrial Function Against Oxidative Stress

By Kyle J. Norton

Mitochondria are the cell that converts the food molecules into the energy for the body tissues' needs. Mitochondria produce 90 percent of the energy for the body function.

Mitochondrial dysfunction is a condition affecting the organelles that generate energy for the cell.

Genetically, the genetic proposition has been found to alter the process of mitochondria in converting oxygen and food to energy in some people.

Acquired mitochondrial dysfunction caused by the long-term use of certain medications such as Metformin, medical conditions such as mitochondrial encephalomyopathy or infection and environmental influences, such as xenochemicals, leading to less and less energy generated within the cells.
Acquired mitochondrial dysfunction has been found in patients with Alzheimer’s disease, muscular dystrophy, Lou Gehrig’s disease, diabetes, and cancer.

Most common symptoms of mitochondrial dysfunction include poor growth, muscle weakness, muscle pain, low muscle tone, exercise intolerance, vision and/or hearing problems
learning disabilities, delays in development, mental retardation depending on the location of the infected cells.

Diseases associated with mitochondrial dysfunction include Autism, autism-like features Heart, liver or kidney diseases, seizures, strokes, severe developmental delays, inability to walk, and dementia.

Conventionally, treatments of mitochondrial dysfunction are totally depending on the causes of the disease.

Dr. Sreenivas Avula, the lead scientist wrote, "Classification of therapies for mitochondrial disorders has evolved from the empirical therapies targeting residual respiratory chain to acting at the molecular level to alter the expression of mutated mtDNA genes within the cell nucleus".

And,  " ...in the future, treatment strategies may employ a combination of pharmacological treatments that have undergone rigorous clinical trials targeting OXPHOS, as well as newer strategies at the molecular level".

Cabbage is a species of Brassica oleracea belongings to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The veggie has a short stem of which is crowded a mass of leaves, usually green but in some varieties, it may be red or purplish.
With an aim to find a natural food for the prevention of oxidative stress in the progression of cardiac diseases, researchers examined the effect of cabbage extract on mitochondrial dysfunction in H9c2 cardiomyoblasts.

According to the tested differentiation, the administration of cabbage extract protected the mitochondria against H2O2-induced cell death without eliciting the cytotoxic effects.

Furthermore, cabbage extract enhanced the expression of antioxidant proteins (SOD-1, catalase, and GPx) against ROS production.

Moreover, the extracts also stimulating the protein associated with cell survival by inhibiting apoptotic responses in oxidative stress-exposed H9c2 cells.

More precisely, cabbage extract preserved mitochondrial functions upon oxidative stress. 

Based on the results, researchers wrote, "These findings reveal that cabbage extract protects against oxidative stress and suggest that it can be used as an alternative therapeutic strategy to prevent the oxidative stress in the heart".

Taken altogether, cabbage processed abundantly SFN may be considered a remedy for the prevention and treatment of mitochondrial dysfunction in the initiation of heart disease, pending to the confirmation of the larger sample size and multicenter human study.

Intake of SFN in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Cabbage (Brassica oleracea var. capitata) Protects against H2O2-Induced Oxidative Stress by Preventing Mitochondrial Dysfunction in H9c2 Cardiomyoblasts by Yang DK. (PubMed)
(2) Treatment of Mitochondrial Disorders by Sreenivas Avula,1 Sumit Parikh, MD,1 Scott Demarest, MD,2 Jonathan Kurz, MD,2 and Andrea Gropman, MD. (PMC)

Saturday, 12 October 2019

Kale Supplement, the Potential Treatment of Hypertension

By Kyle J. Norton

Hypertension or high blood pressure, a condition associated with the cluster of metabolic syndrome is a medical condition associated with abnormally high blood pressure.

Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood and changes constantly depending on activity. However, persistent hypertension due to poor management over time can lead to cardiovascular disease.

According to the statistics provided by the American Heart Association., nearly half of all adults in the United States are living with high blood pressure or 1 in 3 American are hypertensive.

Hypertension is the leading risk factors of heart disease and stroke in the US.

Cardiovascular diseases (CVD) including heart disease and stroke are a class of conditions associated with the dysfunction of the arteries and heart, affecting the heart functioning.

According to the statistics provided by the CDC, heart disease is the leading cause of death for both men and women. Men are associated with 1/2 of the deaths due to heart disease in 2015 were in men, comapred to women.

Believe it or not, more than 63,000 Americans die from heart disease each year or 1 in every 4 deaths are caused by heart disease.

Most common prevalent factors associated with the hypertension onset are family history, aging, being male, being overweight or obese, ethnicity, physical inactivity, unhealthy diet and medical condition such as chronic kidney disease.

