Friday, 6 October 2023

#ManukaHoney Eye Drops (Optimel, Melcare, Australia) in the Treatment of #OcularDemodex and #DryEye, Reserachers Say

Kyle J. Norton

Scientists may have found a natural alternative for the treatment of Ocular Demodex and Dry-Eye, according to studies.

Believe it or not, the Demodex in eyelashes that cause the severity of ocular discomfort is quite common in the US. According to US Federal Science, over 70% of Americans suffer from the presence of Demodex without even noticing.

The increase in age, and patients with conjunctival papillary hypertrophy, are some most common Demodex risk factors.

Furthermore, methicillin-resistant Staphylococcus aureus (MRSA) was detected more often on eyelids with Demodex.


The finding strongly suggested that Demodex plays a pathogenic role in the ocular discomfort linked with aging.

Dry eye happens mostly in older adults is a condition in which a person doesn't have enough quality tears to clean and nourish the eye, leading to a chronic vision problem.

Dry eye, in most cases, is caused by the inadequate amount of tears due to lower than normal amount of tear production or tears evaporating too quickly from the eyes and poor quality of tears.

People with dry eyes may experience symptoms of irritation, gritty, scratchy or burning eyes; a feeling of something in their eyes; excess watering; and blurred vision.

Honey is a miraculous product made by bees using nectar from flowers.,

The rich golden liquid is considered one of the healthy sweet foods for replacing the use of white sugar and artificial sweeteners by many people.

Researchers with an aim to find a natural source for the treatment of vision problem compared the Manuka honey and tea tree oil against ocular Demodex.

The study included 53 viable Demodex mites acquired from the epilated eyelashes of 9 participants with blepharitis and symptomatic dry eye. Then, the viable mites were randomized to one of five treatment groups: cyclodextrin-complexed and uncomplexed Manuka Honey, 100% and 50% tea tree oil, and no treatment.

Compared to the results of four treatments, researchers found that the survival probabilities are lowest with 100% tea tree oil, and highest with cyclodextrin-complexed and uncomplexed Manuka Honey.

The finding clearly suggested that the efficacy of cyclodextrin-complexed Manuka honey was comparable with 50% tea tree oil, an established treatment for ocular Demodex.

In order to reveal more information about honey anti-dry eye effects, researchers evaluated
the effects of Manuka (Leptospermum sp.) honey eye drops (Optimel, Melcare, Australia).

The study included 24 participants aged 20 to 55 years with contact lens-related dry eye randomized to two treatment groups with 20 completing the study.


One group received Optimel eye drops twice a day for two weeks followed by conventional lubricant (Systane Ultra, Alcon) therapy for two weeks while the other group completed the treatments in the reverse order.

The Optimal treatment exerted an improvement in Dry eye symptoms significantly and patients with more severe symptoms at baseline showed a greater improvement in symptoms.

Seventy-five% of contact lens wearers reported good adherence to Optimel treatment and 95% reported no issues using this product.

However, due to the short duration of treatment, there were no significant differences observed in the objective signs of a dry eye.

Researchers at the experiment wrote in the final report, "Optimel Eye Drops reduce the symptoms of dry eye in contact lens wearers and are safe to use".

Taken together, honey, particularly Tualang honey may be considered a functional remedy for the prevention and treatment of ocular Demodex and dry eye, pending the confirmation of a larger sample size and multicenter human study.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.

Sources
(1) Comparing the in vitro effects of MGO™ Manuka honey and tea tree oil on ocularDemodex viability by Frame K1, Cheung IMY2, Wang MTM2, Turnbull PR1, Watters GA2, Craig JP. (PubMed)
(2) Treatment of contact lens related dry eye with antibacterial honey by Wong D1, Albietz JM1, Tran H1, Du Toit C1, Li AH1, Yun T1, Han J1, Schmid KL. (PubMed)

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