Respiratory Disease is a medical condition which affects the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing, etc.
The lungs are a pair of organs located on either side of the chest (thorax) with a function to bring fresh oxygen into the body and remove carbon dioxide and other waste gases from the body.
According to the statistics provided by the Lung Association over 3 million Canadians are affected by one of five serious respiratory diseases – asthma, chronic obstructive pulmonary disease (COPD), lung cancer, tuberculosis (TB), and cystic fibrosis.
In 2017, 28,600 Canadians were diagnosed with lung cancer, representing 14% of all new cancer cases. Lung cancer caused the death of 21,100 Canadians in the same year.
Asthma is a chronic inflammatory disease affecting the airway of the lung with recurring symptoms, such as wheezing, chest tightness, shortness of breath, and coughing. The disease affects people of all ages and mostly starts during childhood.
Besides episodes of wheezing, coughing, chest tightness, and shortness of breath, patients with asthma also experience symptoms of reversible airflow obstruction and bronchospasm.
Asthma attack in most cases is triggered by exposure to various irritants and substances that trigger allergies (allergens). However, genetic preposition and family history are also found in patients with asthma.
Asthma in some cases can interfere with daily activities and may lead to a life-threatening asthma attack. Treatment of asthma is to reduce the frequent episode and severity of the attacks.
According to the statistics provided by the Centers for Disease Control and Prevention (CDC), in the US, 1 in 13 people have asthma. In other words, over 26 million Americans have asthma and half of that is children.
Believe it or not, African-Americans in the U.S. die from asthma at a higher rate than people of other races or ethnicities.
Broccoli is a mustard/cabbage plant, belongings to the family Brassicaceae. The veggie has large flower heads, usually green in color with a mass of flower heads surrounded by leaves and evolved from a wild cabbage plant from the continent of Europe.
With an aim to find a natural food for the prevention and treatment of respiratory diseases, researchers examined the effect of Broccoli sprouts (BS) on airway inflammatory and physiologic outcomes, and OS in adults with asthma and allergic sensitization to an indoor allergen.
A double-blind, placebo-controlled, randomized trial to compare the effects of BS with placebo (alfalfa sprouts [AS]) on airway inflammation and markers of OS included 40 adults (aged 18-50 years) who were randomized to eat either (a) 100 g of BS daily or (b) 100 g of AS daily for 3 days.
According to the tested analysis,
* BS ingestion for 3 consecutive days did not reduce FeNO in asthma, despite causing a marked increase in serum SFN concentrations (21 vs 22 parts per billion, P = .76).
* Furthermore, BS administration did not induce cytoprotective antioxidant genes in either PBMCs or nasal epithelial cells,
* Moreover, BS consumption did not reduce OS and inflammatory markers or improve lung function.
In other words, short term interference of BS showed no improvement of the symptoms on asthmatic patients
Based on the results, researchers wrote, " Ingestion of the whole BS for 3 days does not appear to improve eosinophilic pulmonary inflammation, inflammatory and OS biomarkers, or clinical features of asthma among atopic adults with asthma despite resulting in a marked increase in serum SFN levels."
And "However, because variability exists in the timing and methods of detection for SFN conjugate levels, it is difficult to compare systemic SFN levels across studies".
Intake of SFN in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as they international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) A Randomized Controlled Trial of the Effect of Broccoli Sprouts on Antioxidant Gene Expression and Airway Inflammation in Asthmatics by Sudini K1, Diette GB2, Breysse PN3, McCormack MC2, Bull D4, Biswal S5, Zhai S4, Brereton N6, Peng RD7, Matsui EC. (PubMed)
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