Dandelion (Taraxacum officinale) Processes Diuretic Property

By Kyle J. Norton

The diuretic effect is the activity of substances that promote urinary secretion.

Diuretics medicines are used for the treatment of water retention or edema by removing fluids from the body.

Water retention or edema is a condition of excess fluids that build up inside your body, including the circulatory system or within tissues and cavities. 

Edema can cause swelling in the hands, feet, ankles, and legs.

Many diuretics medicine can interfere with the functioning kidney in the regulation of the levels of water in the body, leading to worsening kidney function and abnormal electrolyte levels.

Certain medications that treat conditions of high blood pressure, glaucoma, and edema can damage kidney function by overworking the kidney in water release.

Dr. Yusra Habib Khan, the lead author in the study "Chronic Kidney Disease, Fluid Overload and Diuretics: A Complicated Triangle" said, "The use of diuretics was associated with adverse renal outcomes indicated by a decline in eGFR (Glomerular filtration rate (GFR) is a measure of the function of the kidneys) and increased risk of (renal replacement therapy) RRT initiation in our cohort of NDD-CKD patients".

Therefore, the intake of medicine that has a negative effect on kidney function and diuretics medicine should be taken with extreme care.

Dandelion is a herbaceous perennial plant, genus Taraxacum, belongings to the family Asteraceae, native to temperate regions of the world. It has been used in traditional and herbal medicine to treat gout, eczema, acne, gall bladder, kidney, liver, and urinary disorders, hypoglycemia, dyspepsia with constipation, edema, blood pressure, and heart weakness, chronic joint, skin diseases, etc.

On finding a natural ingredient for the improvement of edema, scientists examined the dandelion diuretic effect in 17 individuals.

Participants who entered the study have a volume of urinary output and fluid intake recorded that were established 2 days prior to dandelion dosing (8 mL TID) and monitored throughout a 1-day dosing period and 24 hours postdosing.

According to the records returned by the participants, all populations showed a significant increase in the frequency of urination in the 5-hour period after the first dose.

Furthermore, a significant increase in the excretion ratio in the 5-hour period after the second dose of the extract was also reported by the participants.

However, there was no change in the measured parameters at the third dose.

Based on the evidence, researchers said, "T. Officinale ethanolic extract shows promise as a diuretic in humans. Further studies are needed to establish the value of this herb for the induction of diuresis in human subjects".

Taken altogether, dandelion may be considered a diuretic remedy, pending the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) The diuretic effect in human subjects of an extract of Taraxacum officinale folium over a single day by Clare BA1, Conroy RS, Spelman K. (PubMed)
(2) Chronic Kidney Disease, Fluid Overload, and Diuretics: A Complicated Triangle by Yusra Habib Khan,1,2,* Azmi Sarriff,1 Azreen Syazril Adnan,2,* Amer Hayat Khan,1 andTauqeer Hussain Mallhi. (PMC)

Healthyfood Cranberry Prevents and Reduces the Risk of Colitis, Scientists Say

By Kyle J. Norton


Colitis is a medical condition characterized by the inflammation of the large intestine, including the colon, caecum, and rectum.

Most cases of colitis are caused by infection, such as bacteria like C. difficile, viruses, and parasites, and inflammatory bowel diseases (IBD) such as Crohn's disease and ulcerative colitis (UC).

However, according to the study by the Catholic University of the Sacred Heart, depending on the causes, colitis can be classified into microscopic colitis, ischemic colitis, segmental colitis associated with diverticula, radiation colitis, diversion colitis, eosinophilic colitis, and Behcet's colitis.

The most common symptoms of colitis are abdominal pain and diarrhea, bleeding per rectum, distention with bloody diarrhea, abdominal bloating and flatulence, and changes in bowel habits.

In severe cases, patients may also experience symptoms of elevated liver enzymes, leukopenia, thrombocytopenia, severe peripheral arthralgias, and chronic watery diarrhea.

