Healthy Food Eggplants, the Cardio-Protective Veggies, Scientists Find

By Kyle J. Norton

Scientists may have found a whole fruit or vegetable with the potential to treat cardiovascular disease with no side effects, some studies found.

Cardiovascular disease is a class of conditions associated with heart and blood vessels. Anything that affects the normal heart and blood vessel functioning is considered risk factors of the disease, including heart muscle, valves, or rhythm, and blockage of blood vessels.

According to the statistics, in the US, approximately, 610,000 people die of heart disease every year that's 1 in every 4 deaths. The disease is the leading cause of death for both men and women.

The causes of cardiovascular diseases are associated with the location that affects the functioning of the heart and blood vessels, including atherosclerosis is caused by the blockade of the blood vessel due to the accumulation of plaques in the arteries and arrhythmias caused by abnormal heart rhythms.

Epidemiological studies strongly suggested that the most common cardiovascular disease that affects mostly heart disease patients is coronary artery disease (CAD).

Coronary artery disease (CAD) is the most common form of heart disease caused by one or more of the coronary arteries becoming narrow or blocked.

Some researchers suggested that the widespread diagnosis of coronary artery disease (CAD) in the Western world probably is a result of the promotion of the Western diet over the last few decades.


A diet high in bad cholesterol salts sugar and carcinogens associated with the accumulation of plaques on the arteries has been found to be a culprit of the onset of coronary artery disease in many studies.


Dr. Oikonomou E, the lead author in the joint study led by the National and Kapodistrian University of Athens in the concerns of CAD widespread in the Western world launched an investigation to examine the independent predictive value of an unhealthy diet on the severity of coronary artery disease (CAD).

In the total of 188 symptomatic stable patients with CAD. Patients were categorized as having severe CAD or nonsevere CAD by coronary angiography.

Among several demographics and clinical characteristics, all patients were tested using a semiquantitative food frequency questionnaire.

By analyzing the 8 principal components in the 8 distinct dietary patterns found in the returned questionnaire, researchers found that The Western dietary pattern (increased intake of fat, red meat, and carbohydrates and minimal consumption of fruits and green leafy vegetables) was predictive of severe CAD (area under the curve: 0.73, 95% confidence intervals: 0.64-0.83, P < .001).


These results not only suggested that the Western not only causes the onset of the disease but also increased the risk of severity of coronary artery lesions in patients with stable CAD.

The doctors in the study wrote the final report, "the findings highlight the role of dietary patterns when estimating cardiovascular risk for the management of patients with CAD".

Eggplant is a species of S. melongena, belonging to the family Solanaceae and native to India.

The plant has been cultivated in southern and eastern Asia since prehistory. It is famous for its deep purple and the best eggplant can be found from August through October when it is in season.

The chemical constituents of eggplant include sterols (i.e. typical plant sterols, androstane, pregnane, and cholestane derivatives, steroidal alkaloids, and sapogenins), phytosterols, triterpenes, δ-amyrin, Chlorogenic acid, Nasunin, and other Polyphenolic compounds.

In the finding, a natural compound with the efficacy for the prevention and treatment of cardiovascular disease with no side effects, researchers at the University of Connecticut School of Medicine examine the role of raw and grilled eggplants on cardioprotection using an isolated perfusion heart model.


The animals were fed freeze-dried products of either raw or grilled eggplants for 30 days. After 30 days, isolated working hearts were subjected to 30 min ischemia followed by 2 h of reperfusion.

The medical assays suggested eggplants process potent cardioprotective compounds judging by their ability to increase left ventricular function, and reduce myocardial infarct size and cardiomyocyte apoptosis.

Interestingly, researchers found no difference in cardioprotective ability between the raw and grilled products.

Based on the antioxidant vitamins classification, researchers showed that vitamin A, vitamin C, and β-carotene, were lower and some of the polyphenolic components, especially nasunin content, were higher in grilled eggplants, These results indicated that there must be some other ingredient processed by both grill and raw eggplants that exert cardiovascular diseases not found in this study.


Moreover, in the study to analyze total phenolics and antioxidant capacity in the indigenous vegetables for cardioprotective effect researchers at the Tuskegee University conducted a group analysis including collard greens, mustard greens, kale, okra, green onion, butter beans, butter peas, purple hull peas, rutabagas, and eggplant.

At a concentration of 10.0 mg dried vegetable equivalent/ml, the extract of these vegetables exerted a significant antioxidant activity by reducing 13.2-88.5% DPPH(•) radical in 30 min.

The Oxygen Radical Absorbance Capacity. (ORAC) value ranged from 2.5 to 100.7 µmoles of Trolox equivalents per gram of dried sample.

The antioxidant capacity of the vegetable samples was highly related to their total phenolic content.

The evidence suggested these indigenous vegetables are good sources of phenolic compounds, which might provide anti-oxidative protection against free radicals in inducing chronic diseases, such as cardiovascular disease.

Taken altogether, eggplant processed abundantly bioactive antioxidants may be considered a functional vegetable for the prevention and an adjunct therapy combined with the primary medicine for the treatment of cardiovascular disease without inducing any adverse effects

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Cardioprotective properties of raw and cooked eggplant (Solanum melongena L) by Das S1, Raychaudhuri U, Falchi M, Bertelli A, Braga PC, Das DK. (PubMed)
(2) Total phenolics and antioxidant capacity of indigenous vegetables in the southeast United States: Alabama Collaboration for CardiovascularEquality Project by Huang Z1, Wang B, Eaves DH, Shikany JM, Pace RD. (PubMed)
(3) Western Dietary Pattern Is Associated With Severe Coronary Artery Disease by Oikonomou E1, Psaltopoulou T2, Georgiopoulos G1, Siasos G1,3, Kokkou E1, Antonopoulos A1, Vogiatzi G1, Tsalamandris S1, Gennimata V1, Papanikolaou A1, Tousoulis D. (PubMed)

Healthy Food Ginger May Process Anti Obesity Property, Researchers Say

By Kyle J Norton 

Ginger may be considered a functional food for the prevention and treatment of obesity without inducing side effects, some scientists found.

Obesity is a medical disease associated with extreme overweight.

In other words, obesity is the accumulation of excess fat to the extent that it may have an adverse effect on patient health.

According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered overweight, and a BMI of over 30 is an indication of obesity.

According to the statistic, 68% of the American population is either overweight or obese.

What causes obesity? Some researchers suggested that too much calories consumption and lack of physical exercise are the 2 main causes of obesity in once healthy individuals.

Some scientists indicated, there is no coincidence but a close correlation between the onset of obesity in a large percentage of Americans and the promotion of the Western diet in the past few decades.

Dr. Bortolin RC, the lead researcher in the obese team in the joint study led by the Instituto de Ciências Básicas da Saúde-Universidade Federal do Rio Grande do Sul (UFRGS in the examine the new animal diet based on human Western diet said, "Obesity is a metabolic disorder that predisposes patients to numerous diseases and has become a major global public health concern".


And, " diet, and not the obese state, was the major driving force behind gut microbiota changes. Moreover, the marked dysbiosis observed in CAF-fed rats might have resulted from the presence of several additives present in the CAF diet, or even a lack of essential vitamins and minerals".

