Kyle J. Norton
Antiplatelet activity is an action that prevents and treats blood clots.
Platelets are tiny blood cells that protect the other to prevent injury and infection by forming clots to stop bleeding.
Platelets are made in the bone marrow which also produces white and red blood cells.
Diseases associated with low and abnormal blood platelets include
* Thrombocytopenia is a condition characterized by low blood platelets due to abnormal function of the bone marrow that makes platelets. patients with thrombocytopenia due to the low quantity of blood platelets may experience symptoms of a bruise, internal bleeding, and nosebleed.
Long-term untreated thrombocytopenia has been found to increase the risk of cancer, liver disease, pregnancy, infections, and an abnormal immune system.
* Essential thrombocythemia is a disease associated with overproducing blood platelets by the bone marrow, leading to symptoms of blood clots that form and block the blood supply to the brain or the heart.
* Secondary thrombocytosis is also another condition caused by too many platelets produced by the bone marrow.
Most cases of secondary thrombocytosis are associated with other medical conditions such as anemia. The most common symptoms of secondary thrombocytosis are infection, inflammation, some types of cancer, and reactions to medicines.
* Platelet dysfunction is a rare condition that links to poor platelet function. In other words, it is a disease caused by abnormal function of blood platelets without affecting the number of platelets in the blood.
This means the number of platelets is normal, but the platelets don't work as they should. Medicines such as aspirin can cause this. It's important to know which medicines affect platelets. Know that while taking these medicines you have an increased risk of bleeding.
Antiplatelet agents used in conventional medicine process the main function to prevent platelets from clumping. However, they also exert a similar effect as anticoagulation in the prevention of blood clots from forming and growing.
The onion is a plant in the genus Allium, belonging to the family Alliaceae, closely related to garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures.
Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild or sweet.
In finding a potential compound for the treatment of platelet aggression against the risk of cardiovascular disease, researchers examined the pharmacological aspect of onion antiplatelet activity in human subjects
The study included 12 human subjects who received yellow hybrid storage onions that were steamed for 0, 1, 3, 6, 10, and 15 min.
According to the tested assay, steamed onions not only destroyed the antiplatelet activity between 3 and 6 min of steaming but also stimulated platelet activity at 10 min of steaming without affecting the polyphenolic concentration and soluble solids.
Furthermore, cooked onion extracts also reverse the inhibitory effect on blood platelets by 25%, compared to steamed onion.
The findings were consistent across all donors.
The results strongly suggested that cooked onion preparations may result in the destruction or reversal of antiplatelet activity.
Moreover, in examining the anti-blood platelet activity of f2 different cooking systems of a convection oven and microwaves) in several time-temperature variables, researchers also found that
* Whole", "quarters", and "crushed" onions lost their antiplatelet activity after 30, 20, and 10 min of oven heating, respectively.
* Extensively cooked onions may stimulate platelet aggregation instead of antiplatelet aggregation.
Collectively, raw onion processed anti-antiplatelet activity compared to the cooked and extensive cooked onion in the promotion of platelet aggregation
Taken together, raw onion may be considered an antiplatelet remedy for the prevention and treatment of cardiovascular disease, pending the confirmation of the larger sample size and multicenter human study.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Steam-cooking rapidly destroys and reverses onion-induced antiplatelet activity by Hansen EA1, Folts JD, Goldman IL. (PubMed)
(2) Effect of processing and cooking conditions on onion (Allium cepa L.) induced antiplatelet activity and thiosulfinate content by Cavagnaro PF1, Galmarini CR. (PubMed)
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