Believe it or not, 55 percent of patients stated that UC symptoms over the past year had affected their quality of life, while physicians and nurses estimated that 35% to 37% of patients would have a reduced quality of life.

Conventionally, treatments of colitis are total depending on the type and severity of the condition. For example, in patients with inflammatory bowel disease (IBD), Self-care at home through home Telemanagement, Web-guided therapy, and pain management are the most common approach accompanied by biological therapy, if necessary.

Some researchers suggested, the promotion of the Western diet over the past few decades may be the leading cause of colitis in patients with IBD.

Dr. Jimmy K. Limdi wrote, "The parallelism between “westernization” and particularly high dietary intakes of total fat (particularly animal fats, ω-6 polyunsaturated fatty acids (PUFA), milk fats), refined sugars, meat and lower intakes of fruit and vegetables, implicates diet in the great risk of developing IBD".

And, "Diet may influence intestinal inflammation through several biologically plausible mechanisms including dietary antigen presentation, alterations in the gut microbiome, the mucosal immune system and epithelial barrier function among others".

Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry is cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine for the treatment of wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.

On finding a potential compound for the treatment of IBD, researchers examined the effects of cranberry products on preventing dextran sulfate sodium-induced murine colitis.

According to the tested differentiation, both cranberry extract and dried cranberries-fed groups had significant activity against the disease index.

However, dried cranberries were more effective in preventing colitis compared to cranberry extract.

Moreover, both cranberry applications also showed a significant effect on preventing the shortening of colon length.

Biomarkers associated with inflammatory bowel diseases (IBD) such as colonic myeloperoxidase activity were attenuated in animals fed dried cranberries compared to the controls.

Additionally, dried cranberries also inhibited much better results against the production of pro-inflammatory cytokines caused by the injection of dextran sulfate sodium, compared to the controls.

Based on the findings, researchers wrote, "The current report suggests that cranberries can be applied to prevent and reduce the symptoms of IBD".

Taken altogether, cranberry may be considered a remedy for the prevention and treatment of colitis in IBD patients, pending the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

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Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Diets enriched with cranberry beans alter the microbiota and mitigate colitis severity and associated inflammation by Monk JM1, Lepp D2, Zhang CP1, Wu W2, Zarepoor L1, Lu JT1, Pauls KP3, Tsao R2, Wood GA4, Robinson LE5, Power KA. (PubMed)
(2) Preventive effects of cranberry products on experimental colitis induced by dextran sulfate sodium in mice by Xiao X1, Kim J1, Sun Q1, Kim D2, Park CS3, Lu TS4, Park Y. (PubMed)
(3) Colitides by Tortora A1, Purchiaroni F, Scarpellini E, Ojetti V, Gabrielli M, Vitale G, Giovanni G, Gasbarrini A. (PubMed)
(4) Dietary practices and inflammatory bowel disease by Jimmy K. Limdi. (PMC)

Healthyfood GreenBeans Maybe Potent Against Prostate Cancer, Researchers Say

By Kyle J. Norton

Cancer is a class of diseases associated with abnormal cell growth in a specific tissue of an organ, due to the alternation of DNA.

A primary tumor or original tumor is a tumor of the original site where it first arose and the tumor progression began and proceeded to yield a cancerous mass.

Cancer cells that grow to their tumor size, can invade and kill their neighbor cells by producing abnormal or excessive signaling chemicals (hormones or cytokines) which upset the normal chemical balance of the body and alter the metabolic pathways, leading to disordered and violent cellular behavior.


At the early stage, due to the small size of the tumor, most patients are asymptomatic.

Prostate cancer is a medical and chronic condition in which the cells of the prostate have become cancerous due to the alternation of the cell's DNA.

Most prostate cancers are slow-growing and enlarged prostate and prostate cancer may be detected during the Physical (rectum) exams.

Primary prostate cancer normally starts from the cell on the surface of the inner lining of the prostate tissue and gradually spreads to the deeper part of the prostate.

