Wednesday 5 July 2023

The #Anti #BenignProstaticHyperplasia(BPH) WholeFruits, Researchers Suggest

Kyle J. Norton

Benign prostatic hyperplasia(BPH) is a condition characterized by the increased number of cells of the prostate gland, causing partial, or sometimes virtually complete obstruction of the urinary tract.
According to statistics, BPH commonly starts at the age of 30 and symptoms usually can not be realized until the age of 50.

More than half of men between age of 60-70 experience some symptoms of BPH and only 10% are required treatment.

A suggestion of BPH is associated with nutritional status and eating habits.

According to the study, 30 male patients with clinically confirmed and treated disease of the prostatic gland, including 15 men (aged 51-75 years) with BPH and 15 men (aged 51-73 years) with PC, improper nutritional status induced incorrect nutritional habits, maybe the cause of the development of some diet-dependent diseases, such as BPH and prostate cancer(a).

A proper diet with vegetables, fruit containing zinc may reduce the risk of the disease from initiation(b)(c).

Epidemiological studies strongly suggested that the intake of vegetables and fruits accompanied with a healthy lifestyle is associated with reduced risk and treatment of enlarged prostate(d)(e)(f), through enhancing antioxidant activity in inhibited overproduction of prostate cells(g)(h).

4 Fruits for reducing risk of Benign prostatic hyperplasia(BPH)
1. Orange
Orange is a species of Citrus Sinensis, belongings to the family Rutaceae and native to Southeast Asia.

According to the study, the extract of red orange juice (ROE) inhibited the proliferation of fibroblast and epithelial prostate cells in patients with benign prostatic hyperplasia(22).

2. Watermelon and strawberry
Lycopene, a member of the carotenoid family, found abundantly in Watermelons, and strawberries, exerted a significant antioxidant effect against the formation of prostate disease(23).

The study of Profluss® included serenoa repens+Selenium+Lycopene on prostatic chronic inflammation (PCI) in 168 subjects, the compositions exhibited anti-inflammatory activity for the treatment of PCI in BPH and/or PIN/ASAP patients(24).

In injection of Serenoa repens, lycopene, and selenium were superior to Serenoa repens alone in reducing benign prostatic hyperplasia, through reduction of prostate weight, hyperplasia, cell proliferation, and growth factor in augmentation of apoptosis(25) compared to other treatment groups.

3. Cranberry
Cranberry is a species of Vaccinium oxycoccos, belongings to the family Ericaceae.

In the study to evaluate the efficacy and tolerability of cranberry (Vaccinium macrocarpon) powder in men at risk of prostate disease with lower urinary tract symptoms (LUTS), researchers suggested that the application displays a positive effect in lower total PSA level on day 180 of the study(26) and reduced urinary tract symptoms of benign prostatic hyperplasia(27).

Furthermore cranberry also found to reduce symptoms of dysuria, nocturia, urinary frequency and urgency) in a group of 270 BPH patients(28).

Taken together, the evidence finding postulated that adding some portions of orange, watermelon, strawberry, and cranberry may have a potential effect in reduced symptoms, risk, progression, and treatment of benign prostatic hyperplasia(BPH).


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.

References
(a) Nutritional status and nutritional habits of men with benign prostatic hyperplasia or prostate cancer - a preliminary investigation by Goluch-Koniuszy Z, Rygielska M, Nowacka I.(PubMed)
(b) Diet and benign prostatic hyperplasia: a study in Greece by Lagiou P1, Wuu J, Trichopoulou A, Hsieh CC, Adami HO, Trichopoulos D.(PubMed)
(c) Associations of obesity, physical activity, and diet with benign prostatic hyperplasia and lower urinary tract symptoms by Raheem OA1, Parsons JK. (PubMed)
(d) Nutrition and benign prostatic hyperplasia by Espinosa G.(PubMed)
(e) Dietary patterns and prostatic diseases by Sebastiano C1, Vincenzo F, Tommaso C, Giuseppe S, Marco R, Ivana C, Giorgio R, Massimo M, Giuseppe M.(PubMed)
(f) Fruit and vegetable consumption, intake of micronutrients, and benign prostatic hyperplasia in US men by Rohrmann S1, Giovannucci E, Willett WC, Platz EA. (PubMed)
(22) Effect of a standardized extract of red orange juice on proliferation of human prostate cells in vitro by Vitali F1, Pennisi C, Tomaino A, Bonina F, De Pasquale A, Saija A, Tita B.(PubMed)
(23) Lycopene for the prevention and treatment of prostate disease by Ilic D.(PubMed)
(24) Effects of Serenoa repens, selenium and lycopene (Profluss®) on chronic inflammation associated with benign prostatic hyperplasia: results of "FLOG" (Flogosis and Profluss in Prostatic and Genital Disease), a multicentre Italian study by Morgia G1, Cimino S, Favilla V, Russo GI, Squadrito F, Mucciardi G, Masieri L, Minutoli L, Grosso G, Castelli T.(PubMed)
(25) [The association of Serenoa repens, lycopene, and selenium is superior to Serenoa repens alone in reducing benign prostatic hyperplasia].[Article in Italian] by Squadrito F1, Morgia G.(PubMed)
(26) The effectiveness of dried cranberries ( Vaccinium macrocarpon) in men with lower urinary tract symptoms by Vidlar A1, Vostalova J, Ulrichova J, Student V, Stejskal D, Reichenbach R, Vrbkova J, Ruzicka F, Simanek V.(PubMed)
(27) Risk factors for lower urinary tract symptoms suggestive of benign prostatic hyperplasia in a community-based population of healthy aging men: the Krimpen Study by Kok ET1, Schouten BW, Bohnen AM, Groeneveld FP, Thomas S, Bosch JL.(PubMed)
(28) Enteric-coated, highly standardized cranberry extract reduces risk of UTIs and urinary symptoms during radiotherapy for prostate carcinoma by Bonetta A1, Di Pierro F.(PubMed)

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