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Tuesday, 11 October 2016

Antioxidants: Neurodegenrative diseases - Alzheimer's disease: The Risk Factors

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Human aging is a biological process, no one can stop, but delay it. It is possible that one person has a physiological younger than his or her biological if one engages in healthy living life style and eating healthily by increasing the intake of good healthy food such as whole grain, fruits, vegetables, beans and legumes, etc. and reducing the consumption of harmful foods, such as saturated fat, trans fat, artificial ingredients, etc.

                      

                 Neurodegenrative diseases

Neurodegeneration is defined as a health conditions of the progressive loss of structure or function of neurons, including death of neurons, includingParkinson’s, Alzheimer’s, and Huntington’s diseases due to genetic mutations, most of which are located in completely unrelated genes.


                                         Alzheimer's disease


Alzheimer's disease is defined as a health condition of an irreversible, progressive brain disease that slowly destroys memory and thinking skills, and eventually even the ability to carry out the simplest activity, due to the loss of neurons and synapses in the cerebral cortex and certain subcortical regions.


                         The Risk Factors


a. Age
Age is the most important risk factor. As we age, beside our body's ability to repair itself becomes less efficient, but also the accumulation of plague over the years has started affecting the functions of the brain due to cell death. The brain has reached the stage for the disease to occur. Over 1 in 20 Canadians over age 65 is affected by Alzheimer's disease.

b. Family history and Genetics
Although it happens to (5-7%) of the patience, but family history of certain genes mutation has caused the development of abnormal characteristics which associated with early onset Alzheimer's disease or Alzheimer's disease.

c. ApoE4 Gene
This gene is the most important genetic risk factor for the sporadic form of Alzheimer's disease. Since the ApoE genes regulate the production of a protein that helps carry cholesterol, but the inherited ApoE4 gene is associated with the high risk of the development of Alzheimer's disease.

d. Female Gender
Twice as many women get Alzheimer's disease than men, it may be due to female live longer than male. Other suggested that it is due to decline of production of estrogen and hormone replacement therapy.

e. Cardiovascular Disease
High blood pressure and cholesterol levels can contributed to plague building up in the brain cells. Strokes and mini-strokes can increase the risk of oxidation of the brain cells.

f. Oxidative stress
Oxidative stress is a significant cause in the formation of the disease.

g. Down Syndrome
People with trisomy 21 (Down Syndrome) have an extra gene copy which exhibits Alzheimer's disease by 40 years of age.

h. Etc.

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