At the early stage, patients may not experience any symptoms, However, at the advanced stage, prostate cancer can induce symptoms of blood in the urine, frequent urination, and urinary difficulty.

The cancer cells at this stage can also travel a distance away from the prostate to invade other healthy tissue and organ, leading to secondary metastasis tumors.

According to the statistic, the 5-year survival rate for local and regional (stage 0 and 1) stages of prostate cancer is nearly 100%.

Therefore, men who are at higher risk of prostate cancer due to family history and increase in age and inherited gene changes should have their prostate gland checked annually.

Believe it or not, more than 80% of prostate cancers are diagnosed in men who are 65 or older.

Dr. Anton Stangelberger,, the lead scientist at the joint study led by the University of Vienna, wrote, "
Due to increasing life expectancy and the introduction of prostate-specific antigen (PSA) screening, a rising number of elderly men are diagnosed with prostate cancer. Besides PSA serum levels and Gleason score, age is considered to be a key prognostic factor in terms of treatment decisions".


And, " Not every man who is diagnosed with prostate cancer will develop the clinically significant disease. This has led to the concept of expectant management for screen-detected, small-volume, low-grade disease, with the intention of providing therapy for those men with disease progression.".

Green bean is a genus of Phaseolus Sensu Stricto, containing 55 different species, belongings to the family Fabaceae and native to the New World tropics and grown in Europe for its attractive flowers and fleshy immature pods. It can be classified into two major groups, bush beans, and pole beans.

On finding a potent compound that processes chemopreventive activity, researchers examined BN999, a fermentation product of soybean, black bean, and green bean mixture in the inhibition of the growth of human prostate cancer.

The application of the mixed product showed a significant effect on inhibiting the growth of prostate adenocarcinoma PC-3 cells without causing obvious side effects.

Furthermore, BN999 induced apoptosis in colon cancer cells without affecting the healthy cells.

Based on the findings, researchers after taking into account co and confounder wrote, "these data suggest that BN999 has the potential to be used as cancer chemoprevention or therapeutic agent".
Taken altogether, green beans used combined with fermentation products of soybean, the black bean may be used as an adjunct therapy for the prevention of prostate cancer, pending the confirmation of a larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Fermentation product of soybean, black bean, and green bean mixture induces apoptosis in a wide variety of cancer cells by Chia JS1, Du JL, Wu MS, Hsu WB, Chiang CP, Sun A, Lu JJ, Wang WB. (PubMed)
(2) Prostate Cancer in Elderly Men by Anton Stangelberger, MD,* Matthias Waldert, MD,* and Bob Djavan, MD, Ph.D. (PMC)

Lycopene Inhibits Metabolic Diseases in Obese

By Kyle J. Norton

A metabolic profile is a tool to diagnose metabolic disease.

A metabolic disease is a group of medical conditions that disrupt normal cell metabolism in converting food to energy.

The most common causes of metabolic disease are genetic prepositions. However, people with the mutated gene may remain healthy for years.

Interestingly, cellular stress and family history have been found to be major causes of the initiation of the symptoms of metabolic disease, epidemiologically.

According to statistics, metabolic disease is uncommon in the US. Metabolic disorders affect approximately 1 in 1,000 individuals.

As of today, there is no effective treatment of metabolic disease. Some children with metabolic disease diagnosed at an early age may respond very well to therapy. However, many do not respond well to therapy and cause severe problems, despite the early diagnosis.

Obesity is a medical and chronic condition caused by long-term excessive body fat accumulated. Overweight is a condition of excess body weight relative to height.

According to the Body Mass Index(BMI), people who have a BMI between 25 to 29.9 are considered overweight and a BMI of over 30 is an indication of obesity.

The formula of the BMI indexBMI= weight (kg)/ height (m2)

According to the statistic, 68% of the American population is either overweight or obese. However,
in 2016, more than 1.9 billion adults, 18 years and older, were overweight, including over 650 million were obese worldwide.