These results strongly suggested that the Western diet alters the gut microbiota composition (dysbiosis) probably due to substances found in the Western diet foods, that are not found in other diets, compared to the group treated with HFD developed the greatest dysbiosis independent of obesity

Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.

The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.

On finding natural ingredients or whole food for the treatment of obesity researchers examine the traditional use of ginger in an animal model.

Application of ginger in vivo and vitro demonstrated a potential anti-obesity effect in regulating the PPARγ signaling pathway in adipocytes in the initiation of obesity,

Diet-induced obesity was attenuated in C57BL/6J mice treated with the dietary ginger extract (GE)also exhibited an increase in energy expenditure.



GE also exerted an anti-obesity effect through promoting the increased number of Types I muscle fibers, running endurance capacity, and upregulated PPARδ-targeted gene expression in skeletal muscle

Furthermore, the cellular respiration assay also revealed that pretreating cultured skeletal muscle myotubes with GE increased palmitate-induced oxygen consumption rate, which suggested an increase in cellular fatty acid catabolism, another anti-obesity activity.

After taking into account co and confounders, researchers said, "6-Shogaol and 6-gingerol (the ginger bioactive constituents)may be responsible for the regulatory effects of dietary ginger on PPARδ signaling".

Moreover, additional investigation of ginger exerts protective on obesity and its complications, researchers showed that gingerenone A, a bioactive compound isolated from ginger had the most potent inhibitory effect on adipogenesis and lipid accumulation in 3T3-L1 cells among ginger components at a single concentration (40 μM).

In vitro data, GA attenuates diet-induced obesity (DIO) by reducing fat mass in mice, accompanied by a modulation of fatty acid metabolism via activation of AMP-activated protein kinase (AMPK) in stimulating weight loss, in vitro and in vivo.

Dr.Suk S the lead author said in the final report, " GA may be used as a potential therapeutic candidate for the treatment of obesity and its complications by suppressing adipose expansion and inflammation".

Taken altogether, ginger processed abundant bioactive compounds may be considered a functional food in stimulating weight loss in obese subjects.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.





Sources
(1) Beneficial effects of ginger Zingiber officinale Roscoe on obesity and metabolic syndrome: a review by Wang J1,2, Ke W1, Bao R1, Hu X1,2, Chen F. (PubMed)
(2) Ginger extract prevents high-fat diet-induced obesity in mice via activation of the peroxisome proliferator-activated receptor δ pathway by Misawa K1, Hashizume K2, Yamamoto M3, Minegishi Y4, Hase T5, Shimotoyodome A. (PubMed)
(3) Gingerenone A, a polyphenol present in ginger, suppresses obesity and adipose tissue inflammation in high-fat diet-fed mice by Suk S1, Kwon GT2, Lee E1, Jang WJ1, Yang H1, Kim JH3, Thimmegowda NR4, Chung MY1, Kwon JY5, Yang S1, Kim JK1,5, Park JHY2,3, Lee KW. (PubMed)
(4) A new animal diet based on human Western diet is a robust diet-induced obesity model: comparison to high-fat and cafeteria diets in term of metabolic and gut microbiota disruption by Bortolin RC1, Vargas AR1, Gasparotto J1, Chaves PR1, Schnorr CE1, Martinello KB2, Silveira AK1, Rabelo TK3, Gelain DP1, Moreira JCF. (PubMed)

Herbal Ashwagandha, the Best Antioxidant Functional Remedy

By Kyle J. Norton

Oxidative stress is a condition of imbalance of the ratio of antioxidants and free radicals in the body. In other words, the overproduction of free radicals accompanied by the decreased levels of antioxidants may cause cytotoxicity in the induction of oxidative stress.

Some researchers suggested long-term suppression by oxidative stress can activate the expression of over 500 different genes, including those for growth factors, inflammatory cytokines, chemokines, cell cycle regulatory molecules,...

Oxidative stress-activated inflammatory pathways have been found to induce the transformation of cell DNA to cause cancer and, chronic diseases.

Free radicals are highly reactive molecules with an unpaired electron on the outer ring of the atom.
Due to its nature to become stable, free radicals readily to donate or steal an electron from other molecules, leading to the chain of domino's effect that can not be stopped until either the electrons are paired or inhibited by antioxidants.

This chain of reaction is the cause of oxidative stress, a condition is associated with either overexpression of free radicals or depletion of antioxidant enzymes produced by the host organs.

Antioxidants are stable atom that plays a critical role in protecting the body against the attack of free radicals.

In other words, antioxidants inhibited the onset of free radicals before they can cause a chain reaction in facilitating the protein, lipid, and cell DNA damage.

Antioxidants can either be produced by the liver or intake from dietary sources. Under normal conditions, antioxidant enzymes produced by the body in a healthy individual are good enough to counter the bombardment of free radical attacks.

However, in people with a weakened immune system, intake of dietary sources of antioxidants may be necessary.

Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, the Middle East, and the Mediterranean.

The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine for over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.

On finding a potent compound that processes the antioxidant activity, researchers investigated the effects of Withania somnifera on copper-induced lipid peroxidation and antioxidant enzymes in the aging spinal cord of Wistar rats.

According to the tested differentiation, the application of Withania somnifera exerted a strong effect on the levels glutathione peroxidase (GPx) which were decreased significantly in the spinal cord from adult to aged mice.

Withania somnifera also successfully inhibited lipid peroxidation in a dose-dependent manner through its antioxidant activity.

Furthermore, these effects were found to be similar to those of superoxide dismutase and mannitol.

Based on the findings, researchers said, "The results indicate the therapeutic potential of Withania somnifera in aging and copper-induced pathophysiological conditions".

Taken altogether, Ashwagandha may be considered a functional herb for the prevention of diseases associated with oxidative stress, pending the result of a larger sample size and multicenter study

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You  How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Withania somnifera (Ashwagandha) attenuates antioxidant defense in aged spinal cord and inhibits copper induced lipid peroxidation and protein oxidativemodifications by Gupta SK1, Dua A, Vohra BP. (PubMed)

Navy Bean, the Anti-Hypertension Health Food

By Kyle J. Norton

High blood pressure or hypertension is a medical condition characterized by abnormally high blood pressure in the arteries. High blood pressure is also a condition in the cluster of metabolic syndrome that increases the risk of heart disease, stroke, and diabetes.

Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood.

Although at the early stage, high blood pressure usually does not cause symptoms, some patients in extreme cases may experience dizziness and light head, shortness of breath, nosebleeds, flushing, chest pain, and visual changes.

Underlying medical conditions such as kidney disease and long-term stress are associated with high blood pressure.

More precisely, according to the American hypertension Association, long-term untreated high blood pressure can induce complications such as
* Heart attack is caused by damaged arteries due to high blood pressure that leads to blockage or limited blood flow to the heart muscle.

* Stroke, damaged blood vessels in the brain may be clogged and burst.


* Heart failure, high blood pressure increases the risk of enlarged-heart that limits the heart function in blood circulation


Conventional hypertensive medications have undoubtedly prevented many deaths from heart disease in the past 30 years, but they have many side effects.

If you currently taking hypertensive medicine, please make sure you know all the side effects of the preventive measure.

