Tuesday, 10 October 2023

#Onion's Ethyl Acetate #Extract Exerts a Strong #Antibiotic-Like Activity, Researchers Suggest

Kyle J. Norton

Infection is a medical condition that can acute or chronic. Acute infection is sudden inflammation that occurs in a short period of time accompanied by a relatively brief period of symptoms.
Most cases of acute infection can be solved within days as the infectious agents are destroyed by the host immune system.

Chronic infection is the condition that lasts for a long period of time with the difficulty of clearing. Most cases of chronic infection are latent or slow infections that last the life of the host.

Antibiotics are medicines that inhibit the growth of or destroys microorganisms, including the popular penicillin or its derivatives

The bacterial infection is the infection caused by bacteria. Most cases of bacterial infection are treated with antibiotics. However, bacteria are very adaptable, and overuse of antibiotics has made many of them resistant to antibiotics.

There are trillions of strains of bacteria in the world, but only a few of these cause diseases in humans. Some of them live inside our gut.

There are many risk factors associated with the onset of bacterial infections
However, researchers do not know why people with the same health condition in the same family, some are prone to infectious disease, while others do not.

The most common symptoms of bacterial infection include redness and heat, swelling, fever, and pain at the site of infection.

In severe cases, the patient may also experience symptoms of swollen lymph glands.

Most cases of bacterial infection can be treated successfully if the types of bacteria that cause the infection are identified.

The onion is a plant in the genus Allium, belonging to the family Alliaceae, a closely related to garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures.


Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild or sweet.

In finding a potential compound for the treatment of infectious disease researchers examined the antibacterial and possible antibiotic potentiating activity of garlic and onion.

The study compared the efficacy of decoction as traditionally used and methanol, ethanol, ethyl acetate, and acetone extracts of onion and garlic on 15 bacterial strains (6 ATCC strains and 9 clinical isolates).

According to the tested differentiation,
* Ethyl acetate extract of onion combined with Streptomycin produced an indifferent effect on all tested bacterial strains.

* Ethyl acetate extract of onion combined with Chloramphenicol showed a synergistic effect against ATCC S. aureus (FIC 0.27-0.30) and Micrococci species (FIC 0.27-0.32).

The antibacterial activity of onion extracts may be attributed to the presence of a high concentration of phenolic compounds in the onion.

In other words, the antibacterial property of onion is totally dependent on the antioxidant content which may be altered due to the different methods of growth, including conventional and organic cultivation.

Based on the findings, researchers said, "This study has provided an opportunity to establish valuable baseline information on the antibiotic potentiating activity of onion and... which can be further exploited for the treatment and/or management of infectious diseases".

Taken together, onion may be considered a remedy for the prevention and treatment of infectious disease, pending the confirmation of the larger sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Onion and Garlic Extracts Potentiate the Efficacy of Conventional Antibiotics against Standard and Clinical Bacterial Isolates by Mahomoodally F1, Ramcharun S1, Zengin G. (PubMed)

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