Kyle J. Norton
The liver is the largest internal organ found in the human which plays an essential role in filtering the blood from the digestive system before passing it to other parts of the body.
The liver also produces cholesterol, a waxy substance that aids digestion, builds cell membranes and produces vitamin D and steroid hormones.
Liver protection is an action in which substances including medicine and herbal remedy were used to protect the liver against damage.
Liver disease is a broad term that includes any problems that cause the reduced function of the liver.
There are many risk factors that liver problems. Most cases of liver disease are diagnosed in the advanced stage, it takes years to develop.
There is no single cause of liver disease. Researchers suggested that viruses such as hepatitis A, B, and C, long-term excessive alcohol drinking, and genetic mutation inherited from the parents are the major risk factors associated with the early onset of the diseases.
Some researchers suggested overweight and obese and congenital diseases such as Hemochromatosis and Wilson’s disease also are prevalent risk factors for liver damage and diseases.
Liver damage and disease can also be caused by long-term intake of certain medications, such as paracetamol, and Illegal drugs such as cocaine.
The most common symptoms of liver disease can be felt only after more than 75% of the liver is damaged, including persistent jaundice and gastrointestinal discomforts, abdominal pain, and swelling, leg and ankle swelling, itching, and pale color of stool.
The most common risk factors are genetic predisposition, viruses, and long-term excessive alcohol drinking.
According to the statistics, the mortality rate infected by viral hepatitis has increased by 63% from 890,000 in 1990 to 1.45 million in 2013, according to a review of data collected in 183 countries.
Broccoli is a mustard/cabbage plant, belonging to the family Brassicaceae. The veggie has large flower heads, usually green in color with a mass of flower heads surrounded by leaves and evolved from a wild cabbage plant from the continent of Europe.
With an aim to find a natural food for the prevention and treatment of liver diseases, researchers examined the effect of combined therapy with Indian mustard and broccoli on rats' liver-induced hepatotoxicity by long-term vincristine (VCR)
According to the results of rats selected for the study induced liver toxicity by
* Vincristine (VCR) treated group showed signs of hepatotoxicity, including altered liver architecture and higher serum levels of liver stress markers ALT and AST.
* Vincristine (VCR) treated group also showed an impaired antioxidant potential and higher mRNA levels of IL-12 and IL-4, which are markers of apoptosis in rat livers.
In other words, VCR treatment-induced hepatocyte apoptosis by stimulating the levels of apoptotic proteins and pathways.
Most importantly, the treatment of individual administration of mustard or broccoli partially ameliorated all these responses, compared to maximum improvement in the combined therapy of both extracts.
Based on the results, researchers wrote, " Thus, the long-term administration of VCR is hepatotoxic and induces apoptosis; however, the combined therapy of both extracts mitigated these effects"
Taken altogether, broccoli may be considered a liver protective supplement, pending the confirmation of the larger sample size and multicenter human study.
Intake of SFN in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Hepatotoxic effect of subacute vincristine administration activates necrosis and intrinsic apoptosis in rats: protective roles of broccoli and Indian mustard by Shati AA1, Elsaid FG. (PubMed)
No comments:
Post a Comment