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Polycystic Ovarian Syndrome
Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovasular disease(8)(13), acne(10)(14), endometrial cancer(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women. Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasing altered glucose tolerance(20), CVD and hypertension(21).
In Traditional Chinese Medicine Perspective
While conventional medicine focus of using synthetic medication to induce ovulation and assisted artificial insemination for infertility couple, if the medicine fail, traditional Chinese medicine views polycystic ovarian syndrome in different approaches. Polycystic ovary syndrome, according to traditional Chinese medicine is a medical condition characterized by accumulative of fluid over a prolonged period of time causes of dampness and phlegms(1247a)(1247b) build up on the ovaries due to the effects of vary differentiations, affecting not only the women’s menstrual cycle, but also ovulation and fertility(1247a)(1247b).
PCOs Treatment according traditional Chinese medicine
Depending to differentiation, most common diagnosis of polycystic ovary syndrome can be classified into
Spleen yang deficiency
Spleen yang deficiency is a serve form of spleen qi deficiency, characterized by a condition of inability of spleen in distribution of fluid and nutrient to the body organs, in removal and descend the turbids(2072), causing malfunctions functions of the organs and fluid retention. Prolong period of spleen yang deficiency may induce the development of phlegm, including women with PCOs.
Women with PCOs diagnosed by spleen yang deficiency may also experience yang vacuity impelled cold expression of additional symptoms of abdominal pain(2074), lack of appetite(2076), fatigue(2075), lightheadedness(2075) and headache(2075), weakness of the four limbs(2077), diarrhea(2073)(2076), chilliness(2077), edema(2074), pale, swollen, wet tongue(2076) and weak, slow, deep pulse(2072),....
In the review of the Data base provided by PubMed, spleen qi deficiency may alter certain metabolic pathways, such as the energy, protein, and glycolytic metabolisms(2078), body weight and motor behavior(2079), skeletal muscle function(3080), blood glucose, lipid metabolism and fat-islet axie.(2081),.....
Women with PCOs diagnosed by spleen yang deficiency may also experience yang vacuity impelled cold expression of additional symptoms of abdominal pain(2074), lack of appetite(2076), fatigue(2075), lightheadedness(2075) and headache(2075), weakness of the four limbs(2077), diarrhea(2073)(2076), chilliness(2077), edema(2074), pale, swollen, wet tongue(2076) and weak, slow, deep pulse(2072),....
In the review of the Data base provided by PubMed, spleen qi deficiency may alter certain metabolic pathways, such as the energy, protein, and glycolytic metabolisms(2078), body weight and motor behavior(2079), skeletal muscle function(3080), blood glucose, lipid metabolism and fat-islet axie.(2081),.....
Foods for Spleen yang deficiency
Spleen yang deficiency can be managed and treated in part with a diet of fresh and cooked warming foods.
2. Ginger(1616) (See kidney yin deficiency for more information)
Jiang is also known as Ginger root. The acrid and warm herb has been use in TCM as an anti inflammation(1618)(1619)(1620), anti coagulation of platelets(1621)and anti thrombotic(1622), anti allergy(1625)(1626), anti tumors(1627)(1628) and anti hair growth(1629)(1630) lower back painpain(1623)(1624), functional bowel disorders (FBD(1631), etc., as it warms the middle burner and lungs, rescues yang, transforms phlegm by enhancing the functions of lung, spleen and stomach channels(1617).
Chemical constituents
1. 2-heptanol
2. 1,3,3-trimethyltricyclo[2,2,1,0] heptane
3. Tricycline
4. β-fenchene
5. β-pinene
6. 5-hepten-2-one-6-mehtyl
7. Myrcene
8. Octanal
9. α-thujene
10. Zingiberol
11. Zingiberene
12. α-curcumene
13. linalool
14. Cineole
15. Phellandrene
16. Camphene
17. Etc.(1617)
Strong evidences from epidemiological literature suggested that ginger also consist the properties of anti obesity(1632)(1636), anti insulin resistance(1632)01636), anti (1634)(1636), anti dyslipidaemia(1634)(1636), anti diabetes(1635)(1637) and reduced risk the metabolic syndrome causes of cardiovascular complications(1634), etc,....