Some researchers also found that excessive energy intake and obesity are major causes of hypertension.

Dr. Savica V, the lead author in the study "The effect of nutrition on blood pressure" wrote, "Obesity is associated with increased activity of the renin-angiotensin-aldosterone and sympathetic nervous systems, possibly other mineralocorticoid activity, insulin resistance, salt-sensitive hypertension, and excess salt intake, and reduced kidney function".

High sodium chloride intake strongly predisposes to hypertension".

"Increased alcohol consumption may acutely elevate blood pressure. High intakes of potassium, polyunsaturated fatty acids, and protein, along with exercise and possibly vitamin D, may reduce blood pressure".


The small, white navy bean, also called pea bean or haricot, popular in both dry and green forms, is very popular in Britain and the US, native to Peru. It is now grown and consumed across the world, due to its numerous health benefits.

With an aim to find a potential ingredient for the treatment of hypertension, researchers investigated the inhibitory activities of the navy bean by preparation of navy bean milk (NBM) subjected to fermentation of four lactic acid bacteria (LAB) strains, namely, Lactobacillus helveticus MB2-1, Lactobacillus plantarum B1-6, and Lactobacillus plantarum 70810.

According to the tested assays, all fermented NBM showed higher angiotensin I-converting enzyme (ACE) inhibitory activity compared to the unfermented ones.



By comparison of each strain, researchers found that 2 h, 3 h, and 5 h are the optimum fermentation periods for respectively L. plantarum 70810, L. plantarum B1-6 and L. bulgaricus.

Compared to the IC value without causing an intestinal disturbance, the extracts fermented by L. plantarum B1-6 exerted the lowest IC50 value of 21 ± 2.1 μg protein ml(-1).


Angiotensin-converting enzyme (ACE) is a central component of the renin-angiotensin system (RAS), which controls blood pressure by regulating the volume of fluids in the body.

In other words, the effect of LAB fermentation on the degradation of navy lean proteins and the capacity to release ACE inhibitory peptides may have a strong effect on the inhibition of hypertension.


Dr. Rui X, after taking other factors into account wrote, "The approach was promising to obtain probiotic products with the potential to serve as functional ingredients targeting hypertension".

Taken altogether, the fermented navy bean may be considered a remedy for the prevention and treatment of hypertension, pending the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Enrichment of ACE inhibitory peptides in navy bean (Phaseolus vulgaris) using lactic acid bacteria by Rui X1, Wen D, Li W, Chen X, Jiang M, Dong M. (PubMed)
(2) The effect of nutrition on blood pressure by Savica V1, Bellinghieri G, Kopple JD(PubMed)

Omega-3 Fatty Acid Inhibits the Depressive Symptoms Regardless of Serum of Oxidated-LDL/LDL

By Kyle J. Norton

Depression is a normal response as part of our daily lives such as the loss of s job, the death of a loved one, and illness.

Over 30 million Americans suffer from depression and the amount is increasing at an alarming rate. Depression may be a mental health disorder that can affect the way you eat, sleep, and the way you feel about yourself. 

The mild case of depression can be defeated by a variety of self-care techniques. Others require the treatment of medication, such as antidepressant medications and psychotherapy that help to reduce and sometimes eliminate the symptoms of depression.

The most common depressive symptoms are feelings of helplessness and hopelessness, loss of interest in daily activities, appetite or weight changes, sleep changes, anger or irritability, reckless behavior and loss of concentration.

Cholesterol is a waxy substance that is produced either by the liver or injected from animal food sources.

Cholesterol found in our body is needed for our body to build cell walls, hormones, and vitamin D, and create bile salts that aid digestion. However, too much of them, in most cases due to the intake of animal protein can cause plaques built up on the arterial wall, the major cause of heart disease and stroke.

More precisely, if levels of low-density lipoprotein are high compared to high-density lipoprotein which returns the accessed cholesterol back to the liver, you have high blood cholesterol.

In other words, healthy blood cholesterol is any level with either less than or equal to 4 (low-density lipoprotein/ 1 (high-density lipoprotein).

According to the statistics, in 2015-2016, by age and gender, a total of 12.4 percent of adults aged 20 years and over had high cholesterol in the United States.

Lipoproteins are a general term of fat, cholesterol, and apolipoproteins, including the 2 most common forms of LDL (Low-Density Lipoprotein) and HDL (High-Density Lipoprotein).

Low-Density Lipoprotein is also known as bad cholesterol in the form of lipoprotein in which cholesterol is transported in the blood. High levels of low-density lipoprotein in the blood are associated with an increased risk of heart disease.

Lipoprotein ratio is the calculation of total/high-density lipoprotein (HDL) cholesterol and LDL/HDL cholesterol ratios which are considered indicators with greater predictive value than isolated parameters used independently in the prediction of the risk of heart disease.

Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.

The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

On finding a potential phytochemical for the treatment of high blood cholesterol, researchers examined the effect of Omega 3 fatty acid on low-density lipoprotein on patients LDL with depression

The study included a total of 133 female workers in a hospital and nursing homes recruited in Japan.
According to the tested analysis, serum oxidated-LDL/LDL was positively connected with depressive symptoms but was more strongly related to perceived psychological stress.

Patients showed an increased serum of pro-inflammatory cytokine (IL-6)  partly transmitted via ox-LDL/LDL with a positive correlation with depressive symptoms.

Serum ω3 PUFAsfound in the blood were inversely associated with depressive symptoms independently of IL-6 or ox-LDL/LDL.

Taken altogether, Omega-3 fatty acids may be considered a functional food for the treatment of depressive symptoms regardless of the levels of the IL-6 or ox-LDL/LD, pending the confirmation of the larger sample size and multicenter human study.

Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Serum IL-6 levels and oxidation rate of LDL cholesterol was related to depressive symptoms independent of omega-3 fatty acids among female hospital and nursing home workers in Japan by Tsuboi H1, Sakakibara H2, Tatsumi A3, Yamakawa-Kobayashi K4, Matsunaga M5, Kaneko H6, Shimoi K7. (PubMed)

Phytochemical Tocopherols Kill Glioma Cancer Cells in Vitro

By Kyle J. Norton


A glioma is a type of tumor that starts in the glial cells of the brain or the spine, comprising 30 percent of all brain tumors and central nervous system tumors.

Heterogeneous tumor cells of glioma are the type of cancer associated with genetic alterations that occur in individual tumors originating in the same organ.

Primary glioblastoma is considered the most aggressive cancer. Cancer may arise de novo, meaning they begin as a Grade IV malignant glioma tumor with no evidence.

Due to the rapid growth of the tumor, patients diagnosed with primary glioblastoma experience brain swelling and increased brain pressure, leading to symptoms of nausea, vomiting, and severe headaches and localized symptoms depending on the location of the tumor.

Radiation and chemotherapy are the most common forms of treatment for patients with glioblastoma particularly, in a tumor that cannot be removed with surgery.

According to the statistic, the median survival time of primary glioblastoma is approximately 3 months without medical treatment. Glioblastomas represent about 15% of all primary brain tumors.

Believe it or not, gliomas have been found accounting for 30 percent of all brain tumors and central nervous system tumors, and 80 percent of all malignant brain tumors.

