Kyle J. Norton
Metabolic syndrome is a cluster of conditions that increase the risk of heart disease, stroke, and diabetes, including too much fat around the waist, high blood pressure, triglycerides, and blood sugar, and low HDL cholesterol.
People who have 3 or more aforementioned conditions are at a higher risk of heart disease, stroke, and diabetes. However, most people with metabolic syndrome have never developed cardiovascular disease (CVD) or diabetes.
Most common symptoms of metabolic symptoms are depending totally on the clustered conditions, including thirst and urination, fatigue, and blurred vision due to high blood glucose. However, in patients with no condition of hyperglycemia, metabolic syndrome is asymptomatic.
Epidemiologically, aging, ethnicity, obesity, medical condition such as diabetes, nonalcoholic fatty liver disease, and polycystic ovary syndrome are most risk factors found in patients with the syndrome.
Conventionally, the treatment of metabolic syndrome is totally depending on the cluster of condition. People with fat around the waist or obese are recommended to lose weight in a weight management program accompanied by diet change.
Some researchers suggested that the promotion of the Western diet in the US over the past few decades may have a strong effect in inducing the widespread metabolic syndrome.
Dr. Drake I, the lead scientist wrote, "The 'Western' dietary pattern was inversely associated with HDL-cholesterol and positively with all other response variables (both at baseline and follow-up), but there was no association with LDL at follow-up".
And, " In conclusion, this study supports current food-based dietary guidelines suggesting that a 'Western' dietary pattern with high intakes of sugar-sweetened beverages and red and processed meats and low intakes of wine, cheese, vegetables, and high-fiber foods is associated with detrimental effects on cardio-metabolic health".
The results clearly suggested if you are following a traditional diet with high fruits and vegetables and fewer in processed food, saturated and trans fat, and red meat accompanied with moderate exercise daily, your risk metabolic syndrome can be decreased substantially.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and for the treatment of flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
In finding a potential compound that processes an anti-metabolic syndrome activity, researchers examined the Black seeds and Turmeric alone and its co-administration in lower doses among patients with metabolic syndrome (MetS).
The double-blind-randomized-controlled trial included a total of 250 healthy males with MetS randomized to either Black seeds (1.5g/day), Turmeric (2.4g/day), its combination (900mg Black seeds and 1.5g Turmeric/day) or placebo for 8 weeks.
Based on the analysis, compared to the baseline, at 4 weeks, Black seed and Turmeric alone showed improvement in the parameters associated with the risk of MetS including the body-mass-index (BMI), waist circumference (WC), and body-fat-percent (BF%).
Furthermore, also at week 4, the combination improved all parameters involved in the risk of MetS, except HDL-cholesterol with lower fasting blood glucose (FBG) and LDL-cholesterol, compared to placebo.
Moreover, at 8 weeks, Black seeds reduced lipids and FBG, whereas turmeric reduced LDL-cholesterol and CRP, compared to placebo.
More importantly, the combination group with a 60% dose of the individual herbs showed an improvement in all parameters from baseline, compared to placebo.
In other words, the combination showed complete inhibition of all parameters associated with the onset of metabolic syndrome compared to the selected inhibition of individual herbal medicine. Black seeds + Turmeric showed much better efficacy than the use of Black seed and Turmeric alone.
Based on the results, researchers said, " The combination of Black seeds and Turmeric can, therefore, be recommended with lifestyle modification as a starting point for patients with MetS to halt its future complications and progression".
Taken altogether, turmeric processed abundantly bioactive compound curcumin may be used alone or combination with Black seed for the prevention and treatment of metabolic syndrome, pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Clinical efficacy of the co-administration of Turmeric and Black seeds (Kalongi) in metabolic syndrome - a double blind randomized controlled trial - TAK-MetS trial by Amin F1, Islam N2, Anila N3, Gilani AH. (PubMed)
(2) Coadministration of black seeds and turmeric shows enhanced efficacy in preventing metabolic syndrome in fructose-fed rats by Amin F1, Gilani AH, Mehmood MH, Siddiqui BS, Khatoon N. (PubMed)
(3) A Western dietary pattern is prospectively associated with cardio-metabolic traits and incidence of the metabolic syndrome by Drake I1, Sonestedt E1, Ericson U1, Wallström P2, Orho-Melander M. (PubMed)
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