#Ginger's 6 #Shogaol Inhibits Aging Processes, According to Scientists

Kyle J. Norton

Aging is a natural process of becoming older. Antiaging is a term that relates to delayed aging. In other words, anti-aging is an action that makes your appearance look younger than your biological age.
The cause of aging has many theories, including the theory of the accumulation of damage due to oxidative stress in the initiation of DNA oxidation and the programmed aging concept due to DNA methylation.


However, regardless of the theories, the decrease in hormone production gradually found in the human body may be one of the major causes of aging progression.

In fact, reduced production of hormones affects the amount of hormone released into the bloodstream, leading to decreased functioning of the target organs and systems.

Some researchers suggested that improved nutrient intake may have a strong effect in delaying the progression of aging and reducing the risk of age-related diseases.

Dr. Simpson SJ, the lead scientist in the joint study led by the University of Sydney wrote, "Nearly a century of research has shown that nutritional interventions can delay aging and age-related diseases in many animal models and possibly humans".


And, "Nutritional geometry provides new perspectives on the relationship between nutrition and aging by focusing on calories, macronutrients and their interactions across a landscape of diets, and taking into account compensatory feeding in ad libitum-fed experiments".


The results strongly suggested that if you follow a healthy diet with nutrients diet by focusing on calories, and macronutrients, you may delay the process of biological aging.


Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.

The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.

Researchers on finding a natural ingredient that processes anti-aging properties examined the ameliorative effects of two antioxidant supplements, ginger and alpha lipoic acid (ALA), on hepatic ultrastructural alterations in old rats by evaluating the livers of young (4 months) and old (24 months) Wistar rats.

Before administration of ginger and ALA, the livers of old rats showed sinusoidal collapse and congestion, endothelial thickening and defenestration, inconsistent perisinusoidal extracellular matrix deposition, and aged hepatocytes associated with reduced liver function.

Injection of ginger and ALA supplementation completely normalized all the alternation due to aging in the tested old rats.

The findings strongly suggested the use of ginger and ALA as anti-aging products for improvement based on their amelioration of ultrastructural alterations in the livers of old rats.

Additionally, in order to get more information about ginger's antiaging effects, researchers examined the anti-aging natural products, the active constituent 6-shogaol isolated from ginger.

Application of the tested compound showed the lifespan-extending effect in a dose-dependent manner in Caenorhabditis elegans.


The anti-aging activity effects were attributed to 6 gingerols in increasing oxidative stress tolerances via antioxidant enzyme induction.

In the depth differentiation, researchers surprisingly found that 6-shogaol inhibits the aging process independent from other aging-related factors of C. elegans.

Taken together, ginger processed with high levels of 6 gingerols may be considered a functional anti-aging remedy, pending the confirmation of a larger sample-sized and multicenter human study



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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Lifespan-extending property of 6-shogaol from Zingiber officinale Roscoe in Caenorhabditis elegans by Lee EB1,2, Kim JH1, Kim YJ1, Noh YJ1, Kim SJ1, Hwang IH1, Kim DK3. (PubMed)
(2) Ginger and alpha lipoic acid ameliorate age-related ultrastructural changes in rat liver by Mahmoud YI1, Hegazy HG1. (PubMed)
(3) Dietary protein, aging and nutritional geometry by Simpson SJ1, Le Couteur DG2, Raubenheimer D3, Solon-Biet SM4, Cooney GJ4, Cogger VC2, Fontana L. (PubMed)