Glioma can be classified into 3 types, including
* Astrocytomas are found in glial cells, star-shaped brain cells in the cerebrum called astrocytes. Most astrocytomas are localized.

* Ependymomas are cancers that grow in your brain or any part of the spine, including your neck and upper and lower back starting from the ependymal cells in the middle of your spinal cord and fluid-filled spaces in your brain.

* Oligodendrogliomas are cancers that begin on the oligodendrocytes of the brain or from a glial precursor cell.

The exact cause is unknown. Epidemiologically, age, exposure to radiation and family history are common risk factors that cause the onset of the disease,

Tocopherols are phytochemicals of which many have vitamin E activity, belonging to the group of Lipids, found abundantly in butter, egg yolk, milk fat, some vegetable, and seed or nut oils, etc.

On finding a most effective approach to glioma treatment, researchers examined the effects of a pH-sensitive core-shell nanoparticle (PDCP-NP) that targets the cancer stem cells (CSCs) and the differentiated tumor cells.

Where PDCP-NP is a cationic micellar core (Cur-M) that was first prepared from d-α-tocopherol-grafted-ε-polylysine polymer to encapsulate the hydrophobic curcumin, followed by dopamine-modified-poly-γ-glutamic acid polymer further deposited on its surface as an anion shell through pH-sensitive linkage to encapsulate the hydrophilic doxorubicin (DOX) hydrochloride with the control of the combinational Cur/DOX molar ratio at 3:1.

According to the analysis, PDCP-NP showed a ratiometric delivery capability to target cancer stem cells (CSCs) and the differentiated tumor cells in vitro and Vivo, compared to those of the cocktail Cur/DOX solution.

Treatment with PDCP-NP displayed a significantly decreased percentage of CSCs in tumors from 4.16% to 0.95%.

Based on the results, researchers said, " PDCP-NP may be a promising carrier for the combination therapy with drug candidates having dissimilar physicochemical properties".

Taken altogether, tocopherols used in a combination with other phytochemicals and chemo drugs may be considered an adjunct therapy for the treatment of glioma, pending to the confirmation of the larger sample size and multicenter human study.

Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Ratiometric delivery of two therapeutic candidates with inherently dissimilar physicochemical property through pH-sensitive core-shell nanoparticles targeting the heterogeneous tumor cells of glioma by Xu HL1, Fan ZL1, ZhuGe DL1, Tong MQ1, Shen BX1, Lin MT1, Zhu QY1, Jin BH1, Sohawon Y2,3, Yao Q1, Zhao YZ. (PubMed)

Beta-Sitosterol Exerts a Neuro-Protective Effect in Vitro

By Kyle J. Norton

Cancer is a class of chronic diseases associated with irregular cell growth in the tissues of the affected organ.

Brain and spinal cord make up the nervous system. Brain and Spinal Cord tumors originated are not very common.

The function of the brain process a complex function, including control of our thoughts, memory, and speech, movement of the arms and legs,...

Brain cancer is a medical and chronic condition characterized by cell growth disorderly in the brain tissue.

Benign tumors are noncancerous, and malignant tumors are cancerous. More than 190.000 people in the US are diagnosed with a brain tumor each year alone.

A neuron is a nerve cell that forms a building block of the nervous system.

Neuroblastoma is cancer developed by the immature nerve cells found in several areas of the body, mostly in and around the adrenal glands.

Cancer most commonly affects children age 5 or younger compared to less often in older children.

According to the statistics provided by the Cancer Net, approximately 800 children are diagnosed with neuroblastoma in the United States.

And 90% of children affected by neuroblastoma are children younger than 5.

Sadly, the the-5-year survival rate of cancer is less than 50%.

The most common symptoms are totally depending on the area that has been affected including back pain, fever, unexplained weight loss, and bone pain.

Beta-Sitosterol is a phytochemical in the class of Phytosterols, belongings to the group of Lipids, found abundantly in avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, buckwheat. etc.

On finding a potential phytochemical for the prevention and treatment of brain cancer, researchers evaluated the neuroprotective effects and action mechanism of Cirsium setidens (CSEA) and Aster scaber (ASEA) against H2O2-induced cell death of human brain neuroblastoma SK-N-SH cells.

According to the experimental and chemical analysis, 

*The major phytochemicals isolated from CSEA and ASEA were found to be β-sitosterol, Dau, Pec, Ast, or isoquercitrin.

* Ethyl acetate fractions from Cirsium setidens (CSEA) and Aster scaber (ASEA) showed neuroprotective effects in SK-N-SH cells.

* Compared to β-sitosterol, pretreatment with Dau, Pec, or Ast showed protective effects against H2O2-induced cell death and inhibited ROS generation by oxidative stress to induce brain cell apoptosis.

In other words, all chemical compounds found in Cirsium setidens (CSEA) and Aster scaber (ASEA) work synergistically by inducing overexpression of free radicals to exert cytotoxicity against the tested cells.

Taken altogether, beta-Sitosterol used in a combination with other chemical compounds may be considered a supplement for the prevention and treatment of brain cancer, pending to the confirmation of the larger sample size and multicenter human study.

Intake of beta-Sitosterol in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Neuroprotective effects of phytosterols and flavonoids from Cirsium setidens and Aster scaber in human brain neuroblastoma SK-N-SH cells by Chung MJ1, Lee S2, Park YI3, Lee J3, Kwon KH. (PubMed)

Healthy Food Coffee and Coffee's Caffeine in Reducing The Risk of Colon Cancer, Studies Reveal

By Kyle J. Norton

Good news for coffee drinkers, coffee consumption regularly is associated with reduced risk of colon cancer, a renowned institute study suggested.

Coffee, becoming a popular and social beverage all over the world, particularly in the West, is a drink made from roasted beans from the Coffea plant, native to tropical Africa and Madagascar.

Colon Cancer is a disease characterized by irregular cell growth in the colon, with the tendency in spreading to distant parts of the body, depending on the stage.

According to the Federico II University of Naples, the efficacy of coffee consumption in attenuated risk of the colon may be attributed to its bioactive components, such as polyphenols, melanoidins, carbohydrates, diterpenes,...

Dr. Vitaglione P, the lead author said, " ...metabolism and composition, both coffee chlorogenic acids and dietary fiber, including melanoidins, may reduce CRC risk, increasing colon motility and antioxidant status".

However, phytochemicals found in coffee may be different that depends on the amount and type of compounds ingested with the beverage, the variety of coffee used, the roasting degree, the type of brewing method as well as the serving size.


Additionally, in the investigated the protective action of coffee against Caco-2 human colon carcinoma cells. researchers filed the following results
1. Even with low concentrations, coffee (<5%) inhibited the proliferation of Caco-2 cells without affecting normal cell viability.
2. . Increasing the duration of coffee bean roasting showed a significant in reduction the mutative risk of gene KRAS expression.

3 Coffee reduces the risk of colon cancer through suppressed miR-30c and miR-96, in promoted cell proliferation, migration and invasion, and enhanced tumor growth.

Interestingly, in the examine of the association between coffee consumption and CRC risk as well as a risk by anatomic subsite among Japanese, using data from the Hospital-based Epidemiological Research Program at Aichi CancerCenter I and II (HERPACC-I and II) with subjects enrolled in HERPACC-I between 1988 and 2000 and in HERPACC-II between 2001 and 2005, scientists found that returned self-administered questionnaire from participants, coffee consumption in reduced risk of colon cancer is associated to numbers of cup intake daily, in compared to non-drinker.

