Monday, 10 July 2023

#Herbal Chaste Tree Berry Seeds Inhibits Cytokines and Enzymes Associated with Relieving #Symptoms of #Arthritis, Researchers Suggest

Kyle J. Norton

Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of years as an aphrodisiac herb and considered as Queen herb in treating menstrual problems and discomforts.

Arthritis, a common condition of pain and inflammation in the joints, the tissues, affects 54 million people in the US annually alone, according to the 2013-15 statistics.

In Freund's complete adjuvant (CFA) induced arthritis (AA) in a rat model. oral administration of treatment of Chaste Tree Berry seed expressed a strongly inhibited paw edema, reversed weight loss, and decreased arthritis score.

According to the Second Military Medical University, the efficacy of herbal medicine for the treatment of arthritis is the result in inhibition of pro-inflammatory cytokines and in the regulation of enzymes responsible for inflammation and pain. expression.

In support of the above, researchers in the examined histopathological studies found that Chaste Tree Berry showed a remarkable inhibition effect in decreased synovial inflammatory infiltration and synovial lining hyperplasia in the joints in animal models.

Some also researchers suggested that Chaste tree berry reduced symptoms of the pain of arthritis patients probably is associated with the blocking the stimulus by sensory neurons ability through mediating anti-inflammatory activity and interacted with the opioid system.

Taken together, Chaste Tree Berry (seed) processed analgesic properties may be used as therapeutic potential in ameliorated symptoms and treatment of inflammatory arthritis. A large amount of intake can only be prescribed by herbalists.


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Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Therapeutic effects of standardized Vitex negundo seeds extract on complete Freund's adjuvant-induced arthritis in rats by Zheng CJ1, Zhao XX1, Ai HW1, Lin B1, Han T1, Jiang YP1, Xing X2, Qin LP3. (PubMed)
(2) Antinociceptive activities of the liposoluble fraction from Vitex negundo seeds by Zheng CJ1, Huang BK, Han T, Zhang QY, Zhang H, Rahman K, Qin LP. (PubMed)

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