Thursday 23 September 2021

Omega-3 Fatty Acids May Be Potent Against Mild to Moderate Depression

By Kyle J. Norton

Depression is a normal response as part of our daily lives such as the loss of s job, the death of a loved one, and illness.

Over 30 million Americans suffer from depression and the amount is increasing at an alarming rate. 

Depression is a mental health disorder that can affect the way you eat, sleep, and the way you feel about yourself. 

The mild case of depression can be treated successfully by a variety of self-care techniques. Others require the treatment of medication, such as antidepressant medications and psychotherapy that help to reduce and sometimes eliminate the symptoms of depression.

Depression can be classified into 3 types, including
*Reactive depression
Reactive depression is the reaction caused by emotional swings affecting anyone at one time in his and her life, such as the death of a loved one, loss of financial stability, or chronic diseases. 

People suffering from reactive depression may lose interest in doing things that provide pleasure. These people generally still function in daily activity normally. Most people suffering from reactive depression may see the symptoms disappear gradually over time, some may require support from others or take antidepressant medications.

* Physical depression
This type of depression is caused by chemicals imbalance in the brain as resulting from chronic illness such as hormone imbalance, immune disorder or nutritional deficiency. 

People suffering from physical depression may lose interest or pleasure in almost everything and generally have a negative impact on every function in daily life.

* Manic depression
This is a severe type of physical depression. In medical terms, manic depression is characterized by wide mood swings with periods of both depressions, mania, and a variety of other significant symptoms not present in other types of depression such as the fluctuation between periods of extreme energy and vivacity with those of complete hopelessness.

Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.

The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

On finding a potential phytochemical for the treatment of depression, researchers examined the effects of a combined intervention of omega-3 polyunsaturated fatty acids (PUFAs) and psychoeducation on mild to moderate depression in workers compared to psychoeducation alone.

The double-blinded, parallel-group, randomized controlled trial that compared the intervention group, receiving omega-3 fatty acids 15 × 300 mg capsules containing 500 mg docosahexaenoic acid and 1000 mg eicosapentaenoic acid (EPA) per day, with a control group, receiving a placebo supplement for 12 weeks.

According to the results after 12 weeks, the Beck Depression Inventory®-II (BDI-II) scores were significantly lower in the placebo and omega-3 groups, compared to their respective baseline scores.

However, after 12 weeks of treatment, there is no significant difference between both groups with respect to changes in the BDI-II scores.

In other words, a combination of omega-3 fatty acids and psychoeducation and psychoeducation alone can contribute to the improvement of symptoms in people with mild to moderate depression.

Taken altogether, Omega-3 fatty acids used a combination with psychoeducation may be considered therapy for the treatment of depression, pending the confirmation of the larger sample size and multicenter human study.

Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Omega-3 polyunsaturated fatty acids and psychological intervention for workers with mild to moderate depression: A double-blind randomized controlled trial by Tayama J1, Ogawa S2, Nakaya N3, Sone T4, Hamaguchi T5, Takeoka A2, Hamazaki K6, Okamura H7, Yajima J8, Kobayashi M2, Hayashida M2, Shirabe S. (PubMed)

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