The relative odd ratio of less than 1 cup/day, 1-2 cups/day, and 3 or more cups/day for CRC were 0.88, 0.90, and 0.78 respectively.

Dr. Senda Nakagawa H, the lead author said, " Subsite-specific analysis revealed a significant inverse linear trend between coffee consumption and distal colon cancer (p-trend = 0.048), and a tendency toward a lower risk of rectal cancer (p-trend = 0.068)".

The finding evidence suggested that coffee and coffee caffeine may have a profound effect in reduced risk of cancer linearly.


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Author biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Coffee, colon function and colorectal cancer by Vitaglione P1, Fogliano V, Pellegrini N.(PubMed)
(2) Coffee reduces KRAS expression in Caco-2 human colon carcinoma cells via regulation of miRNAs by Nakayama T1, Funakoshi-Tago M1, Tamura H1.(PubMed)

Aloe Vera, the Anti-Microbial Herbal Medicine

By Kyle J. Norton

A recent study performed by a renowned institute suggested that intake of Aloe Vera or Aloe Vera supplement may reduce the risk of microbial infection and infectious diseases.

Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan, used in herbal medicine in treating many kinds of disease, including wound, burn- healing, minor skin infections, sebaceous cysts, diabetes, and elevated of cholesterols, etc.

In a total of Sixty students in the age group 6-12 years selected from an orphanage center, divided into four groups study, oral administration of Aloe Vera group showed a decrease of the bacterial count by 80.94% .

Dr. Bhati N, the lead author said, "Herbal dentifrices containing A. Vera... can be safely recommended as an alternative to fluoridated dentifrices in terms of antimicrobial efficacy".

In Streptococcus mutant strains, Aloe vera brushing showed a reduced bacteria contamination of Streptococcus mutant strains, without differentiation from the other chemical agents used.

In fact, Aloe vera in the study against pathogenic such as Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus cereus, Salmonella Typhimurium, Proteus vulgaris, Klebsiella pneumonia, Escherichia coli, Streptococcus pyogenes and Candida albicans displayed a significantly antimicrobial inhibition rate zones ranging from 6.0 ± 0.57 to 16.6 ± 0.57 mm as the result of the expression of bioactive compounds with high 2,2-diphenyl-1-picrylhydrazyl (DPPH, stable free-radical molecules isolated from the herb), composed of scavenging properties.

Taking together, oral administration of Aloe Vera is found to associate to reduced risk of microbial infection and infectious diseases, but a large amount intake should only be prescribed by related field specialists.


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1) Evaluation of antimicrobial efficacy of Aloe vera and Meswak containing dentifrices with fluoridated dentifrice: An in vivo study by Bhati N1, Jaidka S1, Somani R1(PubMed)
(2) Antimicrobial capacity of Aloe vera and propolis dentifrice against Streptococcus mutant strains in toothbrushes: an in vitro study by Bertolini PF1, Biondi Filho O, Pomilio A, Pinheiro SL, Carvalho MS.(PubMed)
(3) Diversity, antimicrobial and antioxidant activities of culturable bacterial endophyte communities in Aloe vera by Akinsanya MA1, Goh JK2, Lim SP2, Ting AS3.(PubMed)

Omega-3 Fatty Acids Process Anti-Mental Illness in Patients with Omega-3 Fatty Acid Deficiency

By Kyle J. Norton

Neurological disorders are a group of diseases associated with the neurons in the brain and spinal cord of the central nervous system.

The WHO in the evaluation of neurological disorders wrote, "Neurological disorders contribute to 92 million disability-adjusted life years (DALYs) in 2005 projected to increase to 103 million in 2030 (approximately a 12% increase). While Alzheimer's and other dementias are projected to show a 66% increase from 2005 to 2030".

Where one DALY represents the loss of the equivalent of one year of full health.

Believe it or not, there are more than 600 diseases of the central nervous system, including brain tumors, epilepsy, dementia such as Parkinson's disease and Alzheimer's disease, and stroke.

Mental illness is also known as mental health disorders associated with a wide range of mental health disorders, affecting all aspects of your psychological health, including mood, thinking, and behavior.

The most common mental illness in the Western world is depression, anxiety disorders, schizophrenia, eating disorders, and addictive behaviors.

There are many causes associated with the onset of mental illness, including severe psychological trauma suffered as a child, such as emotional, physical, or sexual abuse, an important early loss, such as the loss of a parent, neglect, and poor ability to relate to others.

Medical conditions such as diabetes, a  history of mental illness in a blood relative, such as a parent or sibling, and stressful life situations are some of the prevalent factors that are involved in the onset of the diseases.

Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.

The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

On finding a potential phytochemical for the treatment of psychological illnesses, researchers examined the effects of omega-3 fatty acids on the prevention and treatment of mental illness.

According to the search of the studies from 1966 to December 2010 by comparing changes in symptoms, functioning, other outcomes, and/or side effects in patients treated with omega-3 fatty acids for mental illness, intake of omega-3 fatty acids showed strong activity against mental illness in patients diagnosed with an omega-3 fatty acid deficiency.

Furthermore, the application of omega 3 fatty acids also have a strong implication against specific psychiatric disorder.

Taken altogether, Omega-3 fatty acids may be considered a functional food for the prevention and treatment of mental illness caused by omega-3 fatty acid deficiency, pending the confirmation of the larger sample size and multicenter human study.

Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) The use of omega-3 fatty acids in mental illness by Gören JL1, Tewksbury AT. (PubMed)
(2) The NEURAPRO Biomarker Analysis: Long-Chain Omega-3 Fatty Acids Improve 6-Month and 12-Month Outcomes in Youths at Ultra-High Risk for Psychosis by Amminger GP1, Nelson B2, Markulev C2, Yuen HP2, Schäfer MR2, Berger M2, Mossaheb N3, Schlögelhofer M3, Smesny S4, Hickie IB5, Berger GE6, Chen EYH7, de Haan L8, Nieman DH8, Nordentoft M9, Riecher-Rössler A10, Verma S11, Thompson A2, Yung AR12, McGorry PD. (PubMed)

Phytochemical Tocopherols, the Potential Treatment for Malaria

By Kyle J. Norton

Malaria, a mosquito-borne infectious disease caused by parasitic protozoans.

According to the statistic, malaria is one of the most common diseases in Nigeria, affecting over 97% of Nigeria's population. There are an estimated 100 million malaria cases with over 300,000 deaths per year.

Symptoms of malaria tend to occur in cycles, which correspond to the life cycle of the parasite. The most common symptoms include headaches, fatigue, muscle aches, and gastrointestinal discomforts including diarrhea.

In severe cases, patients with malaria may also experience symptoms of shortness of breath caused by fluid in the lungs and expanded abdomen caused by enlarged spleen hypoglycemia and liver diseases such as jaundice and low blood glucose.

Immune deficiency, pregnant women, newborn babies are prone to the disease if they are bitten by an infected mosquito.

Cerebral malaria is the most severe neurological complication of infection with Plasmodium falciparum malaria.