Its major chemical component, [6]-gingerol analogue (6G), and extracts in rat study exhibited the protective effect against the development of metabolicsyndrome(1633)(1636), through significantly reduced body weight gain(1633)(1636), fat accumulation(1633)(1636), and circulating levels of insulin(1636)(1633) and leptin(1633).
Through its warm in nature and effects on metabolic syndrome, ginger is recommended to the daily diet of PCOs' women diagnosed with kidney yang deficiency by traditional Chinese medicine.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndrome and healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women WithPolycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(1246) [Clinical study of area of Jiangsu province of polycystic ovarian syndrome correlation distribution of traditional Chinese medicine syndrome type and improper diet]. [Article in Chinese] by Feng Y, Gao YP.(PubMed)
(1247) [Preliminary study on relationship of disease-syndrome-symptom of ovulatory disorder infertility based on factor analysis]. [Article in Chinese] by Li M, Ma K, Shan, J.(PubMed)
(1247a) A Comprehensive Treatment of Polycystic Ovarian Syndrome (PCOS) bny by Liqin Zhao
(2072) Spleen, Earth
(2073) [Research on building method of spleen kidney Yang deficiency diarrhea rats model]. [Article in Chinese] by Pan X, Hu CJ, Geng YY, Zhao L, Wu WH, Wu XQ, Zhong ZD.(PubMed)
(2074) Treatment of an elderly patient with acute abdominal pain with traditional Korean medicine by Son CG1.(PubMed)
(2075) Shenzhu Tiaopi granule combined with lifestyle intervention therapy for impaired glucose tolerance: a randomized controlled trial by Fang Z1, Zhao J2, Shi G3, Shu Y3, Ni Y3, Wang H3, Ding L3, Lu R3, Li J3, Zhu X3, Cheng S4, Zhang X3, Liu Y5, Wang J6, Luo Y3, Fan Q3, Guo C3, Jiang T3, Wu Q3, Fan L3, Ling H3, Cui L3, Luo Y3, Yang H3, Anderson RM7.(PubMed)
(2075) Direct moxibustion to treat spleen qi and yang deficiency fatigue: a pilot study by Thorne TL1, Hanes DA2, Wild H3, Colbert A4.(PubMed)
(2076) [Clinical observation on fuzhong (supporting the middle-jiao) manipulation of tuina for infantile anorexia]. [Article in Chinese] by Wang YY, Liu XY.(PubMed)
(2077) [Effect of umbilicus moxibustion therapy on physical conditions of yang-deficiency volunteers]. [Article in Chinese] by Zhang YY1.(PubMed)
(2078) Analysis of the restorative effect of Bu-zhong-yi-qi-tang in the spleen-qi deficiency rat model using (1)H-NMR-based metabonomics by Zheng XF1, Tian JS2, Liu P3, Xing J1, Qin XM1.(PubMed)
(2079) [1H NMR based metabolomics study of bu-zhong-yi-qi-tang in the spleen-qi deficiency rat model]. [Article in Chinese] by Chen L, Xiang H, Xing J, Tian JS, Qin XM, Du GH.(PubMed)
(2080) Bufei Jianpi granules improve skeletal muscle and mitochondrial dysfunction in rats with chronic obstructive pulmonary disease by Dong Y1,2, Li Y3,4,5, Sun Y6, Mao J7, Yao F8, Tian Y9, Wang L10, Li L11, Li S12,13,14, Li J15,16,17(PubMed)
(2081) [Clinical observation on obesity and hyperlipidemia of liver qi stagnation and spleen deficiency pattern in female patients treated with combined therapy of acupuncture and tapping method]. [Article in Chinese] by Wu B, Liu ZC, Xu B.(PubMed)
(1616) Chinese Herbs – Jiang (Rhizoma zingiberis officinalis) by Kyle J. Norton
(1617) Jiang(Complementary and Alternative Healing University)
(1618) Influence of ginger and cinnamon intake on inflammation and muscle soreness endued by exercise in Iranian female athletes by Mashhadi NS1, Ghiasvand R, Askari G, Feizi A, Hariri M, Darvishi L, Barani A, Taghiyar M, Shiranian A, Hajishafiee M.(PubMed)