Lycopene is a phytochemical found in tomatoes in the class of carotenoid, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,

Tomatoes provide about 80% of the lycopene in the world diet. In plants, lycopene protects the host against excessive photodamage and performs various functions in photosynthesis.

On finding a potential compound for the treatment of metabolic disease, researchers compared the effect of lycopene and tomato powder on obesity-associated disorders in an animal model.

Male C57BL/J6 mice selected to the study were assigned into four groups to receive: control diet (CD), high-fat diet (HFD), a high-fat diet supplemented with lycopene or with tomato powder (TP) for 12 weeks.

In HFD experimental mice, lycopene and TP supplementation significantly reduced adiposity index, organ, and relative organ weights, serum triglycerides, free fatty acids, 8-iso-prostaglandin GF2α, and improved glucose homeostasis, without affecting the total body weight. 

Furthermore, lycopene and TP supplementation protected the liver cell against HFD-induced hepatosteatosis and hypertrophy of adipose tissues.

Moreover, levels of pro-inflammatory cytokines induced by HFD also were reduced observed by the decreased mRNA expression in the liver and in the epididymal adipose tissue.

Additionally, levels of phosphorylation of IκB, and p65 associated pro-inflammatory responses were also decreased through the applications' anti-inflammatory activity.

Collectively, researchers said, "These results suggest that lycopene or TP supplementation display similar beneficial health effects that could be particularly relevant in the context of nutritional approaches to fight obesity-associated pathologies".

Taken altogether, lycopene and tomato may be considered remedies for the prevention and treatment of metabolic diseases, pending the confirmation of the larger sample size and multicenter human study.

Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You.  How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Lycopene and tomato powder supplementation similarly inhibit high-fat diet induced obesity, inflammatory response, and associated metabolic disorders by Fenni S1,2, Hammou H2, Astier J1, Bonnet L1, Karkeni E1, Couturier C1, Tourniaire F1, Landrier JF. (PubMed)

Omega-3 Fatty Acids May Be Potent Against Mild to Moderate Depression

By Kyle J. Norton

Depression is a normal response as part of our daily lives such as the loss of s job, the death of a loved one, and illness.

Over 30 million Americans suffer from depression and the amount is increasing at an alarming rate. 

Depression is a mental health disorder that can affect the way you eat, sleep, and the way you feel about yourself. 

The mild case of depression can be treated successfully by a variety of self-care techniques. Others require the treatment of medication, such as antidepressant medications and psychotherapy that help to reduce and sometimes eliminate the symptoms of depression.

Depression can be classified into 3 types, including

*Reactive depression
Reactive depression is the reaction caused by emotional swings affecting anyone at one time in his and her life, such as the death of a loved one, loss of financial stability, or chronic diseases. 

People suffering from reactive depression may lose interest in doing things that provide pleasure. These people generally still function in daily activity normally. Most people suffering from reactive depression may see the symptoms disappear gradually over time, some may require support from others or take antidepressant medications.

* Physical depression
This type of depression is caused by chemicals imbalance in the brain as resulting from chronic illness such as hormone imbalance, immune disorder or nutritional deficiency. 

People suffering from physical depression may lose interest or pleasure in almost everything and generally have a negative impact on every function in daily life.

* Manic depression
This is a severe type of physical depression. In medical terms, manic depression is characterized by wide mood swings with periods of both depressions, mania, and a variety of other significant symptoms not present in other types of depression such as the fluctuation between periods of extreme energy and vivacity with those of complete hopelessness.

Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.

The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

On finding a potential phytochemical for the treatment of depression, researchers examined the effects of a combined intervention of omega-3 polyunsaturated fatty acids (PUFAs) and psychoeducation on mild to moderate depression in workers compared to psychoeducation alone.

The double-blinded, parallel-group, randomized controlled trial that compared the intervention group, receiving omega-3 fatty acids 15 × 300 mg capsules containing 500 mg docosahexaenoic acid and 1000 mg eicosapentaenoic acid (EPA) per day, with a control group, receiving a placebo supplement for 12 weeks.