The condition is caused by coma and asexual forms of the parasite on peripheral blood smears.

Symptoms of cerebral malaria are fever, headache, body ache and progressively, delirium and coma.

Tocopherols are phytochemicals of which many have vitamin E activity, belonging to the group of Lipids, found abundantly in butter, egg yolk, milk fat, some vegetable, and seed or nut oils, etc.

On finding a potential phytochemical for the treatment of diseases associated with parasite infection, researchers examined the effect of α-TOS as an anti-malarial drug.

The study included selected C57BL/6J mice infected with P. yoelii 17XL and P. berghei ANKA, induced cerebral malaria (ECM), treated with several concentrations of α-TOS by intraperitoneal administration on 1, 3, 5, and 7 days post-infection (dpi).

According to the analysis, α-TOS treatment groups showed a significant decrease in parasitemia and improvement of the survival rate compared to a significant increase in mice infected with both parasites. 

Furthermore, the intensity of Evans blue staining associated with plasma membrane damage on brains taken from α-TOS-treated mice was weaker than that of untreated mice. 

In other words, α-TOS treatment exerted an inhibition of the breakdown of the blood-brain barrier (BBB) and the progression of cerebral malaria. 

Based on the findings, researchers said, " These findings indicate that vitamin E derivatives like α-TOS might be a potential candidate for treatment drugs against malaria"

Taken altogether, tocopherols may be considered a supplement for the treatment of malaria, pending to the confirmation of the larger sample size and multicenter human study.

Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) α-Tocopheryl succinate-suppressed development of cerebral malaria in mice by Kume A1, Kasai S2, Furuya H1, Suzuki H. (PubMed).

Phytochemical Tocopherols Suppress Esophageal Cancer Cells in Vitro

By Kyle J. Norton

An esophagus or gullet, an organ in vertebrates, is the tube that leads foods from the pharynx to the stomach.

Esophageal cancer is not very uncommonly caused by malignant of the esophagus due to abnormal cell growth as a result of the DNA alternation of the cells that line the upper part of the esophagus or glandular cells presented at the lower part of the esophagus that connected with the stomach.

Esophageal cancer tends to spread if left untreated and starts from the lining of the esophagus, then later penetrates the wall of the esophagus and spread to the lymph node around the bottom of the esophagus, stomach, and the chest, then to the distant parts of the body.

The most common types of esophageal cancer are
* Squamous cancer
In the upper part of the esophagus caused by the squamous cell of which has become malignant caused by mutation of DNA in cells replication of division uncontrollably.

* Adenocarcinomas
In the lower part of the esophagus caused by the glandular cells of which have become malignant caused by mutation of DNA in cells replication of division uncontrollably.

According to the statistics provided by the American Cancer Society, in 2019, approximately 17,650 new esophageal cancer cases will be diagnosed, including 13,750 in men and 3,900 in women.

Also, in 2019, esophageal cancer will also cause the death of 16,080 Americans, including 13,020 in men and 3,060 in women.

The 5-year survival rate of people diagnosed in the local stage of esophageal cancer is 45%, much less than other cancer, including 100% of breast cancer.

The most common areas of metastasis of esophageal cancer are the lymph node around the bottom of the esophagus, stomach, and chest.

Believe it or not, esophageal cancer is more common among men than among women. The lifetime risk of esophageal cancer in the US is 1 in 132 in men and about 1 in 455 in women.

Tocopherols are phytochemicals of which many have vitamin E activity, belonging to the group of Lipids, found abundantly in butter, egg yolk, milk fat, some vegetable, and seed or nut oils, etc.

On finding a potential phytochemical for the treatment of chronic diseases, researchers examined the preventive activity of α-Tocopherol against esophageal squamous cell carcinoma (ESCC).

According to the analysis,
* Early-stage supplementation with α-Tocopherol significantly prevented esophageal carcinogenesis induced by N-nitrosomethylbenzylamine (NMBA) in the ESCC rat model.

* In the Het-1A cell model, α-Tocopherol markedly suppressed cell proliferation, promoted cell cycle G2-phase arrest, and increased apoptosis by targeting cellular survival and growth.

* Furthermore, α-Tocopherol increased the expression of PPARγ in regulating cellular differentiation, and its downstream tumor suppressor PTEN.

Based on the results, researchers said, " These results were closely correlated with the ineffectiveness of α-Tocopherol in the late stage of ESCC carcinogenesis. Taken together, our study suggested that α-Tocopherol may serve as a PPARγ agonist for the chemoprevention of esophageal cancer".

Taken altogether, tocopherols may be considered a supplement for reducing the risk of esophageal cancer, pending the confirmation of the larger sample size and multicenter human study.

Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Alpha-Tocopherol prevents esophageal squamous cell carcinoma by modulating PPARγ-Akt signaling pathway at the early stage of carcinogenesis by Xu M#1, Yang H#2, Zhang Q2, Lu P3, Feng Y2, Geng X2, Zhang L1, Jia X. (PubMed)

Beta-Sitosterol Reduces the Risk of Liver Injury

By Kyle J. Norton

The liver is the largest internal organ in the human body, played an essential role in filtering blood from the intestine before passing them to other parts of the body.

The organ also produced cholesterol, a waxy substance that is needed to aid digestion and build strong cell membranes, production of steroid hormones and vitamins.

Liver injury may be a result caused by physical impact or penetrating trauma. In some cases, liver injury can also be induced by toxicity, leading to acute liver injury.

Liver injury can be mild or severe. In a mild case, liver injury can recover itself. However, in severe cases. surgery to stop the bleeding and remove the part of injury may be necessary.

Most cases of liver injury can lead to abdominal pain and tenderness caused by bleeding blood in the abdomen that irritates the abdominal tissue.

The severity of a liver injury can be diagnosed by computed tomography (CT) or ultrasonography.

According to the statistics, liver injury has been found to constitute 5% of all traumas, making it the most common abdominal injury.

The most common symptoms associated with liver injury are shocks due to severe bleeding inducing a rapid heart rate, rapid breathing, and cold, clammy, pale, or bluish skin.

In some cases, blood accumulated in the abdomen may irritate the abdominal tissue, leading to symptoms of abdominal pain and swelling, and tenderness.

Depending on the size of the wound, most cases of liver injury are healed by themselves. However, in severe cases, hospitalization may be necessary if the bleeding does not stop.

Out of many risk factors, an overdose of medicine has been found to be the number 1 factor involved in liver injury.

Beta-Sitosterol is a phytochemical in the class of Phytosterols, belongings to the group of Lipids, found abundantly in avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, buckwheat. etc.

On finding a potential phytochemical for the prevention and treatment of liver diseases, researchers examined the hepatoprotective effects of Beta-sitosterol (Sit) and its derivatives on acute liver injury induced by lipopolysaccharide/d-galactosamine (LPS/GalN) in mice.

According to the chemical analysis,
* Among its derivatives, 2-naphthoyl Sit ester (Sit-N) (50 mg/kg) showed the strongest activities against acute liver injury.

* More precisely, Sit-N significantly decreased the serum activity of aspartate transaminase (AST) and alanine aminotransferase (ALT) associated with liver injury

* Sit-N also markedly reduced tumor necrosis factor (TNF-α), interleukin-1β (IL-1β), and interleukin-6 (IL-6) levels involved in liver inflammation.

