Saturday 8 July 2023

#Chafuroside A (CFA) Isolated from #OlongTea Attenuates the #InflammatorySymptoms in Patients with #Asthma/#ChronicObstructivePulmonaryDisease (#COPD)

Kyle J. Norton

Green tea may be considered as a potential pharmacotherapy for asthma and chronic obstructive pulmonary disease (COPD), a renowned institute study suggested.

Green tea, a precious drink processes a number of health benefits known to almost everyone in Asia and the Western world. However, as yin in nature herbal medicine, or food, long-term injection of large amounts may obstruct the balance of yin-yang, inducing "excessive yin syndrome" or "yang vacuity syndrome" including weakened immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory. Adding a slice of ginger will resolved the problem.

Chronic obstructive pulmonary disease (COPD) is a condition of lung disease caused by obstruction of air flow in normal breathing.

In a total of 13,651 adults from three Dutch cities examined from 1994 to 1997. observation of dietary intake estimated using a food frequency questionnaire, and flavonoid intake calculated using specific food composition tables, showed a significant effect of flavonoid intake regularly in reduced risk COPD.

According to the returned questionnaire, total catechin, flavonol, and flavone intake was positively associated with FEV1 in air flow of a deep breath and inversely associated with chronic cough and breathlessness, common symptoms of chronic obstructive pulmonary disease (COPD).

More specifically, Dr. Tabak C, the lead author said, "Flavonol and flavone intake was independently associated with chronic cough only"

Furthermore, Chafuroside A (CFA), a water-soluble flavone C-glycoside, isolated from oolong tea, in oral administration exhibited at 0.5mg/kg or higher exhibited a profound effect in attenuated inflammatory symptoms in a dose-dependent manner, in experimental asthma/chronic obstructive pulmonary disease (COPD)-like model.

In fact, Biomarker profiling revealed that the CFA/SAM at 0.1mg CFA/kg equipotent to CFA at 1.0mg/kg testing result also expressed protective activity against antigen-induced airway inflammation.

Taking together, there is no doubt that green tea may be used as a therapeutic and functional food for reduced risk and treatment of chronic obstructive pulmonary disease (COPD) through expression of plant phytochemicals, but large amount intake regularly should be taken with care in prevented toxicity.


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Author: Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Phytoceuticals: the new 'physic garden' for asthma and chronic obstructive pulmonary disease by Grandhi S1, Donnelly LE, Rogers DF. (PubMed)
(2) Chronic obstructive pulmonary disease and intake of catechins, flavonols, and flavones: the MORGEN Study by Tabak C1, Arts IC, Smit HA, Heederik D, Kromhout D.(PubMed)
(3) Self-assembled micellar formulation of chafuroside A with improved anti-inflammatory effects in experimental asthma/COPD-model rats by Onoue S1, Matsui T, Aoki Y, Ishida H, Nukaya H, Kou K, Yamada S.(PubMed)

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