According to the results after 12 weeks, the Beck Depression Inventory®-II (BDI-II) scores were significantly lower in the placebo and omega-3 groups, compared to their respective baseline scores.

However, after 12 weeks of treatment, there is no significant difference between both groups with respect to changes in the BDI-II scores.

In other words, a combination of omega-3 fatty acids and psychoeducation and psychoeducation alone can contribute to the improvement of symptoms in people with mild to moderate depression.

Taken altogether, Omega-3 fatty acids used a combination with psychoeducation may be considered therapy for the treatment of depression, pending the confirmation of the larger sample size and multicenter human study.

Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Omega-3 polyunsaturated fatty acids and psychological intervention for workers with mild to moderate depression: A double-blind randomized controlled trial by Tayama J1, Ogawa S2, Nakaya N3, Sone T4, Hamaguchi T5, Takeoka A2, Hamazaki K6, Okamura H7, Yajima J8, Kobayashi M2, Hayashida M2, Shirabe S. (PubMed)

Dandelion (Taraxacum officinale) Processes Anti-Inflammatory Activity

By Kyle J. Norton

Inflammation is a natural response of the immune system in which the white blood cells of the first line of defense try to protect the body by destroying the foreign pathogens which try to enter the body through wound or tissue damage.

Inflammatory cytokines induce the Inflammatory processes in the body, triggered by the body's own immune system.

During the acute phase of infection, overproduction of proinflammatory cytokines may cause damage to nearby healthy cells, leading to the formation of scars.

Most cases of infection are stopped at the acute phase of infection as the immune system successfully kills off all invaders in a brief battle.

Some researchers suggested the immune system has evolved to protect our body over thousands of years with an aim to kill off all pathogens within a period in the range of 3 to 8 weeks. Otherwise, it will adapt to the new change, leading to chronic inflammation.

In other words, chronic inflammation happens when the immune response lingers, causing low-grade inflammation. Chronic inflammation over time may damage the body tissues and organs.

In some cases, the infection may be latent in which the pathogen remains within the body for a long time without producing any symptoms, such as the hepatitis virus.

Diseases associated with chronic inflammation include cancer, heart disease, rheumatoid arthritis, type 2 diabetes, and obesity.

Anti-inflammatory activity is the use of a substance or treatment for the treatment of od inflammation or swelling.

Anti-inflammatory protein in the body displays anti-inflammatory properties against the risk of autoimmune diseases and immune pathologies such as rheumatoid arthritis, psoriasis, or organ rejection.

Dandelion is a herbaceous perennial plant, genus Taraxacum, belongings to the family Asteraceae, native to temperate regions of the world. It has been used in traditional and herbal medicine to treat gout, eczema, acne, gall bladder, kidney, liver, and urinary disorders, hypoglycemia, dyspepsia with constipation, edema, blood pressure, and heart weakness, chronic joint, skin diseases, etc.

On finding a natural ingredient for the treatment of chronic inflammatory diseases, scientists examined the anti-inflammatory activity of taraxacum officinale (TO) filtered methanol extracts in LPS-stimulated human umbilical vein endothelial cells (HUVECs).

According to the results from the assays on HUVECs pretreated with 100 μg/ml TO for 1 h and then incubated with 1 μg/ml LPS for 24 h, TO filtered methanol extracts dramatically inhibited LPS-induced endothelial cell-monocyte interactions by reducing vascular cell adhesion molecule-1 and monocyte chemoattractant protein-1 associated with cellular inflammation found in various immunological disorders, including rheumatoid arthritis, asthma, transplant rejection.

Furthermore, TO filtered methanol extracts also inhibited the production of pro-inflammatory proteins found in inflammatory subjects.

In other words, TO suppressed the LPS-induced nuclear translocation of NF-κB, without affecting the pro-inflammatory cytokine MAPK activation.