(1619) Dietary influence on pain via the immune system by Totsch SK1, Waite ME1, Sorge RE2.(PubMed)
(1620) Anti-inflammatory effects of zingiber officinale in type 2 diabetic patients by Mahluji S1, Ostadrahimi A, Mobasseri M, Ebrahimzade Attari V, Payahoo L.(PubMed)
(1621) Anticoagulant activity of select dietary supplements by Stanger MJ1, Thompson LA, Young AJ, Lieberman HR.(PubMed)
(1622) Antithrombotic effects of naturally derived products on coagulation and platelet function by Mousa SA1.(PubMed)
(1623) The effectiveness of Swedish massage with aromatic ginger oil in treating chronic low back pain in older adults: a randomized controlled trial by Sritoomma N1, Moyle W2, Cooke M3, O'Dwyer S4.(PubMed)
(1624) Evidence of effectiveness of herbal antiinflammatory drugs in the treatment of painful osteoarthritis and chronic low back pain by Chrubasik JE1, Roufogalis BD, Chrubasik S.(PubMed)
(1625) In vitro and in vivo anti-allergic effects of 'benifuuki' green tea containing O-methylated catechin and ginger extract enhancement by Maeda-Yamamoto M1, Ema K, Shibuichi I.(PubMed)
(1626) Ginger prevents Th2-mediated immune responses in a mouse model of airway inflammation by Ahui ML1, Champy P, Ramadan A, Pham Van L, Araujo L, Brou André K, Diem S, Damotte D, Kati-Coulibaly S, Offoumou MA, Dy M, Thieblemont N, Herbelin A.(PubMed)
( 1627) Ginger extract (Zingiber officinale) has anti-cancer and anti-inflammatory effects on ethionine-induced hepatoma rats by Habib SH1, Makpol S, Abdul Hamid NA, Das S, Ngah WZ, Yusof YA.(PubMed)
(1628) Chemopreventive efficacy of ginger (Zingiber officinale) in ethionine induced rat hepatocarcinogenesis by Yusof YA1, Ahmad N, Das S, Sulaiman S, Murad NA.(PubMed)
(1629) 6-Gingerol inhibits hair shaft growth in cultured human hair follicles and modulates hair growth in mice by Miao Y1, Sun Y, Wang W, Du B, Xiao SE, Hu Y, Hu Z.(PubMed)
(1630) [Inhibition effect of 6-gingerol on hair growth].[Article in Chinese] by Miao Y, Sun YB, Wang WJ, Zhang ZD, Jiang JD, Li ZH, Hu ZQ.(PubMed)
(1631) Complementary and alternative medicine use and cost in functional bowel disorders: a six month prospective study in a large HMO by van Tilburg MA1, Palsson OS, Levy RL, Feld AD, Turner MJ, Drossman DA, Whitehead WE.(PubMed)
(1632) Targeting inflammation-induced obesity and metabolic diseases by curcumin and other nutraceuticals by Aggarwal BB1.(PubMed)
(1633) Synthesis of a new [6]-gingerol analogue and its protective effect with respect to the development of metabolic syndrome in mice fed a high-fat diet by Okamoto M1, Irii H, Tahara Y, Ishii H, Hirao A, Udagawa H, Hiramoto M, Yasuda K, Takanishi A, Shibata S, Shimizu I.(PubMed)
(1634) Modulatory effects of garlic, ginger, turmeric and their mixture on hyperglycaemia, dyslipidaemia and oxidative stress in streptozotocin-nicotinamide diabetic rats by Madkor HR1, Mansour SW, Ramadan G.(PubMed)
(1635) Comparative effects of dietary ginger (Zingiber officinale) and garlic (Allium sativum) investigated in a type 2 diabetes model of rats by Islam MS1, Choi H.(PubMed)
(1636) Protective effects of ethanolic extract of Zingiber officinale rhizome on the development of metabolic syndrome in high-fat diet-fed rats by Nammi S1, Sreemantula S, Roufogalis BD.(PubMed)
(1637) The anti-oxidant effects of ginger and cinnamon on spermatogenesis dys-function of diabetes rats by Khaki A1, Khaki AA1, Hajhosseini L2, Golzar FS1, Ainehchi N1(PubMed)
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