Excessive alcohol drinking is also one of the major causes besides obesity in elevating the syndrome onset.

Depending on the levels of blood pressure, most people with mild hypertension are assymptomatic. However, unmanaged high blood pressure can induce complication of heart attack or stroke, heart failure, weakened and narrowed blood vessels, metabolic syndrome and trouble with memory or understanding,

Conventionally, blood pressure medications have been found to prevent many deaths from heart disease and stroke over the past 30 years, however, long-term intake of such medications have caused many side effects such as damaging the kidney.

Some researchers suggested by making changes to lifestyle, maintaining ideal weight and diet with low salt, you could do just fine without the drugs.

Dr. L. J. Beilin wrote, "Lifestyle factors are critical determinants of blood pressure levels operating against a background of genetic susceptibility. Excess body fat is a predominant cause of hypertension with additive effects of dietary salt, alcohol, and physical inactivity."
And "Controlled trials in hypertensives show blood pressure lowering effects of supplemental potassium, fiber, n-3 fatty acids, and diets rich in fruit and vegetables and low in saturated fats".

With an aim to find a natural food for the prevention and treatment of hypertension, researchers examined the effect of daily supplementation of kale juice can modulate blood pressure (BP).

The study included 84 subclinical hypertensive patients with systolic BP over 130 mmHg or diastolic BP over 85 mmHg who received 300 ml/day of kale juice for 6 weeks.

According to the blood samples obtained on 0-week and 6-week, kale supplements showed a significantly decreased systolic and diastolic blood pressure in all patients regardless of their GSTM1 or GSTT1 polymorphisms.

According to the joint study led by the Isfahan University of Medical Sciences, GSTT1 and GSTM1 gene increases the arterial pressure; hence, it can predict the susceptibility to cardiovascular disease.

In other words, kale supplements inhibited the hyperactive parameters without being affected by the gene expression of GSTM1 or GSTT1 polymorphisms.

Furthermore, kale supplement exerted no effect on plasma lipid profiles of patients with GSTM1-null and GSTM1-present genotypes.

More importantly, the supplement also increased plasma HDL-C and lowered LDL-C in the GSTT1-present type, while blood glucose was decreased only in the GSTT1-null genotype.

Based on the findings, researchers suggested, kale processes a strong effect in lowering the blood pressure through other mechanisms, regardless of GSTT1 and GSTM1 gene types.

Taken altogether, kale juice may be considered supplements for the prevention and treatment of hypertension, pending to the confirmation of the larger sample size and multicenter human study.



Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) The effect of glutathione S-transferase M1 and T1 polymorphisms on blood pressure, blood glucose, and lipid profiles following the supplementation of kale (Brassica oleracea acephala) juice in South Korean subclinical hypertensive patients by Han JH1, Lee HJ1, Kim TS2, Kang MH. (PubMed)
(2) Association of GSTT1 and GSTM1 polymorphisms with blood pressure: A Bayesian modeling of continuous data by Laleh Rafee, Mahsa Abedini,1 Shaghayegh Haghjooy Javanmard, Nizal Sarrafzadegan,2 and Marjan Mansourian. (PubMed)
(3) Lifestyle and hypertension by L. J. Beilin, I. B. Puddey, V. Burke. (the American Journal of Hypertension)

Turmeric Gobbles Up Plaques Against the Onset of Atherosclerosis

By Kyle J. Norton

Cardiovascular diseases (CVD) are a class of conditions associated with the dysfunction of the arteries and heart, affecting the heart functioning.

According to the statistics provided by the CDC, heart disease is the leading cause of death for both men and women. Men are associated with 1/2 of the deaths due to heart disease in 2015 were in men, comapred to women.

Believe it or not, more than 63),000 Americans die from heart disease each year or 1 in every 4 deaths are caused by heart disease.

Atherosclerosis is a condition caused by long-term plaques built-up on the wall of the arteries. Over time, continued plaques accumulation can lead to cardiovascular disease.

In other words, narrowing the arteries due to plaques accumulation is a major cause of heart disease and stroke.

Plaque is made up of fat, cholesterol, calcium, and other substances found in the blood.

Most common symptoms found in patients with antiatherosclerosis are involved in the reduce blood flow to the body, including chest pain or angina, pain in the leg, and arm, shortness of breath and fatigue and confusion.

According to Dr. Roma Pahwa and colleagues, atherosclerosis cause approximately 50% of all deaths in westernized society associated with the inflammation in the arteries involved in the accumulation of cholesterol in the bloodstream.

Epidemiologically, the most common risk factors of atherosclerosis are unhealthy blood cholesterol levels associated with high levels of bad and low levels of good cholesterol, high blood pressure, smoking, insulin resistance, diabetes, overweight or obesity, physical inactivity.