* Sit-N drastically improved the activities of antioxidant enzymes such as superoxide dismutase (SOD), glutathione (GSH), and catalase (CAT) and suppressed the expression of malondialdehyde (MDA), liver oxidative stress marker by increasing the expression of nuclear respiratory factor2 (Nrf2) and heme oxygenase-1 (HO-1).

Taken altogether, beta-Sitosterol may be considered a supplement for the prevention of liver injury, pending the confirmation of the larger sample size and multicenter human study.

Intake of beta-Sitosterol in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Beta-sitosterol and its derivatives repress lipopolysaccharide/d-galactosamine-induced acute hepatic injury by inhibiting the oxidation and inflammation in mice by Yin Y1, Liu X2, Liu J3, Cai E1, Zhu H4, Li H3, Zhang L1, Li P3, Zhao Y. (PubMed)
(2) Isolation and in vivo hepatoprotective activity of Melothria heterophylla (Lour.) Cogn. against chemically induced liver injuries in rats by Mondal A1, Maity TK, Pal D, Sannigrahi S, Singh J. (PubMed)

Cruciferous Vegetables Protect the Stomach Against Stomach Cancer

By Kyle J. Norton

Cancer is a class of chronic diseases associated with irregular cell growth in the tissues of the affected organ.

The stomach located between the esophagus and the small intestine is a muscular, hollow, and important organ of the digestive tract.

The stomach plays a critical role to assist the digestive system in digesting foods by secreting acid and enzymes.

Stomach cancer is a condition of abnormal growth of the mucus-producing cells of the inside lining of the stomach. Adenocarcinoma is the most common type of stomach cancer.

Most patients with stomach cancer in the early stage are asymptomatic. 

However, at the later stage, patients may experience symptoms of pain and/or discomfort in the stomach area, mild ache in the upper part of the body, difficulty swallowing, feeling full or bloated after a small mealy, and vomiting blood or having blood in the stool accompanied by general symptoms shared by other types of cancer, including unintentional weight loss, loss of energy, tiredness, nausea, and vomiting and loss of appetite.

According to the statistics, most cases of gastric/stomach cancer are found in older people. The average age of people when they are diagnosed is 68. The risk of developing gastric/stomach cancer in a man lifetime is about 1 in 95.

Localized stomach cancer has a 5-year survival rate of 68%. However, If cancer has spread to surrounding tissues or organs and/or the regional lymph nodes, the 5-year survival rate is 31%.

Cruciferous vegetables are a group of vegetables, belongings to the family Brassicaceae (also called Cruciferae) with many genera, species, and cultivated all over the world in suitable climate for commercial profits, including cauliflower, cabbage, kale, garden cress, bok choy, broccoli, Brussels sprouts, and green leafy vegetables.

On finding potential and natural foods for the prevention and treatment of cancer, researchers investigated the risk of regular cruciferous vegetable intake on stomach cancer.

The hospital-based, case-control study conducted at Roswell Park Comprehensive Cancer Center in Buffalo, NY, included 292 stomach cancer patients and 1168 cancer-free controls recruited between 1992 and 1998 as part of the Patient Epidemiology Data System (PEDS).

According to the dietary and other epidemiologic and confounding variables collected by the questionnaire, there were strong inverse associations between stomach cancer and the highest versus lowest intakes of total cruciferous vegetables with the odds ratio (OR) of 0.59.

In the comparison test assay, raw cruciferous vegetables have an OR = 0.53, compared to raw broccoli with an OR = 0.61, raw cauliflower with an OR = 0.51, and Brussels sprouts with an OR = 0.66.

Increased portions of total cruciferous vegetable intake are associated linearly to a reduced risk of stomach cancer.

After taking other factors into account, researchers wrote, "These data suggest that consuming raw cruciferous vegetables may be associated with a lower odds of stomach cancer, even after considering other dietary characteristics".

Taken altogether, dietary cruciferous vegetables may be considered functional remedies for the prevention of stomach cancer, pending the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Cruciferous Vegetable Consumption and Stomach Cancer: A Case-Control Study by Morrison MEW1, Joseph JM2, McCann SE2, Tang L2, Almohanna HM2, Moysich KB. (PubMed)

Tocopherols Promote Cytotoxic Activity Against Cancer Cells

By Kyle J. Norton


Cytotoxicity is the process that induces cell death through toxins.

In other words, cell cytotoxicity is the process to use certain chemicals or mediator cells to destroy the living cells.

In normal, cytotoxicity can cause the death of healthy cells

In cancers, cytotoxicity can be beneficial to humans by destroying the cancer cells and preventing them from proliferation.

For example, cytotoxicity induced by oxidative stress due to the imbalanced ratio of free radicals and antioxidant enzymes produced by the body can cause protein, lipid, and cellular damage that leads to chronic low-grade inflammatory diseases and cancer.

However, stimulation of ROS expression to induce cytotoxicity to the tumors can also cause cancer cell death without damage to nearby healthy cells.

Scientifically, most cases of cancer cell cytotoxicity are associated with the stimulation of protein and pathways involved in either gene suppression or cell death programming.

Chemotherapy is a type of cancer treatment that uses one or more toxic chemicals to kill cancer cells.

Chemotherapeutic cytotoxicity is the process that interferes with cell division (mitosis) through cell cycle arrest to include apoptosis.

Tocopherols are phytochemicals of which many have vitamin E activity, belonging to the group of Lipids, found abundantly in butter, egg yolk, milk fat, some vegetable, and seed or nut oils, etc.

On finding a potential phytochemical for the treatment of cancer researchers examined protective effects of α- and γ-tocopherols and α- and γ-tocotrienols on the oxidative stress induced by LPS on human lung carcinoma A549 cells.

Application of α- and γ-tocopherols and α- and γ-tocotrienols showed strong suppression of the intracellular reactive oxygen formation, lipid peroxidation, and induction of inflammatory mediator cytokines, and cell death.

More precisely, the application of tocopherols incorporated into cultured cells could suppress LPS-induced oxidative stress at much lower intracellular concentration than tocotrienols compared to the much slower tocotrienols.

In other words, tocopherols demonstrated the strongest cytotoxicity against the tested cancer cells compared to that of tocotrienols.

Collectively, researchers wrote, "α-tocopherol may exhibit the highest protective capacity among the vitamin E isoforms against LPS-induced oxidative stress".

Taken altogether, tocopherols may process cytotoxicity against the onset of cancer, pending the confirmation of the larger sample size and multicenter human study.

Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Attenuation of lipopolysaccharide (LPS)-induced cytotoxicity by tocopherols and tocotrienols by Nishio K1, Horie M, Akazawa Y, Shichiri M, Iwahashi H, Hagihara Y, Yoshida Y, Niki E. (PubMed)

Antioxidant Alliin Isolated From Garlic May Processes Immunomodulatory Effects

By Kyle J. Norton

The immunomodulatory effect is an action in which the immune function is modulated to the needs of the body.

The immune system included the thymus and bone marrow, as well as secondary lymphatic tissues including the spleen, tonsils, lymph vessels, lymph nodes, adenoids, skin, and liver, which is the body's defense against infectious organisms and foreign invaders.

