Tuesday, 4 July 2023

#Herbal #Anise Shows a Strong Laxative Activity on Constipation with no Adverse Effects, Researchers Suggest

Kyle J. Norton

Scientists may have found a natural health food for the treatment of constipation, some studies suggested.


Constipation is a condition of the digestive system characterized by infrequent bowel movements due to hard and dry stools.

Most people with long-term constipation experience symptoms of abdominal pain, bloating, and a feeling of not completely passing the bowel movement.

The untreated or prolonged period of constipation is associated with the complications of hemorrhoids, anal fissures, or fecal impaction.

Constipation is the most common gastro disorder in the US. According to Self-reported constipation, about 2% of the population describe constant or frequent intermittent episodes of constipation.


Women and adults ages 65 and older are at a higher risk of constipation.

A laxative is the primary treatment of patients with long-term constipation. However, long-term intake of the substances can adduct the function of bowel natural movement.

Some researchers cautioned that laxatives may cause side serious side effects, including bloody stools. severe cramps or pain, weakness or unusual tiredness, sometimes rectal bleeding, and imbalance of salts and minerals in the body.

If you are currently using laxatives please make sure you know all the side effects and how to deal with them, including the interreaction of laxatives with other medications.


Herbal Anise is a flowering plant of the species of Pimpinella anisum, genus Pimpinella, belonging to the family Apiaceae native to Egypt and the Mediterranean region.

The popular herb has been used in traditional herbal medicine as a fragrance in soaps, oils, and mouth fresheners and stomachic, antiseptic, anti-spasmodic, carminative, digestive, expectorant, stimulant, and tonic agent to treat head-lice and mites, increase blood pressure, prevent the formation of gas in the gastrointestinal tract and menstrual cramps, etc.

Ingredients
Besides the main ingredient Anethole, it also contains, D-pinene, I-phellandrene, Alpha-terpineol, Safrol, Methyl chavicol, Resin, Shikimic acid, etc.

Anise has been used as a laxative in assisting bowel movements in folk medicine worldwide, especially in Asia.

In the study to reaffirm the traditional use of herbal Anise for the treatment of constipation, researchers at the Universidade Federal do Rio Grande do Su, conducted an experiment to examine the effects of a phytotherapeutic formula in Brazil.

The formula contains Pimpinella anisum L.(Anise), Foeniculum vulgare Miller, Sambucus nigra L., and Cassia augustifolia.

The randomized, crossover, placebo-controlled, single-blinded trial included 20 patients with chronic constipation according to the criteria of the American Association of Gastroenterology.

Half of the subjects received the phytotherapic compound for a 5-day period, whereas the other half were received placebo for the same period.

Both treatment periods were separated by a 9-day washout period followed by the reverse treatment for another 5-day period.

After examining the two phases of the reported constipation questionnaire and assessing the intestinal transit, straining, stool consistency, and sensation of fecal obstruction or incomplete evacuation in the last 24 hours filled by patients on a daily basis, researchers found that patients received the formula show a statistically significant improvement of bowel function, but the quality of life did not show significant differences among the study periods, according to the WHOQOL-Bref.

The phytotherapeutic compound processed a laxative efficacy and is a safe alternative option for the treatment of constipation.

Further analysis also suggested that the phytotherapeutic compound is found to exert a small reduction in serum potassium levels during the active treatment.

Observation of clinical variables such as arterial blood pressure, heart frequency, and laboratory data did not show significant changes during the study, an indication of no adverse effects.

Dr. Picon PD, the lead author said, "The findings of this randomized controlled trial allow us to conclude that the phytotherapeutic compound assessed has laxative efficacy and is a safe alternative option for the treatment of constipation".

Taken together, herbal Anise used alone or combined with other herbal medicine may be considered an adjunct therapy for the treatment of constipation without inducing adverse effects


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Randomized clinical trial of a phytotherapic compound containing Pimpinella anisum, Foeniculum vulgare, Sambucus nigra, and Cassia augustifolia for chronic constipation by Picon PD, Picon RV, Costa AF, Sander GB, Amaral KM, Aboy AL, Henriques AT. (PubMed)

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