Kyle J. Norton
Leukemia is a condition of abnormal increase of white blood cells produced by the bone marrow and/or the lymphatic system. Depending on the malignant granulocytes or lymphocytes, leukemia is classified into myelogenous or lymphoblastic leukemia.
Bone marrow is the soft tissue inside the hollow center of the major bone. including spine, pelvis, underarm, leg. etc.
According to the statistics provided by the leukemia research, leukemia is diagnosed 10 times more often in adults than children. Approximately, each year the disease causes the death of 68,000 Americans.
Acute leukemia is a condition caused by a rapid increase in the a number of extremely immature white blood cells which appear in the bloodstream into other parts of the body, including tissue and organs, including
*Acute lymphoblastic leukemia (ALL)
Acute lymphocytic leukemia (ALL) is a type of cancer of the abnormal growth of extremely immature lymphocytes overproduced by the bone marrow and/or lymphatic system.
All have a tendency to multiply quickly, which can lead to the death of other normal white blood cells in the bone marrow and/or lymphatic system. In ALL, lymphocytes appear immature in the bloodstream.
Acute lymphoblastic leukemia (ALL) is the most common children forms of leukemia with about 80% of all cases.
*Acute myelogenous leukemia (AML)
Acute myelogenous leukemia (AML) is a cancer of the myelogenous lining caused of the rapid growth of abnormal granulocytes accumulated in the bone marrow, interfering with the normal blood cells. In AML, granulocytes appear immature in the bloodstream.
In ALL, lymphocytes appear immature in the bloodstream. Acute lymphoblastic leukemia (ALL) is the most common children forms of leukemia with about 80% of all cases.
In finding a natural ingredient for the prevention and treatment of leukemia, scientists examined the antitumor effect of Alantolactone (ALT), an active component of the natural product Inula heleniumin on B cell acute lymphoblastic leukemia (B-ALL).
Elecampane, also known as Horse-heal (Inula helenium) is a perennial composite plant, genus nulla, belonging to Asteraceae, native to Southern Europe, and Asia.
The plant has been used in traditional and herbal medicine in treating bronchitis or emphysema, night sweats, pulmonary tuberculosis, irritating cough, catarrhal discharges, etc.
According to the tested analysis of B-ALL cells that were treated with various concentrations of ALT,
* ALT showed a good antitumor effect in B-ALL by inducing cytotoxicity.
* In vivo and in vitro, ALT induced the overexpression of ROS to cause cancer apoptosis by damaging the cancer cell DNA damage.
* In addition, the induction of over a load of ROS by ALT was attributed to the effects in the direct inhibition of reductase.
Based on the results, researchers suggest, "We found that ALT, a natural product, showing a promising tactic in the therapy of B-ALL by targeting ROS pathway".
Taken altogether, Dandelion may be considered a remedy for the treatment of acute lymphoblastic leukemia, pending the confirmation of the larger sample size and multicenter human study.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Targeting non-oncogene ROS pathway by alantolactone in B cell acute lymphoblastic leukemia cells by Xu X1, Huang L2, Zhang Z1, Tong J1, Mi J1, Wu Y3, Zhang C4, Yan H. (PubMed)
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