Some researchers suggested that the promotion of a high-fat diet that induces widespread obesity in the Western world may be one of the major culprits that cause atherosclerosis.

Dr. Lovren F and colleagues wrote, "Obesity is a multifactorial chronic disease characterized by an accumulation of visceral and subcutaneous fat, which leads to a predisposition toward cardiometabolic diseases".

And, " A plethora of mechanisms, including abnormalities in lipid metabolism, insulin resistance, inflammation, endothelial dysfunction, adipokine imbalance, and inflammasome activation have been suggested to underlie the relationship between obesity and atherosclerosis.".

Turmeric is a perennial plant in the genus Curcuma, belongings to the family Zingiberaceae, native to tropical South Asia.

The herb has been used in traditional medicine as an anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.

On findings a potential compound for the treatment of multiple sclerosis (MS), researchers examined the efficacy of supplementation with curcumin on reducing intestinal cholesterol absorption in animal models.

The study included high-fat diet-fed apolipoprotein E knockout (ApoE-/-) mice prevented atherosclerosis fed a high-fat diet supplemented with or without curcumin (0.1% w/w) for 16 weeks.

Based on the tested differentiation, the curcumin treatment group showed not only a reduced cholesterol accumulation in the aortas by 56% but also lowered plasma total cholesterol and low-density lipoprotein cholesterol levels comapred to the non-curcumin group.

Furthermore, curcumin supplementation group also demonstrated a reduced risk of atherosclerotic lesions by 45%.

Moreover, the efficacy of the anti antiatherogenic effect of curcumin was associated with a significant decrease in intestinal cholesterol absorption by 51% by inhibiting the intestinal gene expression of Niemann-Pick C1-like 1 involved in cholesterol uptakes.

Collectively, researchers said, "These findings support the hypothesis that curcumin supplementation reduces intestinal cholesterol absorption and prevents atherosclerosis in high-fat diet-fed ApoE-/- mice".

And " Curcumin affords a potent antiatherogenic action by inhibiting intestinal cholesterol absorption in the mouse".

Taken altogether, turmeric processed abundantly bioactive compound curcumin may be considered supplements for the prevention and treatment of atherosclerosis, pending to the confirmation of the larger sample size and multicenter human study.

Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Curcumin as a potential modulator of M1 and M2 macrophages: new insights in atherosclerosis therapy by Momtazi-Borojeni AA1,2, Abdollahi E3,4, Nikfar B5, Chaichian S6,7, Ekhlasi-Hundrieser M. (PubMed)
(2) Supplementation with curcumin inhibits intestinal cholesterol absorption and prevents atherosclerosis in high-fat diet-fed apolipoprotein E knockout mice by Zou J1, Zhang S2, Li P2, Zheng X2, Feng D. (PubMed)
(3) Atherosclerosis by Roma Pahwa; Ishwarlal Jialal. (NCBI)
(4) Obesity and atherosclerosis: mechanistic insights by Lovren F1, Teoh H2, Verma S. (PMC)

Friday, 11 October 2019

Bromelain Improves the Symptoms and Quality of Life in Patients with Cystic Fibrosis

By Kyle J. Norton

Cystic fibrosis (CF) is a genetic preposition that leads to diseases mostly in the lungs in children and young adults.

Most cases of CF has been found to cause persistent infection in the lungs, leading to the destruction of lung tissues and reduced lung function, depending on the severity of the condition.

Most common complication of CF is difficulty digesting fats, proteins and nutrient absorption, progressive lung damage caused by ongoing infections and chronic low-grade inflammation and CF-related diabetes.

According to statistics provided by the Canadian Cystic Fibrosis Foundation, approximately 1 in every 3,600 children born in Canada has CF.

In age perspective,
* 60% of patients are diagnosed in the first year of life, and 90% by 10 years of age.

* More than 47% of all Canadians with CF are over the age of 18 years.

* As of 2002, the median age of survival of Canadians with CF is 37 years of age.

Most common symptoms of CF are persistent cough with productive thick mucous, wheezing and shortness of breath,  frequent chest infections, weight loss or failure to gain weight, infertility in men and decreased fertility in women.

Conventionally, as of today, there is no cure for CF. Medications are focusing on reducing symptoms and improving quality of life, including
* Antibiotics for the treatment of lung infections.

* Anti-inflammatory medications to protect the lung airways.

* Medication to reduce cough up  the mucus

* Inhaled medications to keep your airways open by relaxing the muscles around your bronchial tubes

* Medication to help the digestive tract in absorbing nutrients

Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, and muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.

