The Adverse Effects of #Turmeric, According to Studies

Kyle J. Norton

Turmeric, the principal curcuminoid of the popular Indian spice, is a rhizomatous herbaceous perennial plant of the ginger family, Zingiberaceae, native to tropical South Asia. The herbs although have been found to process a number of medical health benefits advocated by medical literature, they also induced some adverse effects that users should be aware of.

Side effects of Turmeric
1. Overdose may cause gastrointestinal pain and discomfort
According to the joint study led by Mahidol University, Bangkok, a total of 367 primary knee osteoarthritis patients with a pain score of 5 or higher were randomized to receive ibuprofen 1,200 mg/day or C. domestica extracts 1,500 mg/day for 4 weeks.

Although the extract expressed a similar effect in reduced symptoms of pain in tested patients, it also was found to induce a number of events of abdominal pain/discomfort but was less intense in those treated with ibuprofen.

2. Allergic skin rashes, and Fever
The side effects were reported by the Bhavan's Swami Prakashananda Ayurveda Research Centre, in the study of 9 healthy volunteers between 20 and 33 years of age administered 0.6 ml of turmeric oil (TO) three times a day for 1 month and 1 ml in 3 divided doses for 2 months to test for hemoglobin, blood counts, liver and kidney functions, bleeding and clotting time and serum electrolytes initially and at 1 and 3 months of treatment.


3. Increased risk of bleeding
Intake of turmeric may increase the risk of bleeding due to anticoagulant activities exerted by its major bioactive compound curcumin and its derivatives, particularly, in people with bleeding disorders, according to Kyungpook National University.

4. People who plan to have surgery, should stop taking turmeric a few weeks in advance to reduce the risk of bleeding.

5. Induced gallbladder contraction
The dosage of curcumin capable of producing a 50% contraction of the bladder was 40 mg nonlinearly.


6. Low Blood pressure
Turmeric clinically expressed a significant effect in reduced blood pressure, therefor People with hypotension are advised not to take turmeric and its bioactive compound curcumin.


7. Kidney stone
Consumption of turmeric and its supplement can significantly increase the risk of kidney stones due to high levels of oxalate contents.


8. Increased risk of infertility in men
Intake of turmeric should be taken with care if you are planning of getting a conception as turmeric's curcumin was found to be an effective agent in inhibiting sperm forward motility by intracellular acidification and hyperpolarization of the sperm plasma membrane, the West Virginia University suggested.

9. Induced iron deficiency
Turmeric containing from 0.5 to 33 mg polyphenol per meal may be considered a potent inhibitor of iron availability (20-90%), reducing iron availability in a dose-dependent manner, the Dr, Tuntipopipat S, the lead author at Mahidol University.

10 and 11 Pregnancy and breastfeeding
Due to induced iron deficiency adverse effects, women are advised not to take turmeric during months of maternity and post-maternity to prevent reduced lactation to the mother and symptoms of
feeling weak and tired, feeling dizzy or cranky, headaches, shortness of breath, trouble concentrating, and a pale appearance to both.

Finally, Do not use the herb in newborns, children, or if you are pregnant and breastfeeding without approval from the related field specialist.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, healthblogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.

References
(1) Efficacy and safety of Curcuma domestica extracts compared with ibuprofen in patients with knee osteoarthritis: a multicenter study by Kuptniratsaikul V1, Dajpratham P1, Taechaarpornkul W2, Buntragulpoontawee M3, Lukkanapichonchut P4, Chootip C5, Saengsuwan J6, Tantayakom K7, Laongpech S8. (PubMed)(2) Anticoagulant activities of curcumin and its derivative by Kim DC1, Ku SK, Bae JS. (PubMed)
(3) Effect of different curcumin dosages on human gall bladder by Rasyid A1, Rahman AR, Jaalam K, Lelo A.(PubMed)
(4) Curcumin protects against cadmium-induced vascular dysfunction, hypertension, and tissue cadmium accumulation in mice byKukongviriyapan U1, Pannangpetch P2, Kukongviriyapan V3, Donpunha W4, Sompamit K5, Surawattanawan P(PubMed)
(5) Effect of cinnamon and turmeric on urinary oxalate excretion, plasma lipids, and plasma glucose in healthy subjects by Tang M1, Larson-Meyer DE, Liebman M.(PubMed)
(6) The Effect of Curcumin on Intracellular pH (pHi), Membrane Hyperpolarization and Sperm Motility by Naz RK(PubMed)
(7) Inhibitory effects of spices and herbs on iron availability by Tuntipopipat S1, Zeder C, Siriprapa P, Charoenkiatkul S.(PubMed)