Scientists who work for big pharmaceutical companies have tried to mimic and replace the effectiveness of herbal phytochemical single ingredients with their synthetic version, which can be patented for commercial profits.
Even they know exactly the discovery in the treatment of certain diseases may induce serious side effects.
Therefore, if you are taking any conventional medicine, please discuss the adverse effects with your doctor.
A recent study suggested that Cat's Claw may be effective to cure type 1 diabetes induced by Th1/Th2 (T cell) cytokine production.
Unlike type 2 diabetes which is caused by Insulin resistance due to an unhealthy diet, genetics,.... and lifestyle, type 1 diabetes is a chronic disease characterized by an inability of the pancreas in produced insulin. a hormone with function in normalized the level of glucose caused by the immune system mistakenly attacks and destroys the beta cells in the pancreas.
Researchers do not know why the immune system produces autoantibodies.to attack the pancreas beta cells?
Patients with type 1 diabetes are associated with classical symptoms of frequent urination, increased thirst, increased hunger,..... and weight loss.
Some scientists in the differentiation of the difference between type 1 and type 2 diabetes found that the symptoms of type 2 diabetes are developed over a long period of time compared to the short period of time in type 1 patients.
According to the statistic in 2015, over 30 million Americans, or 9.4% of the population, had diabetes, including 125 million children and adults who had developed type 1 diabetes.
Patients with type 1 diabetes must inject insulin for survival, however, a healthy diet and lifestyle are also a must to improve quality of life and reduce the risk of diabetic complications.
If Untreated or poor management, type 1 diabetes can cause long-term complications of heart disease, stroke, kidney failure, foot ulcers,...... and eyes damage
Cat's claw found in the tropical jungles of South and Central America, is a genus Uncaria, belonging to the family Rubiaceae, used in traditional medicine over two thousand years as a tonic, contraceptive, anti-inflammatory and infectious agent, and to treat diarrhea, rheumatic disorders, acne, diabetes, cancer and diseases of the urinary tract, etc.
In vivo, immunotoxicity testing, BALB/c male mice treated once a day with 125, 500, or 1250 mg/kg of U. tomentosa extract for 28 days, increased the number of T helper lymphocytes and B lymphocytes.
The whole herb medicine also significantly exerted a large stimulatory effect on lymphocyte(a form of small white blood cell) viability.
Another study involved C57BL/6 male mice injected with MLDS (40 mg/kg) orally treated with UT at 10-400mg/kg during 21 days, which showed to express significant protection against the loss of insulin-secreting presented β-cells, through modulated the production of two helper T cell classes, known as Th1 and Th2, with increased levels of type-2 T helper cells and mast cells, known as IL-5 and the protein regulated activities of white blood cells known as IL-2.
Further linking Interleukin-2 effected on type I diabetes, the study of Interleukin-2 and type 1 diabetes and several autoimmune diseases suggested that depended on interleukin-2 (IL-2) in proliferating and controlling the T effector cells (Teff) reaction, low dose IL-2 treatment at the initial time of diabetes can rescue insulin secretion by restoring proteins expression.
Dr. Rosenzwajg M, the lead author said, " Regulatory T cells (Tregs) play a major role in controlling effector T cells (Teffs) responding to self-antigens, which cause autoimmune diseases.,....and expanding/activating Tregs with low-dose interleukin-2 (IL-2) could provide immunoregulation without immunosuppression"
Cat's Claw may be effective in protein-regulated activities of white blood cells, known as IL-2 through improvement of immune function in induced immunosuppression cause of Type I diabetes, but the quantity intake should only be prescribed by professional herbalist to prevent toxicity.
However, further data collection on studies performed with human consumption during the course of the disease will be necessary to complete the picture of its anti type 1 diabetes possibilities.
And intake of Cat's Claw supplements and phytochemicals should be taken with care, as acute liver toxicity caused by overdoses had been reported in a number of cases.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Prevention of experimental diabetes by Uncaria tomentosa extract: Th2 polarization, regulatory T cell preservation, or both? by Domingues A1, Sartori A, Golim MA, Valente LM, da Rosa LC, Ishikawa LL, Siani AC, Viero RM.(PubMed)
(2) Uncaria tomentosa aqueous-ethanol extract triggers an immunomodulation toward a Th2 cytokine profile by Domingues A1, Sartori A, Valente LM, Golim MA, Siani AC, Viero RM. (PubMed)
(3) Interleukin-2 and type 1 diabetes: new therapeutic perspectives by Hartemann A1, Bourron O.(PubMed)
(4) Interleukin 2 in the pathogenesis and therapy of type 1 diabetes by Rosenzwajg M1, Churlaud G, Hartmann A, Klatzmann D.(PubMed)
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