Kyle J. Norton
Good news to people with hypertension, Aloe Vera may be a potential therapeutic agent for lowering high blood pressure a renowned University study suggested.
Hypertension is a condition of abnormally high blood pressure, leading to symptoms of headaches, shortness of breath or nosebleeds......
Hypertension is a measurement with home systolic/ diastolic BP > or = 135/85 mmHg.
According to statistics, the prevalence of hypertension affects over 39.4% of men and 29.3% of women in the Western World.
Prolong untreated hypertension is found to induce complications of strokes, heart attacks, heart failure, or kidney disease.
Some researchers suggested that patients who are actively in modulated daily high blood pressure may be benefits in reduced risk of stroke by 35%, heart attack by 20%, and heart failure by 50%.
According to the WHO-based Healthy Diet Indicator (HDI), the American Heart Association 2006 Diet and Lifestyle Recommendations(4),
* The prevalence of untreated hypertension and treated hypertension was 22.4% and 8.5%.
* Patients with untreated hypertension had significantly lower HDI and AI-84 scores compared with non-hypertension.
* After adjusting for age, energy intake, smoking habit, alcohol drinking, physical activity and salt intake, a low adherence to HDI and a lowest quartile of AI-84 score were associated with a significantly higher prevalence of untreated hypertension, with an OR of 3.33 (95% CI 1.39 to 7.94, p=0.007) and 2.23 (1.09 to 4.53, p=0.027), respectively.
These results are agreed to the general and popular belief that an unhealthy diet plays an important role in the induction of high blood pressure. Furthermore, lower dietary quality was associated with an increased prevalence of untreated hypertension.
People who eat more fruits and vegetables compared to their average daily intake are associated with a significantly lower risk of hypertension.
Dr. Utsugi MT in the comparison of fruit and vegetable intake daily said, "The highest-tertile consumptions of fruits, vegetables, potassium, and vitamin C were associated with a significantly lower risk of hypertension (45%, 38%, 46%, and 43% lower risk of home hypertension, respectively(5)".
Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan. It has become very popular for commercial cultivation due to enormous health benefits. Aloe vera has also been used in herbal medicine in treating many kinds of disease, including wounds, burn healing, minor skin infections, sebaceous cysts, diabetes, and elevated cholesterol,
According to the Hamdard University, aloe-emodin, aloin A, a chemical compound found in Aloe Vera showed to express hypotensive effects by lower mean arterial blood pressure by 26 %, 52 %, and 79 % in the corresponding doses of 0.5, 1, and 3 mg/kg in an animal study.
Dr. Saleem R, the lead author of the study suggested that Aloe-emodin has emerged as a potent hypotensive agent in the current pharmacological investigation.
In a total of In a double-blind, placebo-controlled, crossover study, healthy, Aloe-emodin, another major chemical compound\ inhibited vascular smooth muscle stiffness, a condition in the development of hypertension, involved cells in supporting structural and biochemical and the interior surface of blood vessels.
In hypertension, increased large-artery stiffness is partly due to the intrinsic mechanical properties of vascular smooth muscle cells.
More importantly, in smooth muscle cells derived from hypertensive and control rats study, treatment of Aloe-emodin also significantly reduced hypertension by improving the elastic value of vascular smooth muscle cells, through its effects on vascular smooth muscle cell cytoskeletal proteins in the regulated function of cell division.
Other researchers suggested that the antihypertensive properties of Aloe-emodin may be a result of inhibition of tonic tension and regulated apoptosis, pro- and anti-apoptotic activities on vascular smooth muscle cells.
With all the information collected, Aloe Vera may have an antihypertensive effect in regulated protein in cell production on vascular smooth muscle which is the main cause of high blood pressure, but more precisely understanding may be necessary to reassess this pharmaceutical value.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) Hypotensive effect of chemical constituents from Aloe barbadensis by Saleem R1, Faizi S, Siddiqui BS, Ahmed M, Hussain SA, Qazi A, Dar A, Ahmad SI, Qazi MH, Akhtar S, Hasnain SN. (PubMed)
(2) Increased vascular smooth muscle cell stiffness: a novel mechanism for aortic stiffness in hypertension by Sehgel NL1, Zhu Y, Sun Z, Trzeciakowski JP, Hong Z, Hunter WC, Vatner DE, Meininger GA, Vatner SF. (PubMed)
(3) Emodin inhibits tonic tension through suppressing PKCĪ“-mediated inhibition of myosin phosphatase in rat isolated thoracic aorta by Lim KM1, Kwon JH, Kim K, Noh JY, Kang S, Park JM, Lee MY, Bae ON, Chung JH.(PubMed)
(4) Diet quality and adherence to a healthy diet in Japanese male workers with untreated hypertension by Kanauchi M1, Kanauchi K(PubMed)
(5) Fruit and vegetable consumption and the risk of hypertension determined by self-measurement of blood pressure at home: the Ohasama study by Utsugi MT1, Ohkubo T, Kikuya M, Kurimoto A, Sato RI, Suzuki K, Metoki H, Hara A, Tsubono Y, Imai(PubMed)
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