Based on the results, researchers said, "Our findings demonstrated that methanol extracts of TO could attenuate LPS-induced endothelial cell activation by inhibiting the NF-κB pathway. These results indicate the potential clinical benefits and applications of TO for the prevention of vascular inflammation and atherosclerosis".

Taken altogether, dandelion may be considered a remedy for the treatment of diseases associated with chronic inflammatory diseases, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Effects of Dandelion Extract on the Proliferation of Rat Skeletal Muscle Cells and the Inhibition of a Lipopolysaccharide-Induced Inflammatory Reaction by Liu Q1, Zhao H2, Gao Y1, Meng Y1, Zhao XX1, Pan SN. (PubMed)
(2) Anti-inflammatory evaluation of the methanolic extract of Taraxacum officinale in LPS-stimulated human umbilical vein endothelial cells by Jeon D1,2, Kim SJ3, Kim HS. (PubMed)

Lycopene Isolated From Tomatoes Lowers the Levels of Hypercholesterolemia in Vivo

By Kyle J. Norton

The liver is the largest internal organ located in the upper right portion of the abdomen, beneath your diaphragm and above your stomach.

The liver produces bile that not only aids the digestive function in food absorption but also builds strong cell membranes, produces vitamin D and steroid hormone.

Hypercholesterolemia is a condition characterized by abnormally high levels of cholesterol in the bloodstream.

In other words, the condition is caused by either overexpression of low-density lipoprotein (LDL) or low levels of high-density lipoprotein (HDL).

Cholesterol, a waxy substance produced by the liver or the dietary in moderate amount source plays a critical to aid digestive function in absorbing nutrients, build strong cell membranes, produce steroid hormones and vitamin D. However, excessive amounts in the blood have been found to induce plaque built-up on the arterial wall, leading to heart disease and stroke.

According to the statistics provided by the CDC, hypercholesterolemia is a major risk factor of heart disease, a leading cause of death in the US. In the US, approximately, 71 million American adults (33.5%) have high low-density lipoprotein (LDL), or “bad,” cholesterol, and only 1 out of every 3 adults with high LDL cholesterol has the condition under control.

Similar to high blood pressure, people with hypercholesterolemia are asymptomatic. Patients with familial hyper cholesterol may experience symptoms of chest pain with activity. xanthomas, and cholesterol deposits around the eyelids.

Lycopene is a phytochemical found in tomato in the class of carotenoid, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,

Tomatoes provide about 80% of the lycopene in the world diet. In plants, lycopene protects the host against excessive photodamage and performs various functions in photosynthesis.

On finding a potential compound for the treatment of high blood cholesterol, researchers examined the role of lycopene (L) on proprotein convertase subtilisin/kexin type-9 against hypercholesterolemia.

Where Proprotein convertase subtilisin/kexin type 9 (PCSK-9) is a serine protease of the proprotein convertase (PC) family that has been found to affect the levels of low-density lipoprotein cholesterol (LDL-C).

In HFD rats, lycopene treatment significantly inhibited the levels of low-density lipoprotein by lowering the expression of hepatic PCSK-9 and HMG-CoA Reductase (or 3-hydroxy-3-methyl-glutaryl-CoA reductase or HMGR and increasing the expression of hepatic LDL-R with function to remove LDL.

Furthermore, lycopene treatment also ameliorated inflammation induced by the expression PCSK-9 by suppressing the inflammatory markers.

Based on the findings, researchers said, "Based on the above results, it can be concluded that lycopene exhibits potent hypolipidemic activities via molecular mechanisms that are either identical (HMGR inhibition) or distinct from that of statins".

Taken altogether, lycopene found in tomato may be considered supplements for the prevention and treatment of hypercholesterolemia, pending on the confirmation of the larger sample size and multicenter human study.

Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You.  How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Potential role of lycopene in targeting proprotein convertase subtilisin/kexin type-9 to combat hypercholesterolemia by Sultan Alvi S1, Ansari IA1, Khan I1, Iqbal J2, Khan MS. (PubMed)