Sunday, 8 October 2023

#Greentea 's EGCG Inhibts Bacteria Associated with Poor #OralHealth, Researchers Say

Kyle J. Norton

Green tea is found to have a potential effect in the promotion of oral health against bacterial-induced tooth decay or cavities, a renowned institute suggested.
Green tea, a precious drink processes numbers of health benefits known to almost everyone in Asia and the Western world. However, as yin in nature herbal medicine or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including lack of energy, weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory.

According to the Technion-Israel Institute of Technology, Polyphenols including epigallocatechin 3 gallate (EGCG) isolated from green tea ameliorated oral cavity oxidative stress and inflammation, cigarette smoking and cigarettes' deleterious compounds nicotine and acrolein.


Dr. Narotzki B, the lead author of the study said, " Generally, green tea defends healthy cells from malignant transformation and locally has the ability to induce apoptosis in oral cancer cells. Altogether, there is an increasing interest in the health benefits of green tea in the field of oral health".


In the review of beneficial effects of green tea on oral disease, researchers found that green tea not only reduced the bacterial activity in the oral cavity in the expression of the aforementioned oral afflictions but also attenuated the risk of oral cancer through the antioxidant activities.

EGCG, in Solobacterium, moorei, a volatile sulfide compound (VSC)-producing Gram-positive anaerobic bacterium study, displayed a significant effect in inhibiting the growth of S. moorei, with MIC values of 500 and 250 μg/ml resulting in reduced the adherence of S. moorei to oral epithelial cells.


The study also suggested the efficacy of green tea extract and EGCG protected oral health by inhibited the progression of Solobacterium moorei probably through the ameliorated S. moorei's β-galactosidase activity in the production of volatile sulfide compound (VSC) in doses dependent manner.

Green tea with abundant natural compounds may be the next generation of whole food used a therapeutic supplement in promoted oral healthcare.


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Sources
(1) Green tea: a promising natural product in oral health by Narotzki B1, Reznick AZ, Aizenbud D, Levy Y.(PubMed)
(2) Green Tea (Camellia Sinensis): Chemistry and Oral Health by Khurshid Z1, Zafar MS2, Zohaib S3, Najeeb S4, Naseem M5.(PubMed)
(3) Green tea extract and its major constituent epigallocatechin-3-gallate inhibit growth and halitosis-related properties of Solobacterium moorei by Morin MP1, Bedran TB2, Fournier-Larente J3, Haas B4, Azelmat J5, Grenier D6.(PubMed)

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