On finding a natural compound for the treatment of cystic fibrosis, researchers compared with identical capsules half filled with mini-tablets of a new high lipase preparation in a randomized double-blind crossover study in children with cystic fibrosis.


All children participated in the study received his/her usual number of capsules and the same dose of lipase during each period of the study. 

According to the results from the 18 children completed the study, pancreatic enzyme applied in the high lipase preparation showed fewer gastrointestinal symptoms compared to the low lipase group.

Compared to the baseline, pancreatic enzyme group showed a significant improvement in fat absorption and reduction in fecal fat output.

Fecal energy loss was also improved in the treatment group.

Based on the findings, researchers at the St James's Hospital wrote, " (The) half filled capsules of the new high lipase preparation are more effective than the standard preparation and it is likely that filled capsules would allow patients to use fewer than half the number of pancreatic enzyme capsules".

Taken altogether, bromelain may be considered supplements for the prevention and treatment of symptoms of cystic fibrosis, pending to the confirmation of the larger sample size and multicenter human study.

Intake of bromelain in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Gut inflammation in children with cystic fibrosis on high-dose enzyme supplements by Croft NM1, Marshall TG, Ferguson A. (PubMed)
(2) A double blind lipase for lipase comparison of a high lipase and standard pancreatic enzyme preparation in cystic fibrosis by Bowler IM1, Wolfe SP, Owens HM, Sheldon TA, Littlewood JM, Walters MP. (PubMed)

Herbal Ashwagandha Reduces the Risk of Skin Cancer

By Kyle J. Norton

Skin, a large organ in the human not only acts as a barrier to protect the internal organs against the invasion of the foreign pathogen, but also protects the body against mechanical impacts and pressure, variations in temperature, radiation, and chemicals.

Skin cancer is a medical condition associated with irregular cell growth in the skin tissues.

Most cases of skin cancer start in the cells on the surface of the outermost inner lining tissue before penetrating into deeper layers.

After growing in size at the advanced stage, by penetrating into deeper layers of the infected tissue, the cells of the tumor may travel a distance away to infect other healthy tissue and organs through blood and fluids circulation, leading to secondary metastasis of secondary breast, lung, and colon tumor.

Believe it or not, more people are diagnosed with skin cancer each year in the U.S. than all other cancers combined. As of today, there are 58 million American are living with skin cancer.

Approximately, 1 in 5 Americans will develop skin cancer by the age of 70. The 5-year survival of among all people with melanoma of the skin is 92% compared to 100% of the localized skin cancer.

If you have experienced some of the symptoms such as a sore that doesn't heal or comes back after healing, a pale white or yellow flat areas that look like scars, raised and scaly red patches, small, smooth and shiny lumps that are pearly white, pink or red, a pink growth with raised edges and indents in the center and a growth that has small blood vessels on the surface of the skin, you may be on the early stage of skin cancer, please check with your doctor immediately.

Dr. Epstein JH. wrote, "Nonmelanoma skin cancers, like most malignancies, increase in incidence with increasing age. However, in general, they are not due to the aging process but are primarily due to solar radiation".

And, "genetic disease xeroderma pigmentosum support the concept that such damage, if not repaired, will lead to cancer formation. It also has been suggested that unrepaired damage to deoxyribonucleic (DNA) and other macromolecules is at least in part responsible for the aging process in general".
On finding a potent compound for the treatment of cancer, researchers examined the Withania somnifera (Ashwagandha) chemopreventive potential in a chemically-induced skin carcinogenesis mouse model.

According to the tested analysis, WA significantly suppressed skin tumor formation by suppressing cell proliferation.

Furthermore, carcinogen-induced the increase of acetyl-CoA carboxylase 1 (ACC1) associated with cancer metastasis was also blocked by application of WA.

Additionally, in melanoma cells, WA also suppressed the expression levels of ACC1. 

Based on the findings, researchers said, "withaferin A may have potential in chemoprevention and ACC1 may serve as a critical target of WA".

Taken altogether, Ashwagandha may be considered a functional herb for the prevention and an adjunct therapy combined with the primary medicine for the treatment of skin cancer in breast cancer patients, pending to the result of larger sample size and multicenter study



Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You  How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Withaferin A suppresses the up-regulation of acetyl-coA carboxylase 1 and skintumor formation in a skin carcinogenesis mouse model by Li W1,2, Zhang C1,3, Du H1,4, Huang V1, Sun B1, Harris JP1, Richardson Q1, Shen X5, Jin R6, Li G6, Kevil CG5, Gu X5, Shi R7, Zhao Y. (PubMed)
(2) Photocarcinogenesis, skin cancer, and aging by Epstein JH. (PubMed)