Intake of coffee may have a profound effect in strengthening the telomere length, a biomarker of living longer, some researchers suggested.
The results of the investigation based on the medical guideline and criteria were carried out by some universities, including the National Cancer Institute and Brigham and Women's Hospital, and Harvard Medical School.
Coffee, second to tea consumption, is a popular and social beverage all over the world, particularly in the West, made from roasted beans from the Coffea plant, native to tropical Africa and Madagascar.
In a cross-sectional association between coffee consumption and telomere length in 4780 women, using the data from the Nurses' Health Study (NHS) from a prospective cohort study of female nurses began in 1976 with relative telomere length measured in peripheral blood leukocytes by the quantitative real-time polymerase chain reaction, after adjusting to other risk factors, researchers found that
* Higher total coffee use was significantly associated with longer telomeres compared to non-drinkers.
* Intake of 2 to <3 and ≥3 cups of coffee/d showed a relative ratio of 1.29 and 1.36, respectively.
* Telomere length was associated linearly with caffeine consumption from all dietary sources
The findings showed a strong indication of a correlation between coffee caffeine intake and the length of telomeres among female nurses.
Dr. Liu JJ, the lead author said, " ... better understand the influence of coffee consumption on telomeres, which may uncover new knowledge of how coffee consumption affects health and longevity".
Furthermore, in the differentiation to re-confirm the effects of coffee drinking on increased life expectancy, Brigham Young University also conducted a study obtained data to examine the coffee longevity efficacy from 5826 adults from the National Health and Nutrition Examination Survey (NHANES) cross-sectionally,
In a total of 5826 adults, using the quantitative polymerase chain reaction method, telomere length compared to standard reference DNA, after adjusting to other risk factors, including age, gender, race, marital status, education, housing, smoking, BMI, physical activity, alcohol use,.. researchers showed that
* Caffeine consumption was inversely related to telomere length.
* For each 100 mg of caffeine consumed, telomeres were 35.4 base pairs shorter.
* For each 100 mg of caffeine consumed among coffee drinkers only, telomeres were 36.7 base pairs shorter.
* Among non-coffee drinkers only, 40.0 base pairs are shorter.
Compared to nondrinker {(40.0 base pairs shorter), coffee caffeine( 36.7 base pairs shorter), and caffeine( 35.4 base pairs shorter)} coffee intake expressed a positive effect in reduced genetic telomeres lengths much slower.
In other words, coffee caffeine drinkers have had a longer life expectancy compared to only coffee or caffeine drinkers and nondrinkers
Taking together, coffee (regardless caffeinated or not and the number of cups intake per day) expressed a significant effect in enhanced longevity through modulating the DNA implication of living longer in both genders.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, healthblogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299
Sources
(1) Coffee Consumption Is Positively Associated with Longer Leukocyte Telomere Length in the Nurses' Health Study by Liu JJ1, Crous-Bou M2, Giovannucci E3, De Vivo I4. (PubMed)
(2) Caffeine consumption and telomere length in men and women of the National Health and Nutrition Examination Survey (NHANES) by Tucker LA1.(PubMed)
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