In the acute phase of infection, the immune macrophages, the first line of defense stimulate the production of a blood palette to cover the wound or injury and pro-inflammatory cytokines to the site of infection to kill off pathogens before they can enter the body to multiply.

Most cases of infection are stopped at the acute phase, depending on the size and penetration of the wound.

However, if the immune system for whatever reason such as in people with a weakened immune system can not destroy the foreign invaders in the set period of time (3-8 weeks), it will adapt to the new change, leading to chronic low-grade inflammation.

Low-grade inflammation over time has been found to destroy cells and tissues in the affected area or organ, inducing chronic inflammatory disease, including diabetes, arthritis, and cardiovascular disease.

Out of many low-grade inflammatory risk factors, some researchers suggested that an unhealthy diet may be one of the major culprits involved in facilitating the onset of the diseases.

Dr. Casas R, Sacanella E, the lead scientist wrote, "Dietary patterns high in refined starches, sugar, and saturated and trans-fatty acids, poor in natural antioxidants and fiber from fruits, vegetables, and whole grains, and poor in omega-3 fatty acids may cause an activation of the innate immune system, most likely by excessive production of proinflammatory cytokines associated with a reduced production of anti-inflammatory cytokines".

In other words, if you follow the diet pattern of a high-fat diet, you are at a higher risk of low-grade inflammatory disease, compared to those who follow the diet pattern of the Mediterranean diet.

Alliin (S-allyl-L-cysteine-S-oxide) is a phytochemical compound sulfoxide,. a derivative of the amino acid cysteine, belongings to the class of sulfur compounds, found abundantly in fresh garlic and onion.

With an aim to find a natural ingredient with immunomodulatory activity, researchers examined the effect of the garlic derivative alliin, on mitogen-induced peripheral blood mononuclear cell (PBMC) proliferation and cytokine production in vitro.


Before being treated with garlic derivative alliin, pokeweed mitogen (PWM) injection induced cell proliferation, production of proinflammatory cytokines, including IL-1beta and TNF-alpha.

Furthermore, the pokeweed mitogen (PWM) treated group also showed reduced levels of both percentage of phagocyting cells and the number of latex particles associated with the immune functions of phagocytosis.

Administration of garlic derivative alliin not only decreased the production of proinflammatory cytokines induced by pokeweed mitogen (PWM) but also improved the levels of antioxidant enzymes.


In other words, alliin exerted an immunomodulatory effect on the peripheral blood cells in vitro.


In order to reveal more information of alliin effect on the immune system, researchers investigated whether different plant-derived components with similar anti-oxidative and anti-inflammatory function such as quercetin and alliin in traditional Asian diet consumed in an alternate style cooperatively affect health including the growth of host and the status of the gut microbiota and colonic epithelial immunity.

Compared to the traditional Asian diet significantly increased the rat body weight and reshaped the gut microbiota composition by significantly increasing the relative abundance of fecal Firmicutes and Cyanobacteria but decreased that of Bacteroidetes (P < 0.05) and increased the relative abundance of Candidatus Arthromitus, Lactococcus, Geobacillus, and Ruminococcus at the genus level that benefits the host's health, the consumption of quercetin and alliin also altered 13 genes expression involved in the KEGG pathways of complement and coagulation cascades and hematopoietic cell lineage to improve the gut immunity.

In other words, the alternate consumption of quercetin and alliin can contribute beneficial metabolic effects by optimizing gut microbiota and altering the immunologic function of colonic epithelial cells.

Taken altogether, alliin may be considered supplements for the immune-modulatory activity depending on the body needs, pending the confirmation of the larger sample size and multicenter human study.

Intake of alliin in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Effect of a garlic derivative (alliin) on peripheral blood cell immune responses by Salman H1, Bergman M, Bessler H, Punsky I, Djaldetti M. (PubMed)
(2) The Alternate Consumption of Quercetin and Alliin in the Traditional Asian Diet Reshaped Microbiota and Altered Gene Expression of Colonic Epithelial Cells in Rats by Yu J1, Guo H1, Xie J1, Luo J1, Li Y1, Liu L1, Ou S1, Zhang G1, Peng X. (PubMed)
(3) The immune protective effect of the Mediterranean diet against chronic low-grade inflammatory diseases by Casas R, Sacanella E, Estruch R. (PubMed)

Cruciferous vegetables Kill Non-Small Cell Lung Cancer in Vitro

By Kyle J. Norton

The lung is a vital organ of the human being, located near the backbone on either side of the heart with functions of inhaling oxygen from the air then transporting them to the bloodstream to nourish the body cells' needs and exhaling carbon dioxide from the bloodstream.

Cancer is a class of disease characterized by cell growth disorderly and uncontrollably in the tissues and organs.

Lung cancer is a medical condition characterized by abnormal growth of the cells in the lung's tissue.

The most common form of primary lung cancers is derived from epithelial cells.

According to the statistics provided by the American Cancer Society, in the US, lung cancer is the leading cause of cancer deaths.

In 2007, lung cancer causes the death of 158,683 people, including 88,329 men and 70,354 women.

In other words, 1 in 16 people in the US will be diagnosed with lung cancer in their lifetime. Approximately over 220,000 people in the US will be diagnosed with lung cancer this year.

Believe it or not, 60% to 65% of all new lung cancer diagnosed are among people who have never smoked or are former smokers.

Non-small cell lung cancer, the most common type of lung cancer, usually grows and spreads methodically and predictably.

The most common risk factors of non-small cell lung cancer (NSCLC) are long term smoking and people exposed to long-term second-hand smoke.

The most common symptoms of lung cancer are shortness of breath, cough up blood, pain, fluid in the chest, wheezing and hoarseness accompanied by general symptoms shared by other types of cancer.


Cruciferous vegetables are a group of vegetables, belongings to the family Brassicaceae (also called Cruciferae) with many genera, species, and cultivated all over the world in suitable climate for commercial profits, including cauliflower, cabbage, kale, garden cress, bok choy, broccoli, Brussels sprouts, and green leafy vegetables.

On finding a potential compound for the prevention and treatment of cancer, researchers examined
the effect of the combination of two isothiocyanates, i.e. allyl isothiocyanate and sulforaphane on A549 lung cancer cells.

According to the results of the experiment, the combination treatment worked synergistically to induce stronger growth inhibition of the cancer cells compared to the singular treatment.

The combination treatment caused cell cycle arrest, suppressed cell migration and apoptosis compared to a singular treatment by modifying the expression of key proteins associated with the cellular processes.

Most importantly, the combined treatment also exhibited the expression of ROS to induce the cytotoxic activity against the tested cell line.

Based on the findings, researchers said, "our results have demonstrated the potential of different isothiocyanates used in combination to produce enhanced protective effects against carcinogenesis".

Taken altogether, cruciferous vegetables processed a high amount of allyl isothiocyanate and sulforaphane may be considered functional foods for the prevention of non-small cell lung cancer pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Synergistic chemopreventive effect of allyl isothiocyanate and sulforaphane on non-small cell lung carcinoma cells by Rakariyatham K 1, Yang X, Gao Z, Song M, Han Y, Chen X, Xiao H. (PubMed)